Explore $100K+ Jobs in Oklahoma

Find professional opportunities across Oklahoma with salaries of $100,000 or more. Ladders features vetted jobs for experienced candidates seeking leadership, specialized, and other high-paying roles. Explore openings in Oklahoma City, Tulsa, and communities throughout the state, and discover opportunities that match your skills and career goals.

High-Paying Careers Across Oklahoma

Oklahoma’s economy includes established industries such as energy, aerospace, healthcare, manufacturing, finance, and technology. Employers may seek experienced professionals for roles in operations, engineering, corporate leadership, sales, information technology, and clinical or administrative management. Available positions and compensation vary by employer, location, experience, and specialization.

Find the Right Role for Your Experience

Use Ladders to explore vetted professional job listings and focus your search on roles with compensation of $100,000 or more. Review each posting for its responsibilities, qualifications, location, and compensation details. Set up a strong profile and tailor your resume to highlight measurable results, relevant expertise, and leadership experience.

Search Oklahoma Jobs on Ladders

Whether you’re considering a move to Oklahoma or looking to advance your career close to home, browse current high-paying opportunities and apply to positions that fit your background. New listings may appear as employers’ needs change, so check back regularly for the latest Oklahoma jobs.

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$100K - $120K *

Shape the future of executive recruitment by leading strategic sourcing, engaging high-level candidates, and collaborating with a dedicated team to uncover top talent. This role offers growth opportun...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Inspire patient recruitment strategies by leading a dynamic team, collaborating with senior management, and leveraging innovative tools to enhance enrollment across clinical trials while ensuring dive...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $250K *

Unlock potential by leading innovative clinical documentation initiatives that enhance quality, compliance, and revenue cycle outcomes. Collaborate with cross-functional teams to redefine workflows an...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$74K - $85K *

Lead the planning and execution of diverse research projects, ensuring alignment with organizational goals. Collaborate with stakeholders to manage timelines, deliverables, and budgets while fostering...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $160K *

Join a team that's transforming healthcare with AI solutions. As an AI Solutions Engineer, you'll develop integrations and tools that enhance customer workflows, bridging the gap between clients and o...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$274K - $371K *

Lead the early phase clinical development of innovative therapeutics, collaborating across teams to design and execute trials. Your expertise will directly influence strategy, protocol development, an...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Unlock potential by leading the full sales cycle in healthcare, engaging C-suite executives and driving strategic decisions. Leverage your experience to meet quotas, build account strategies, and enha...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$140K - $170K *

Elevate your career by managing a dynamic Palliative Care Program, providing clinical expertise, and leading a dedicated team. Drive process improvements and ensure high-quality patient care while fos...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$210K - $240K *

Lead strategic relationships with influential optometrists and ophthalmologists, shaping the Presbyopia ecosystem through education and engagement. Drive insights and collaboration across medical, mar...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $110K *

Transform financial operations by providing analytical support, enhancing reporting processes, and collaborating with cross-functional teams to drive profitability and efficiency in budgeting and fore...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$121K - $161K *

Transform your career by leading the design and implementation of Veeva Vault RIM, ensuring optimal performance and compliance while collaborating with cross-functional teams to enhance user experienc...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$140K - $150K *

Partner with us to deliver compassionate, whole-person care for patients with substance use disorders through our innovative telehealth platform, ensuring effective treatment and support in a fully re...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Pioneer customer success by nurturing strategic relationships, driving product adoption, and ensuring satisfaction. Leverage your expertise to mentor junior team members and shape customer success str...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Join us to lead payer contracting strategies, negotiate complex agreements, and enhance reimbursement performance across diverse healthcare models while managing a high-performing team in a dynamic, r...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$180K - $220K *

Empower innovation in clinical trials by developing strategies, overseeing operations, and cultivating partnerships. Drive excellence in research, enhance compliance, and manage a high-performing team...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$163K - $220K *

Transform vendor strategies and cost management across the organization. Drive financial performance with analytics, lead sourcing events, and collaborate with cross-functional teams to optimize value...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$150K - $206K *

Transform the accounting landscape by leading strategic initiatives that enhance operational efficiency, standardize processes, and drive technology integration, all while ensuring public company read...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$82K - $93K *

Lead the charge in ensuring medical transport flights are executed safely and efficiently. Your expertise in aviation will guide compliance with regulations while providing critical support to medical...

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$76K - $114K *

Grow your career with a dynamic role focused on driving sales and clinical engagement in Electrophysiology Ambulatory Surgery Centers. Leverage your clinical expertise to build relationships, enhance...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$274K - $371K *

Elevate patient care through innovative clinical strategies in obesity and cardiometabolic development. Collaborate across teams to design and implement late-phase studies, ensuring alignment with glo...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K *

Join a team that's dedicated to mentoring new graduates in dentistry. Enhance your skills as you provide comprehensive care, collaborate with a supportive team, and explore a promising career path in...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K *

Join a team that's dedicated to mentoring new graduates in dentistry. Enhance your skills as you provide comprehensive care, collaborate with a supportive team, and explore a promising career path in...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$190K - $225K *

Shape the future of healthcare by driving strategic KOL engagement and insight generation in rare neurology. Collaborate with thought leaders to influence brand strategy and enhance patient outcomes t...

RemoteRemote

1 month ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead complex compensation initiatives, ensuring equitable pay programs while managing projects. Serve as a subject matter expert in various compensation areas and collaborate with teams to enhance org...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Join our team to drive sales across a defined portfolio, engaging healthcare organizations with our innovative solutions. Own the sales cycle from prospecting to closing while collaborating with inter...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs can I find in Oklahoma?question toggle

    Listings may include professional and leadership roles in areas such as energy, aerospace, healthcare, technology, manufacturing, finance, engineering, operations, and sales. Job availability and compensation vary.

  • Which Oklahoma cities have high-paying job opportunities?question toggle

    Opportunities may be available in Oklahoma City, Tulsa, and other communities across the state. Check each listing for its location and whether remote or hybrid work is offered.

  • Does Ladders list jobs that pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with compensation of $100,000 or more. Review individual postings for specific salary information and qualifications.

  • How can I find Oklahoma jobs that fit my experience?question toggle

    Search current listings and compare each role’s requirements, responsibilities, location, and compensation. Tailor your resume to emphasize relevant skills, accomplishments, and experience.