Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.
Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.
High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.
Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.
Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.
Solution Architect, Forward Deployed Architecture (AI Capability Center)
$145K - $170K *
Design innovative AI solutions on Microsoft Azure, bridging business needs and engineering execution. Own the architecture, ensure security, and lead the build process while adapting to evolving proje...
2 weeks ago
Medical Science Liaison, Southeast (Multiple Territories)
$155K - $175K *
Develop trusted relationships with key stakeholders, delivering scientific insights and supporting prelaunch activities. Operate independently in a dynamic environment, influencing adoption through cr...
2 weeks ago
Registered Nurse (RN) Weekend Program - Women's Health and OB (LDRP)
$79K - $118K *
Transform your nursing career by providing compassionate care in a dynamic women's health and OB unit. Collaborate with a dedicated team to ensure safe, therapeutic experiences for patients throughout...
1 week ago
$90K - $140K *
Transform the commissioning process by leading design reviews, functional testing, and site visits. Collaborate with teams to ensure project success and compliance, while managing documentation and tr...
2 weeks ago
$100K - $120K *
Champion healthcare project delivery by managing design and construction lifecycles, ensuring compliance with quality, safety, and budget standards while fostering collaboration among stakeholders to...
3 weeks ago
$130K - $140K *
Shape the future of AI-driven financial advice by designing intuitive, impactful products. Collaborate closely with PMs and engineers to create solutions that enhance user experience and drive results...
6 days ago
Director of Safeguarding and Risk
$130K *
Lead the charge in safeguarding and risk management for behavioral health services, ensuring compliance with regulatory frameworks while driving user satisfaction and engagement through strategic coll...
1 week ago
Senior Oncology Account Manager, Jersey South
$150K - $230K *
Lead the charge in promoting innovative oncology solutions while building strong relationships with healthcare professionals. Drive performance goals and enhance patient access through strategic engag...
1 week ago
$130K - $160K *
Lead all HR functions in a dynamic biotech environment, enhancing employee experience and compliance while driving scalable processes and supporting leadership. Engage with teams to foster growth and...
2 days ago
Clinical Applications Specialist - Dosimetrist (Travelling position)
$123K - $169K *
Unlock your potential by providing expert clinical training and support to customers, ensuring they effectively operate advanced dosimetry equipment. Collaborate with cross-functional teams to enhance...
1 week ago
21GRAMS- Associate Creative Director, Copy
$160K - $180K *
Unlock potential by leading creative engagements across healthcare accounts. Drive innovative campaigns, mentor teams, and manage client relationships while delivering impactful narratives that resona...
3 days ago
Specialty Representative, Psychiatry - Birmingham, AL
$100K - $120K *
Transform customer engagement by executing brand strategies in the field, managing territory effectively, and building strong relationships to maximize sales performance while adhering to compliance a...
1 week ago
Senior Director, Commercial Analytics & Decision Science
$219K - $285K *
Shape and lead a centralized commercial analytics function, transforming complex data into actionable insights. Drive performance measurement, growth identification, and strategic decision-making acro...
1 week ago
Strategy & Operations Manager, In-person (Remote)
$100K - $120K *
Empower the growth of in-person behavioral healthcare by leading strategic operations, enhancing provider acquisition, and ensuring compliance. Drive high-impact initiatives while collaborating across...
4 weeks ago
Manager, CMC Quality, Pulmovant
$110K - $130K *
Lead quality oversight for drug manufacturing, ensuring compliance with cGMPs. Collaborate with vendors on batch record review and product disposition for global clinical programs, thriving in a dynam...
1 week ago
Account Specialist (Burlington, VT)
$160K - $192K *
Collaborate with healthcare providers to drive commercial performance and product adoption. Engage in territory business planning, support product launches, and optimize patient access to innovative t...
1 week ago
$100K - $120K *
Champion medication management services to enhance patient outcomes through collaboration with healthcare professionals, ensuring safe and effective medication use while optimizing therapy for chronic...
1 week ago
$149K - $206K *
Empower your career by delivering exceptional virtual care as you evaluate and treat diverse patient needs, ensuring optimal outcomes through collaboration and quality measures in a dynamic team envir...
Reposted today
$80K - $95K *
Optimize property performance through strategic maintenance leadership, driving safety culture and sustainability. This impactful role necessitates technical expertise and frequent travel to ensure ex...
1 month ago
Cardiovascular Account Specialist - U.S. Sales, Des Moines, IA
$162K - $195K *
Lead the launch of a novel cardiac myosin inhibitor in your territory, driving sales and building strategic relationships with healthcare providers. Collaborate with internal teams to meet patient nee...
2 days ago
$120K - $145K *
Drive the transformation of AI solutions by developing, deploying, and optimizing machine learning models. Collaborate with stakeholders to create innovative applications that enhance patient care whi...
4 days ago
$175K - $190K *
Champion analyst relations by managing strategic engagements and amplifying company narratives. Collaborate cross-functionally to enhance market perception and drive executive influence, ensuring alig...
Reposted 4 weeks ago
Sr Director, Clinical Programs
$129K - $205K *
Innovate clinical outcomes through strategic leadership and cross-functional collaboration, impacting over 200,000 patients. Drive enterprise-wide transformation initiatives, empowering a high-caliber...
Reposted 1 week ago
Senior Manager - Dazodalibep HCP Launch Marketing
$149K - $202K *
Transform the HCP launch landscape by leading innovative marketing initiatives for a groundbreaking treatment in Sjögren's disease. Collaborate cross-functionally to engage healthcare professionals an...
Yesterday
Space Nuclear Systems Engineer
$90K - $140K *
Transform advanced nuclear propulsion systems through innovative analyses and multidisciplinary collaboration. Leverage your expertise in nuclear engineering to support NASA's cutting-edge space react...
4 days ago
What types of $100K+ jobs can I find in Alabama?
Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.
Which Alabama cities have high-paying professional jobs?
Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.
Are the Alabama jobs on Ladders vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.
How can I find a $100K+ job in Alabama?
Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.
Do Alabama jobs listed on Ladders require in-person work?
Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.