Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$120K - $145K *

Champion the development of clinical operations by managing a network of providers, establishing policies, and enhancing quality programs. Collaborate with leadership to ensure operational excellence...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$210K - $250K *

Join a dynamic mental health team as a Collaborating Psychiatrist, providing clinical oversight and direct patient care. Engage in meaningful collaboration with PMHNPs while ensuring compliance and de...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$270K - $280K *

Join a team that's driving clinical excellence by overseeing trial execution, managing timelines, budgets, and CROs. Collaborate with stakeholders to ensure compliance and quality while mentoring team...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Drive the integration of complex application solutions, collaborating with cross-functional teams to enhance efficiency and resolve issues, while providing expert guidance in a consultative role to en...

Chicago, ILRemote

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$125K - $150K *

Join a team that's dedicated to advancing radiopharmaceuticals! Lead CMC strategies and cross-functional collaboration to ensure successful readiness for commercial viability, market expansion, and co...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Drive full-cycle sales for global clinical operations, fostering client relationships and developing strategic plans for service growth in alignment with company objectives...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Champion clinical project success by leading operations, training teams, and ensuring compliance. Drive strategic planning and risk management while overseeing site performance and fostering collabora...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$144K - $245K *

Lead the design and execution of workforce development programs, ensuring compliance and timely deliverables. Collaborate across teams and stakeholders to create scalable systems that enhance healthca...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $190K *

Accelerate customer success by leading post-sales deployments of innovative AI solutions in healthcare. Shape operational strategies to ensure measurable outcomes, adoption, and expansion while drivin...

San Francisco, CARemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by driving technical integration and validation for Ambient AI Scribe initiatives. Collaborate with clinical teams to enhance workflows, troubleshoot issues, and ensure operational re...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$73K - $115K *

Unlock the potential of clinical documentation integrity by driving ICD-10-CM coding accuracy and enhancing provider education. Collaborate with cross-functional teams to support risk adjustment initi...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Champion client success by overseeing relationships, ensuring operational excellence, and mentoring teams to exceed expectations. Utilize analytics to drive performance and resolve issues, fostering c...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a team that's dedicated to enhancing client relationships and driving success. Oversee client performance, mentor staff, and ensure compliance while collaborating with various departments to deli...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Empower your career by providing analytic support for performance improvement and labor productivity initiatives. Collaborate with leaders to develop standards, enhance data integrity, and optimize be...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$160K - $220K *

Engage with healthcare professionals to enhance scientific dialogue and education in mental health. Build relationships, identify knowledge gaps, and support evidence-based treatment initiatives acros...

Ohio, USRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Transform healthcare delivery by leading a team of Medical Directors and Clinical Directors, driving clinical strategy and performance excellence across portfolios while fostering relationships and in...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Grow your career by optimizing clinical applications, enhancing radiology workflows, and collaborating with healthcare teams nationwide to ensure seamless operations and technical support across syste...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$235K - $265K *

Champion product innovation by leading a dynamic team to define strategy, drive decisions, and ensure successful launches that align with company growth and customer needs in the health technology sec...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$120K - $150K *

Empower change by leading strategic fundraising efforts! As a vital team architect, you'll cultivate relationships, drive grant strategies, and shape a culture of philanthropy that fuels innovative jo...

Washington, DCRemote

3 weeks ago

  •   8 - 10 years exp.  •   Media

$150K - $160K *

Join a team that's dedicated to transforming behavioral health operations by implementing strategic initiatives, ensuring quality standards, and enhancing support for clinic leaders. Collaborate acros...

Boulder, CORemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$223K - $313K *

Shape the future of healthcare by leveraging your clinical expertise to review Medicare drug appeals, ensuring compliance and optimal value-based care through collaboration and analysis of complex cas...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$135K - $237K *

Lead the charge in optimizing Utilization Management operations, driving project success, enhancing clinical collaboration, and ensuring compliance with regulatory standards to improve member outcomes...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$190K - $260K *

Transform client delivery in biotech by leading a high-performing team, driving operational excellence, and fostering innovation. Champion technology adoption and continuous improvement to enhance cli...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$93K - $120K *

Join a dynamic team as you manage clinical data throughout study lifecycles, ensuring compliance and quality. Collaborate with cross-functional teams to drive data strategy and support innovative solu...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$122K - $184K *

Drive operational excellence by leading physician practices in Ohio. Collaborate with clinical and regional teams to enhance performance, accountability, and patient experience while translating data...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.