Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$160K - $200K *

Join a team that's building a new clinical research site from the ground up. As a Principal Investigator, you'll provide medical oversight, shape research initiatives, and engage with the community wh...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Drive the establishment of a new clinical research site, providing medical oversight and leadership for trials. Engage with the community, ensuring participant safety and data quality while contributi...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Build a new clinical research site by providing medical oversight and leadership. Partner with a dedicated team to ensure participant safety and data quality while advancing innovative therapies in a...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a team that's dedicated to enhancing health care quality through innovative program development, compliance monitoring, and leadership in stroke care coordination. Engage with healthcare professi...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$179K - $238K *

Empower clinical excellence by leading operations, education, and supply chain initiatives. Collaborate with executive leadership to standardize practices, enhance patient safety, and drive quality ou...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Lead the charge in advancing clinical excellence by overseeing nursing operations, fostering collaboration, and driving strategic initiatives to enhance patient care and outcomes across multiple units...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$117K - $161K *

Drive impactful clinical intelligence initiatives by analyzing AI opportunities, conducting feasibility studies, and collaborating with cross-functional teams to enhance patient care and operational e...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$300K - $350K *

Take ownership of trauma care as a Trauma Medical Director, leading a Level 1 ACS program, mentoring residents and collaborating within a stable, supportive team focused on surgical excellence and cri...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Healthcare

$200K - $250K *

Join us to lead clinical partnerships, influence medical practices, and shape innovative strategies. Use your medical expertise to enhance patient access and drive company growth while collaborating w...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$92K - $110K *

Champion the operational excellence of a Radiation Oncology department by managing clinical, administrative, and compliance functions. Lead a dedicated team to enhance patient safety, service quality...

4 days ago

  •   5 - 7 years exp.  •   Staffing

$85K - $100K *

Transform the quality of care in long-term facilities by leading dedicated teams, ensuring compliance, and fostering a nurturing environment that prioritizes resident well-being and satisfaction...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$250K - $300K *

Champion transformative transfusion medicine by leading clinical care, providing expert consultation, and fostering innovation in laboratory practices. Collaborate with hospitals on blood management a...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Transform patient care by leading interdisciplinary teams, ensuring quality and compliance in hospice services. Drive operational excellence while mentoring staff and enhancing patient-family experien...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$73K - $136K *

Help us enhance patient care by leading quality improvement initiatives through data analysis, collaboration, and implementation of best practices. Participate in committees to drive advancements in h...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $150K *

Shape the future of community mental health by leading operations and clinical programs. Collaborate with executive leadership to enhance service quality, drive strategic initiatives, and foster a cul...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$85K - $100K *

Lead the charge in enhancing rural health services by overseeing integrated care initiatives, fostering community partnerships, and guiding program development to improve access and sustainability acr...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $100K *

Champion clinic operational excellence by leading teams, overseeing daily functions, and driving patient experience in a fast-paced, patient-centric environment, while ensuring compliance and optimizi...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $100K *

Join a team that champions operational excellence and patient-centered care while leading a dedicated clinic team. Drive high engagement, optimize workflows, and ensure compliance, all while enhancing...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Shape the future of financial oversight by leading accounting, payroll, and budgeting functions to ensure financial accuracy and identify cost-saving opportunities while collaborating closely with upp...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$85K - $100K *

Transform operations at our community clinic by leading a dedicated team, ensuring efficient patient care, managing fiscal responsibilities, and fostering staff development while upholding high standa...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $105K *

Lead and empower a dedicated team of clinicians, ensuring exceptional patient care and compliance with hospice standards while fostering growth and collaboration within the interdisciplinary team...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$115K - $155K *

Contribute to enhancing patient experience by collaborating with clients and teams to develop scalable improvement resources, facilitating workshops, and amplifying thought leadership in healthcare...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Champion the delivery of exceptional cardiac care by overseeing multiple departments, ensuring quality standards, staff training, and operational efficiency while fostering a collaborative environment...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Empower your career by leading operations in a dynamic correctional healthcare environment. Collaborate with multidisciplinary teams to enhance service delivery and ensure compliance while fostering p...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$108K - $130K *

Drive excellence in clinical operations by overseeing inpatient nursing functions, optimizing throughput, and ensuring high-quality patient care. Collaborate with teams to enhance processes, complianc...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.