Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$150K - $230K *

Transform the oncology landscape by driving product success and building strong relationships with key stakeholders. Leverage your expertise to enhance patient access and deliver innovative solutions...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$135K - $155K *

Join a team that's dedicated to enhancing clinical workflows in Radiation Oncology. As a Clinical Success Manager, you'll train clinics, solve problems, and foster relationships to ensure customer sat...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$159K - $218K *

Advance your career by leading a dynamic sales team to drive growth in cardiovascular imaging. Shape strategies, enhance customer satisfaction, and achieve financial goals while making a significant i...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $145K *

Lead cross-functional teams to develop and execute a strategic product roadmap, integrating market insights and performance metrics to drive customer-centric solutions in the diagnostics and genomics...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$135K - $160K *

Lead the charge in transforming legal operations by advising corporate legal departments on strategy, technology, and process improvements. Drive complex engagements, build trusted relationships, and...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$110K - $130K *

Shape the future of healthcare by leading complex architectural and facility projects, ensuring optimal client service and regulatory compliance throughout all project phases while guiding multidiscip...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Technical Services

$94K - $102K *

Drive your career with a hands-on role coordinating customer security and AI assessments. Collaborate across teams to streamline processes, enhance communication, and ensure timely responses, enabling...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$81K - $122K *

Contribute to financial analysis and reporting, supporting strategic decision-making across departments. Collaborate with stakeholders to enhance budgeting, forecasting, and data management processes...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Advance your career as a Telehealth Clinical Supervisor, providing leadership and clinical oversight to therapists delivering IOP-level care. Collaborate with a dedicated team to enhance patient outco...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$150K - $180K *

Empower the execution of CMC strategies by collaborating across teams to enhance production, streamline operations, and drive commercial success for innovative therapeutics and diagnostics, ensuring a...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Transform your career by leading cross-functional teams to drive drug development strategies. Collaborate with key stakeholders to ensure successful execution of integrated plans, manage risks, and de...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$105K - $108K *

Elevate customer care by managing key accounts, driving performance, and fostering long-term relationships. Collaborate with cross-functional teams to deliver exceptional value, resolve issues, and im...

RemoteRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Healthcare

$142K *

Lead the charge in providing exceptional midwifery care within a dynamic team. Enjoy a balanced schedule with no call, while collaborating with specialists in a supportive environment that prioritizes...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$131K - $177K *

Drive innovative influencer strategies that amplify engagement and shape external narratives, collaborating across departments to elevate corporate reputation and patient storytelling in a highly dyna...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$272K - $340K *

Lead the charge in shaping a global supply chain strategy that ensures seamless delivery of clinical and commercial products. Build a high-performing team and foster partnerships to meet regulatory st...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$170K - $200K *

Reimagine retail leadership as you drive sales growth and develop talent across multiple regions. Lead a team of Regional Directors to enhance patient relationships and execute strategic initiatives...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Drive the month-end close process by ensuring accurate revenue recognition and analysis. Collaborate across departments to produce insightful reports and support financial decision-making while adheri...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$181K - $225K *

Lead the charge in operationalizing complex clinical studies globally, collaborating with cross-functional teams to enhance proposal development and manage global lab relationships, ensuring strategic...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$181K - $225K *

Lead the charge in advancing scientific operations within a dynamic team, driving global lab relationships and supporting complex clinical studies. Collaborate across functions to ensure strategic, op...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$89K - $148K *

Drive your career with impactful consulting in healthcare, enhancing operational efficiency and financial performance for provider organizations through data analysis and project management...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Business Services

$200K - $300K *

Join a team that's driving revenue growth by cultivating strategic accounts and client relationships. Leverage your sales expertise in solution selling and account management to maximize profitability...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Deliver innovative solutions by managing complex programs, ensuring seamless execution and coordination across multiple contracts while leveraging extensive IT expertise and leadership skills to drive...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$225K - $265K *

Transform healthcare interoperability by leading product strategy and market growth. Leverage deep industry insights to enhance payer-provider collaboration, drive operational excellence, and oversee...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Healthcare

$90K - $175K *

Empower mission success by managing COMSEC lifecycle functions, ensuring the security and integrity of communication systems through expert oversight and compliance with national standards...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$150K - $230K *

Drive the promotion of oncology products by building strong relationships with key stakeholders, exceeding performance goals, and ensuring patient access through effective territory management and inn...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.