Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$232K - $290K *

Lead the charge in optimizing workforce operations and analytics for multi-condition health care services. Develop strategies for capacity planning, staffing, and analytics to drive efficiency and sup...

United StatesRemote

Reposted 4 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$105K - $124K *

Lead and optimize research intern activities, ensuring alignment with project goals and technical standards. Manage workflows, provide coaching, and conduct hands-on research while supporting the Dire...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Explore advanced revenue analysis and month-end controls to ensure accurate invoicing and financial reporting. Collaborate across functions to resolve discrepancies, mentor junior analysts, and drive...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Join a dynamic team as you manage clinical research sites, ensuring compliance and quality throughout all study phases. Build strong relationships, oversee monitoring activities, and contribute to tea...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $143K *

Engage with healthcare professionals to optimize patient monitoring solutions, ensuring effective implementation and support. Leverage clinical expertise to enhance workflows and deliver exceptional c...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$215K - $240K *

Shape the future of drug development by leading analytical strategies, ensuring compliance and optimization of processes across lifecycle stages, and collaborating with cross-functional teams and exte...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$186K - $233K *

Empower the future of real-world analytics by leading programming activities for observational studies, ensuring high-quality deliverables through collaboration with cross-functional teams and innovat...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$170K - $220K *

Drive product strategy and development to enhance clinician experience, optimizing patient care through innovative solutions and stakeholder collaboration across a nationwide healthcare network...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$225K - $275K *

Lead the Consultant Relations strategy by fostering deep relationships with major consulting firms, ensuring proactive engagement in live deals, and driving business growth through effective account m...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$180K - $215K *

Develop and lead regional strategies to drive product launch success, ensuring alignment with corporate goals. Build a high-performing team, foster customer relationships, and execute data-driven deci...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$175K *

Optimize revenue cycle management by leading a dynamic team to enhance processes, drive automation, and ensure compliance in a fast-paced telehealth environment. Collaborate with cross-functional team...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$102K - $182K *

Lead the design and delivery of innovative clinical sales training programs for Structural Heart, enhancing sales team effectiveness and product knowledge through strategic curriculum development and...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join us to lead the development and execution of clinical study designs, ensuring effective project management and collaboration across teams. Your expertise will drive the success of clinical trials...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Staffing

$245K *

Partner with us to redefine virtual primary care, delivering exceptional patient services through innovative telehealth solutions. Join our dedicated team to enhance health accessibility and effective...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $165K *

Drive the successful transfer of CDI best practices by mentoring client teams, conducting record reviews, and delivering education. Collaborate with healthcare professionals to enhance documentation a...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Business Services

$150K - $175K *

Lead the charge in transforming financial operations while ensuring compliance and accuracy. Collaborate with cross-functional teams to enhance processes, manage audits, and drive strategic initiative...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$102K - $120K *

Join a team that's transforming healthcare analytics by bridging complex data with strategic insights. Leverage your SQL expertise and analytics engineering skills to empower stakeholders and drive va...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $100K *

Join a team that's passionate about transforming complex scientific data into engaging communications. Collaborate with cross-functional experts to deliver high-quality medical content and strategies...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Engage with clients to showcase innovative healthcare solutions, driving sales success through impactful demonstrations and expert guidance. Collaborate with sales teams to address client needs and en...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Analyze performance metrics to empower ACOs in Value-Based Care programs. Collaborate with teams to provide actionable insights, track KPIs, and optimize risk scores, driving data-driven decisions for...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$73K - $125K *

Transform clinical review processes by conducting thorough prepayment and post-payment assessments of inpatient admissions. Leverage your expertise to ensure compliance, support appeals, and enhance q...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Advance the adoption of cutting-edge prostate cancer imaging solutions while leading site activations, enhancing workflows, and ensuring optimal product utilization in the oncology sector, supporting...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$108K - $201K *

Join a dynamic team to drive clinical trials, ensuring compliance and quality. Manage site relationships, monitor trial progress, and collaborate with cross-functional teams to deliver innovative ther...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$81K - $93K *

Empower patients by delivering exceptional care as a Physical Therapist in an outpatient clinic. Collaborate with a supportive team, utilize AI-assisted documentation, and engage in evidence-based pro...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$83K - $114K *

Unlock potential by delivering exceptional patient care in a home health setting. Collaborate with families and healthcare teams to assess, treat, and develop innovative programs, ensuring optimal rec...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.