Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$162K - $195K *

Shape the future of cardiovascular care by driving the launch of a novel cardiac myosin inhibitor. Collaborate with healthcare professionals and internal teams to establish strategic relationships and...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Unlock potential by providing in-home occupational therapy services, evaluating safety, assessing functional needs, and implementing personalized treatment plans to enhance patient independence and qu...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $145K *

Engage in cutting-edge AI development by designing and scaling intelligent applications. Leverage Generative AI and modern tools to enhance productivity and integrate workflows within healthcare platf...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $120K *

Lead the charge in driving operational excellence and strategic enablement across global Inside Sales teams, enhancing commercial effectiveness and delivering exceptional client value through innovati...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Manage implementation projects, ensuring clear ownership and accountability across complex customer engagements while maintaining rigorous oversight of critical paths and deliverables for timely launc...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $125K *

Champion the development of healthcare marketing tools by guiding cross-functional teams through the product lifecycle, driving innovative features and optimizing user experiences to enhance HCP engag...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$66K - $106K *

Lead the charge in conducting medical record reviews and applying clinical judgment to ensure accurate claim payment decisions while supporting fraud investigations and compliance efforts...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$236K - $354K *

Elevate clinical operations by leading global study management, driving strategic vision, and ensuring high-quality trial execution. Collaborate across teams to optimize resources and foster a culture...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$69K - $104K *

Unlock your potential by collaborating with leaders to enhance payor performance, streamline revenue cycle operations, and drive innovation in healthcare. Your expertise will ensure impactful engageme...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$119K - $134K *

Partner with us to enhance patient care by supporting primary care teams remotely. Collaborate with on-site providers to manage patient needs effectively, ensuring seamless communication and coordinat...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Join a dynamic team to oversee clinical research activities, ensuring compliance with regulatory standards and driving site performance. Collaborate with stakeholders to enhance patient safety and dat...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $232K *

Unlock potential by leading legal reviews for promotional and medical materials. Collaborate across teams to ensure compliance and provide practical guidance in a fast-paced environment, supporting pr...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $172K *

Elevate your career by driving growth in national health plan accounts. Leverage your expertise to build relationships, negotiate complex deals, and exceed revenue targets while collaborating with cro...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$108K - $162K *

Join a team that's dedicated to enhancing biomedical service operations. Lead a skilled team of technicians, ensuring high-quality support and customer satisfaction across the Pacific Northwest while...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$135K - $160K *

Champion provider partnerships by leading a dynamic team to drive referrals for interventional treatments across multiple states. Utilize data-driven strategies to enhance performance and build impact...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$285K - $385K *

Lead regulatory due diligence for clinical/commercial assets, assessing risks and strategies for licensing, acquisitions, and partnerships. Collaborate across teams to ensure regulatory integration in...

RemoteRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$149K - $298K *

Lead strategic and operational initiatives for field clinical teams, ensuring compliance and effective trial support for TMVR programs while driving positive patient outcomes and team performance...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $163K *

Transform patient care by providing comprehensive medical services in a dynamic, multidisciplinary environment. Engage with diverse patient populations, ensuring high-quality treatment and education w...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$90K - $163K *

Join a team that's dedicated to providing urgent care services across multiple clinics. As an Advanced Registered Nurse Practitioner, you'll deliver comprehensive patient care, collaborate with multid...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$90K - $163K *

Transform patient care by delivering comprehensive services in a dynamic, multidisciplinary environment. Collaborate with healthcare teams to assess and treat diverse patient populations across multip...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$90K - $163K *

Champion patient care by providing diagnostic and therapeutic services in a dynamic urgent care environment. Collaborate with multidisciplinary teams to ensure comprehensive treatment for diverse pati...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$90K - $163K *

Contribute to patient care in a dynamic environment by providing diagnostic and therapeutic services as an Advanced Registered Nurse Practitioner. Collaborate with multidisciplinary teams to ensure co...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$180K - $200K *

Elevate healthcare technology by owning mobile and web apps that enhance clinician workflows. Drive product direction, prioritize initiatives, and ensure patient safety while leveraging AI to improve...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$155K - $175K *

Champion the field as a Medical Science Liaison, driving prelaunch strategies and fostering relationships with key stakeholders. Leverage clinical insights to educate and influence healthcare professi...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$252K - $315K *

Drive innovation in interventional psychiatry by developing evidence-based programs and protocols. Collaborate with clinical teams to enhance patient outcomes and ensure compliance with regulatory sta...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.