Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$98K - $125K *

Lead the charge in sourcing and procurement for New Product Introductions, ensuring supplier readiness and cost efficiency. Collaborate with cross-functional teams to drive strategic sourcing initiati...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $231K *

Transform healthcare outcomes by leading a team of Clinical Program Consultants to analyze data, optimize clinical programs, and drive strategic initiatives that enhance customer health and reduce cos...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive client success by managing relationships, enhancing satisfaction, and identifying growth opportunities. Collaborate with internal teams to deliver exceptional service and exceed client expectati...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$111K - $150K *

Transform product strategy and execution by leveraging data insights, leading cross-functional teams, and prioritizing customer needs to drive product success and business growth in a dynamic environm...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$263K - $325K *

Advance your career by building and leading the pharmacovigilance function from the ground up. In this pivotal role, you'll oversee drug safety operations, collaborate with cross-functional teams, and...

United StatesRemote

Reposted today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$95K - $100K *

Join our dynamic team as a Technical Delivery Manager, overseeing AI-driven project delivery across diverse digital platforms. Ensure timely, high-quality outputs while leveraging innovative technolog...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$216K - $228K *

Transform the research landscape by defining and leading user research practices that connect customer insights to product design across multiple foundational areas, driving high-quality deliverables...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $115K *

Transform your career by leading financial strategy and operations for innovative service lines. Collaborate with senior leaders to enhance profitability, oversee budgeting, and drive growth initiativ...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Join a dynamic team as you drive continuous improvement initiatives, enhancing operational efficiency and fostering a culture of excellence across the organization. Collaborate with cross-functional t...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Accelerate sales growth by leading strategies and initiatives across the ANZ market. Collaborate with a multidisciplinary team to drive customer engagement, develop market strategies, and achieve reve...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$75K - $115K *

Unlock potential by sourcing top talent through innovative recruiting strategies. Engage with candidates, manage referrals, and support proposal efforts to build a robust talent pipeline for future op...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$130K - $160K *

Lead the technical direction for inhaled dry powder products, ensuring product performance and manufacturability while collaborating with cross-functional teams to navigate development and regulatory...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$64K - $162K *

Transform creative visions into reality by leading a talented design team, driving innovative strategies, and ensuring high-quality project execution across various media platforms while collaborating...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Join us to lead a dynamic team in optimizing revenue cycle operations for multiple clients. Drive continuous improvement and ensure client satisfaction while managing performance metrics and fostering...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$175K - $210K *

Champion the development and strategy of cutting-edge AI services, overseeing a dynamic team of ML engineers and scientists to deliver impactful, reliable, and clinically sound solutions that enhance...

United StatesRemote

1 month ago

  •   11 - 15 years exp.  •   Healthcare

$200K - $230K *

Champion a transformative member software experience, guiding strategy and design across the care journey. Leverage data and user insights to drive impactful solutions in a complex healthcare landscap...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$110K - $130K *

Tackle data-driven decisions as a senior product analyst, owning A/B testing design and analysis while collaborating across teams to enhance user experience and drive growth through insightful experim...

RemoteRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $110K *

Empower patient care by functioning as an Advanced Practice Nurse, collaborating with interdisciplinary teams to deliver quality health services, educate staff, and drive research initiatives for impr...

4 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $100K *

Advance impactful medical communications by crafting precise, engaging content. Collaborate with cross-functional teams to ensure accuracy and alignment with client objectives while mentoring junior s...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $210K *

Lead the charge in transforming people analytics by applying causal inference and advanced statistical methods to drive strategic decisions on recruitment, retention, and compensation across the organ...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$125K - $150K *

Champion growth by building strategic relationships and driving sales in the Healthcare sector. Leverage AI solutions to enhance customer engagement and achieve revenue targets while collaborating wit...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $120K *

Empower your veterinary career by providing urgent care for pets in a supportive, modern environment. Collaborate with a dedicated team to manage diverse cases while enjoying a flexible schedule and o...

4 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$165K - $215K *

Empower innovation in ophthalmic device development by leading global clinical strategies for surgical programs, from feasibility to regulatory submissions. Collaborate cross-functionally to drive pro...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$157K - $242K *

Join a team that's shaping groundbreaking hardware solutions by defining system architecture, integrating cross-functional requirements, and leading technical direction for complex, production-ready d...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $120K *

Transform healthcare delivery by providing emergency and primary care at remote worksites. Collaborate with clinical teams to ensure quality assurance and support field staff while maintaining essenti...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.