Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$80K - $95K *

Grow your career with a pivotal role in patient safety management, supporting event reporting and analysis across multiple sites. Collaborate with leaders and frontline staff to enhance safety practic...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Accelerate clinic operations by leading teams, managing budgets, and driving change. Foster an inclusive environment while ensuring high-quality service delivery and continuous improvement in a tertia...

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $190K *

Unlock potential by collaborating with care teams to manage and optimize medication therapies, ensuring patient safety and effectiveness in outpatient settings while guiding pharmacy trainees through...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $250K *

Engage as a strategic leader driving nursing excellence and patient care. Oversee facility-wide nursing practices, ensuring high-quality care and operational efficiency. Collaborate with executive tea...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Champion exceptional clinical operations by leading a dedicated team to enhance patient care, ensure compliance, and drive quality improvements in a dynamic environment focused on addiction services...

4 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$250K - $300K *

Join a dynamic ICU team as a Medical Director, leading critical care initiatives, managing a 20-bed unit, and fostering collaborative relationships with healthcare professionals to enhance patient out...

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Join a team that's dedicated to advancing radiopharmaceuticals! Lead CMC strategies and cross-functional collaboration to ensure successful readiness for commercial viability, market expansion, and co...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Drive clinical excellence by leading a team of healthcare professionals, ensuring quality patient care, safety, and productivity. Collaborate with advanced practice providers and manage clinical opera...

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $150K *

Drive full-cycle sales for global clinical operations, fostering client relationships and developing strategic plans for service growth in alignment with company objectives...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $105K *

Join a dynamic team to oversee clinical operations and ensure quality care delivery. Manage personnel and services while adhering to regulatory standards. Leverage your nursing expertise to enhance pa...

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$85K - $100K *

Lead the charge in overseeing clinical and non-clinical services, managing operations and personnel to ensure high-quality care delivery in a home health setting while adhering to regulatory guideline...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $120K *

Elevate your career by managing clinical operations and services, ensuring compliance with regulations, and leading a dedicated team to deliver exceptional home health care. Bring your nursing experti...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Manage clinical operations and services, ensuring quality care delivery. Supervise personnel and office functions while adhering to regulatory guidelines. Bring your expertise to enhance patient outco...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$163K - $221K *

Drive operational excellence in Central Sterile Processing by leading strategic initiatives, ensuring compliance, and fostering team development to enhance patient safety and service quality...

3 days ago

  •   11 - 15 years exp.  •   Healthcare

$110K - $130K *

Empower clinical research initiatives by managing a disease-focused portfolio, leading a dedicated team, and ensuring compliance and efficiency in trial operations while fostering collaboration and st...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Manage a clinical research portfolio, leading a dedicated team to drive innovative research. Oversee operations, ensure compliance, and collaborate with stakeholders to enhance program success and eff...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Manage clinical operations in a memory care and assisted living community, ensuring quality care and regulatory compliance while leading nursing staff and enhancing resident well-being through effecti...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$85K - $110K *

Champion client satisfaction by managing relationships and service delivery for healthcare clients. Oversee accounts, resolve issues, and collaborate with teams to enhance operational efficiency and c...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$284K - $385K *

Lead the charge in developing and implementing US medical strategies for a key asset, ensuring alignment across functions and fostering relationships with experts and stakeholders to advance clinical...

1 month ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$284K - $385K *

Advance your career by developing and overseeing medical strategies for a key asset, driving impactful collaborations, and fostering relationships within the healthcare landscape to address clinical n...

1 month ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Shape the future of healthcare as a VP Chief Medical Officer, leading clinical strategy and oversight. Collaborate with teams to ensure quality improvement, develop policies, and drive partnerships wh...

1 month ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$88K - $105K *

Drive clinical operations effectiveness through leadership and teamwork, enhancing patient care. Supervise nursing staff while overseeing recruitment, training, and strategic initiatives across multip...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$180K - $220K *

Shape the future of healthcare by overseeing clinical services, ensuring quality patient care, and collaborating with medical staff. This role requires strong leadership and decision-making skills to...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Elevate healthcare delivery by leading clinical services as a Site Medical Director, ensuring quality care and compliance while collaborating with providers and supervising staff to enhance patient ou...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Join a team that's driving HR excellence by aligning strategies with organizational goals. Lead talent acquisition, enhance employee engagement, and ensure compliance while fostering a positive workpl...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.