Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$110K - $130K *

Advance healthcare solutions by leading service delivery, optimizing operations, and enhancing customer engagement. Utilize your expertise to drive strategic initiatives, foster collaboration, and ens...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Champion comprehensive care by leading an interdisciplinary team, providing preventive and episodic health services, and managing chronic conditions for at-risk and elderly populations. Drive innovati...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$219K - $235K *

Champion strategic clinical program leadership, ensuring high-quality execution and collaboration across teams to advance R&D initiatives and lifecycle management in a flexible hybrid work environment...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a team that's dedicated to elevating patient care by leading clinical operations, driving excellence, and ensuring compliance in our Ambulatory Surgery Center. Your leadership will shape the futu...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Join a dynamic team to lead and scale clinical operations, overseeing performance and process optimization. Build accountable teams, manage metrics, and partner with stakeholders to enhance operationa...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$210K - $250K *

Empower communities by providing visionary clinical leadership in behavioral health. Collaborate with multidisciplinary teams to enhance patient care, drive quality improvement, and develop strategic...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $145K *

Lead transformative nursing services as a Chief Nursing Officer, driving clinical excellence, mentoring leaders, and enhancing patient-centered care in a dynamic behavioral health environment...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$125K - $150K *

Drive enterprise AI strategy and governance, enhancing employee capabilities and optimizing technology use. Collaborate across departments to ensure responsible AI adoption and maximize business outco...

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Lead transformative nursing practices and ensure high-quality patient care across the organization. Collaborate with senior leadership to drive strategic initiatives, enhance operational efficiency, a...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$136K - $204K *

Champion high-quality, patient-centered care by supporting executive management, overseeing operations, and driving strategic initiatives. Develop leadership skills and foster a culture of excellence...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Transform healthcare delivery by leading nursing and ancillary services, ensuring clinical excellence and operational efficiency in a dynamic rehabilitation environment. Collaborate with senior execut...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$107K - $199K *

Join a team that's driving strategic initiatives and operational excellence. This role collaborates with senior leadership to enhance growth plans, manage impactful projects, and ensure alignment acro...

Oregon, USRemote

1 month ago

  •   5 - 7 years exp.  •   Healthcare

$190K - $230K *

Unlock innovative approaches in Translational Medicine, leading biomarker strategies to bridge the gap between clinical research and development, and shaping impactful initiatives to advance drug effi...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Lead the charge in developing operational and financial strategies for laboratory services, ensuring compliance and quality standards while fostering interdisciplinary collaboration and driving growth...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Champion the future of health care operations by leading strategic initiatives, enhancing community partnerships, and ensuring quality patient care in a defined neighborhood. Drive growth and complian...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$67K - $101K *

Lead the charge in overseeing patient care operations, ensuring compliance with regulations, enhancing agency profitability, and motivating staff to deliver high-quality home health services while coo...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Champion operational excellence by overseeing facility management, regulatory compliance, and staff coordination in a dynamic healthcare environment. Drive strategic initiatives to enhance patient car...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$181K - $291K *

Unlock potential by leading quality improvement initiatives in healthcare. Collaborate with executives to enhance clinical quality management, drive operational efficiencies, and foster strong teams t...

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$181K - $291K *

Drive quality improvement initiatives by collaborating with leadership to enhance clinical outcomes and operational efficiency. Lead strategic planning and resource management to ensure effective impl...

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$181K - $291K *

Lead the charge in enhancing clinical quality management programs, collaborating with executives to drive operational improvements and efficiencies. Build strong teams and relationships to achieve opt...

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$111K - $178K *

Champion operational excellence by leading clinic practices, enhancing quality, and fostering collaboration among stakeholders to drive effective healthcare delivery across multiple regions...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$262K - $393K *

Champion the growth of clinical operations by leading strategic initiatives, managing performance-based medical management, and fostering strong provider relationships to enhance patient care and fina...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$83K - $137K *

Lead the charge in clinical research management, overseeing staff and operations while ensuring compliance with regulations. Collaborate with multidisciplinary teams to drive research initiatives and...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$130K - $195K *

Innovate member experience strategies by translating enterprise goals into actionable plans. Drive performance improvements in CAHPS and HOS programs through provider engagement and data analysis, ens...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $200K *

Drive strategic excellence in healthcare by leading business development, planning, and population health initiatives. Collaborate with teams to ensure that the mission and values guide MercyOne’s evo...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.