Explore $100K+ Jobs in Alabama

Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.

Where to Find Professional Jobs in Alabama

Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.

Industries and Roles

High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.

Find the Right Alabama Opportunity

Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.

Advance Your Career in Alabama

Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.

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$83K - $99K *

Lead the charge in delivering expert Flexible Endoscopic Evaluation of Swallowing (FEES) to adults in post-acute care, while collaborating with a dedicated team and contributing to program growth thro...

Decatur, ALRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Unlock potential by leading a dynamic team in a fast-paced urgent care setting. Provide comprehensive patient care across all ages, utilizing your full scope of practice while receiving unmatched supp...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Inspire patient care by leading a dedicated team in a fast-paced urgent care setting. Utilize your full scope of practice to treat diverse patients while receiving unmatched support and training to en...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Elevate patient care by leading a dynamic team in a fast-paced urgent care setting. Utilize your full scope of practice to treat diverse patients, while receiving unmatched support and training to enh...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Lead the charge in providing comprehensive patient care in a fast-paced urgent care setting. Collaborate with a dedicated team to treat diverse patient needs, utilizing your full scope of practice whi...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$93K - $159K *

Advance your career by developing and standardizing Procurement processes that enhance compliance and efficiency. Collaborate with cross-functional teams to create clear documentation and governance p...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$67K - $101K *

Unlock potential by analyzing business trends to enhance customer and sales performance. Collaborate with teams to drive results, manage projects, and ensure accurate reporting, fostering strong relat...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $160K *

Oversee the operational planning and execution of clinical trials, ensuring compliance with regulatory standards while managing cross-functional teams to meet project timelines, budgets, and quality o...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$175K - $185K *

Champion strategic payer engagement to enhance access and reimbursement across a national portfolio. Drive medical policy influence and build relationships with key stakeholders to expand coverage and...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$219K - $277K *

Elevate community oncology practices by driving growth and retention through strategic sales initiatives. Collaborate with cross-functional teams to enhance market presence and deliver tailored soluti...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$160K - $190K *

Pioneer innovative AI solutions to transform biomedical discovery, collaborating with top scientists and engineers to bridge virtual and real-world data, enhancing drug discovery and clinical care pro...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $115K *

Champion clinical excellence by leading and mentoring a dynamic ECM team, ensuring comprehensive patient care and adherence to individualized plans, while collaborating effectively with multidisciplin...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$92K - $138K *

Help us enhance clinical education by delivering expert training and support to healthcare professionals. Drive product adoption and optimize user competencies while fostering strong relationships wit...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$152K - $283K *

Accelerate analytics governance and operations by leading initiatives that enhance decision-making processes, streamline reporting, and modernize workflows across teams, ensuring effective collaborati...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$66K - $116K *

Elevate your career by joining a team that reviews and edits informed consent forms, ensuring compliance with regulatory standards while mentoring new editors and enhancing organizational knowledge in...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$250K - $275K *

Join us to lead clinical operations for a multi-state virtual care team, ensuring high-quality, timely care. This role combines direct patient care, administrative leadership, and strategic oversight...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Lead the charge in providing exceptional patient and family care while managing interdisciplinary teams, ensuring compliance with regulatory standards, and enhancing care quality in a supportive and r...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $140K *

Help us drive the adoption of innovative colorectal cancer screening solutions by effectively engaging healthcare providers through education, consultation, and strategic support in your assigned terr...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$73K - $130K *

Drive the acquisition and usability of clinical data to enhance healthcare outcomes. Collaborate with diverse teams to analyze data gaps, implement integrations, and optimize processes, ensuring timel...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Strategize and lead complex technical analysis to bridge business needs with IT solutions, ensuring compliance and efficiency across enterprise operations while mentoring teams and driving continuous...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$150K - $180K *

Transform clinical research practices by guiding study design and analysis. Collaborate with cross-functional teams to deliver key insights and evidence that drive product innovation in the healthcare...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Take ownership of financial and operational analysis for strategic initiatives, delivering critical insights and reporting to support executive decision-making while driving accuracy and efficiency in...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $215K *

Transform your career by leading regional sales efforts for a groundbreaking product. Drive performance, build a high-performing team, and engage with key healthcare providers in a fast-paced, entrepr...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$204K - $276K *

Lead the charge in global observational research, driving clinical operational strategy and execution. Collaborate with cross-functional teams to ensure quality and efficiency in evidence generation t...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$181K - $291K *

Lead the charge in managing the full systems development lifecycle for enterprise applications, ensuring data quality and integrity while evolving best practices across healthcare operations and suppo...

RemoteRemote

2 days ago

  •   11 - 15 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Alabama?question toggle

    Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.

  • Which Alabama cities have high-paying professional jobs?question toggle

    Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.

  • Are the Alabama jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.

  • How can I find a $100K+ job in Alabama?question toggle

    Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.

  • Do Alabama jobs listed on Ladders require in-person work?question toggle

    Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.