Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.
Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.
High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.
Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.
Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.
Senior Medical Director - Oncology
$254K - $382K *
Pioneer innovative clinical strategies as a senior medical leader, driving excellence in study execution and client engagement. Collaborate with cross-functional teams to enhance patient care and oper...
2 days ago
Program Director Internal Medicine & ACMO
$166K - $200K *
Lead the charge in enhancing the Internal Medicine Residency Program through strategic administration, curriculum development, and resident supervision. Collaborate to achieve high standards of qualit...
1 month ago
Director of Risk Adjustment Regulatory Audits
$150K - $206K *
Drive strategic risk management initiatives by leading regulatory audits, enhancing operational processes, and fostering cross-functional collaboration to minimize financial impacts and improve audit...
2 weeks ago
$76K - $148K *
Play a key role in managing clinical trials, ensuring compliance and quality oversight of project deliverables while collaborating with cross-functional teams to meet timelines and budget goals...
Reposted 1 week ago
$110K - $130K *
Transform customer IT service requirements into innovative solutions that enhance loyalty and profitability. Lead technical resources in delivering high-quality financial industry solutions while ensu...
3 weeks ago
Principal Scientist, Process Chemistry
$165K - $185K *
Lead drug substance activities in process chemistry, driving projects from early to late phases. Collaborate with cross-functional teams to ensure successful manufacturing and regulatory submissions...
3 weeks ago
Chief Financial Officer, The AI Access Initiative
$240K - $270K *
Architect the financial backbone of a rapidly scaling AI-focused organization. Collaborate with leadership to design systems, drive compliance, and enable international expansion while leveraging AI f...
3 weeks ago
CNS/Neuroscience, ADHD Territory Sales Representative - Montgomery AL
$115K - $150K *
Join us to achieve ambitious sales goals by driving utilization within your territory, engaging healthcare professionals, and developing strategic business plans. Leverage your expertise in ADHD to cr...
1 month ago
$80K - $95K *
Lead the charge in optimizing therapy services, supervision, and patient care while ensuring compliance with industry standards and operational efficiency in a dynamic healthcare environment...
1 month ago
$80K - $95K *
Empower the CDL program by leading training initiatives, ensuring compliance, and optimizing fleet management. Collaborate with regional leaders to enhance operational efficiency and drive revenue gro...
2 days ago
$80K - $90K *
Lead the visual narrative of client brands by delivering exceptional design solutions across multiple channels. Collaborate with diverse teams to uphold high standards and participate in innovative pr...
Reposted 2 weeks ago
$103K - $176K *
Transform downstream marketing for cutting-edge medical devices. Drive product launches, develop compelling content, analyze market trends, and ensure regulatory compliance across global regions while...
Reposted 3 days ago
$110K - $115K *
Innovate testing strategies and enhance software quality through automated and manual verification. Collaborate across teams to ensure compliance and optimize processes while leveraging AWS and full-s...
3 weeks ago
$125K - $133K *
Champion the development of Generative AI solutions, leading an agile team to enhance products and tooling. Drive AI adoption, mentor engineers, and ensure best practices while collaborating across de...
1 week ago
$250K *
Join a dynamic dental practice as a General Dentist, offering mentorship, a clear development plan, and a path to partnership. Enjoy competitive earnings with a PPO & FFS patient base, focusing on exc...
Yesterday
$125K - $150K *
Lead the charge in designing and delivering AI applications on Snowflake, optimizing data governance and architecture. Collaborate with clients and engineers to transform concepts into scalable, secur...
1 week ago
Medicaid Data & Analytics Specialist
$80K - $95K *
Unlock your potential by analyzing Medicaid data to enhance program performance, quality, and access. Collaborate with diverse teams to develop insights that drive impactful decisions in healthcare an...
2 weeks ago
$105K - $125K *
Transform coding quality and efficiency as a senior expert in radiology coding. Collaborate with cross-functional teams to enhance processes, provide guidance, and drive best practices, ensuring excep...
1 week ago
Psychiatric Nurse Practitioner (Synchronous AHPC) - Remote
$171K - $246K *
Shape the future of mental health care by providing remote psychiatric assessments and treatments. Deliver compassionate support to diverse clients, focusing on adults and adolescents, while collabora...
Reposted yesterday
Account Specialist (Dayton, OH)
$160K - $192K *
Join us to drive commercial performance by engaging healthcare providers, building relationships, and supporting product launches. Collaborate with cross-functional teams to ensure patient access to i...
6 days ago
Senior Oncology Account Manager, Denver
$150K - $230K *
Drive impactful oncology solutions by building strong relationships with key stakeholders, promoting innovative products, and exceeding performance goals in a dynamic biopharma environment. Your exper...
1 week ago
Senior Director Analyst - Digital Workplace - Enterprise Application Architecture and Operations
$172K - $202K *
Innovate within identity and access management by providing expert insights and strategies to clients on best practices in identity governance, privileged access, and AI tools, enhancing cybersecurity...
Reposted 2 weeks ago
Patient and Site Engagement Lead (US/UK)
$90K - $178K *
Transform the patient engagement landscape in clinical trials by developing and delivering strategic support initiatives. Partner with diverse stakeholders to enhance participation and optimize patien...
Reposted 1 week ago
$112K - $128K *
Drive business development for large-scale podcast and broadcast campaigns, fostering client relationships and achieving revenue growth. Collaborate with cross-functional teams to deliver innovative a...
2 weeks ago
$120K - $145K *
Advance healthcare solutions by developing scalable ML systems, collaborating with cross-functional teams, and driving innovative AI methodologies to enhance patient outcomes and optimize operational...
Reposted today
What types of $100K+ jobs can I find in Alabama?
Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.
Which Alabama cities have high-paying professional jobs?
Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.
Are the Alabama jobs on Ladders vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.
How can I find a $100K+ job in Alabama?
Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.
Do Alabama jobs listed on Ladders require in-person work?
Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.