Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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$89K - $134K *

Explore your potential as a key analytical consultant, leveraging data to optimize drug pricing and enhance pharmacy relationships while collaborating across multiple functions to drive strategic grow...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Elevate healthcare through strategic AI product management, driving innovation and lifecycle management of AI solutions. Collaborate cross-functionally to align business objectives with customer needs...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$76K - $119K *

Drive high-quality delivery of Data & AI products by leading cross-functional teams, ensuring alignment with strategic priorities, and optimizing execution processes for maximum business impact...

Conshohocken, PARemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$76K - $119K *

Lead cross-functional Data & AI product teams to ensure efficient delivery, risk management, and alignment with strategic priorities, driving targeted business value through effective execution and co...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Empower your career by leading full-cycle recruiting for technical roles. Collaborate with clients and hiring leaders to shape strategies, source top talent, and drive successful placements in a fast...

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $170K *

Unlock potential by leading hands-on security engineering efforts to modernize cybersecurity for a major federal agency. Collaborate with teams to remediate vulnerabilities and enhance cloud infrastru...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Information Technology

$167K - $196K *

Drive risk mitigation strategies by analyzing account takeover and scam threats. Collaborate cross-functionally to enhance user protection and platform integrity, shaping metrics and prevention tactic...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$114K - $171K *

Join a team that's driving growth in the cardiovascular ASC market by developing strategic relationships and orchestrating complex opportunities across the U.S. Collaborate with diverse stakeholders t...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Business Services

$146K - $229K *

Drive the AI roadmap and deliver secure, scalable solutions that enhance decision-making and streamline workflows. Lead teams from experimentation to production, ensuring measurable business value and...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Join a team that's dedicated to providing technical support and guidance in membrane systems. Collaborate across departments to optimize solutions, assist customers, and enhance product performance th...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Energy & Utilities

$110K - $166K *

Lead the clinical data management process, ensuring quality and compliance from study startup to database lock. Collaborate with teams to develop databases, oversee data integrity, and train personnel...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Analyze and deliver tailored technical solutions, collaborating with teams to implement AI-driven workflows and support complex data migrations, ensuring high-quality service outcomes and stakeholder...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$48K - $115K *

Elevate your career by ensuring compliance with consumer protection laws. Collaborate with teams to assess risks, manage complaints, and enhance processes while developing strong relationships across...

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$48K - $115K *

Analyze consumer protection laws and compliance risks to enhance operational integrity. Collaborate with business units to ensure adherence to regulations, manage complaints, and support compliance tr...

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $120K *

Drive program operations support by managing logistics, personnel processes, and documentation for a dynamic public health initiative. Collaborate with leadership to enhance efficiency and ensure comp...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$93K - $140K *

Elevate cloud security by enhancing standards and implementing risk-based controls across Azure and AWS. Collaborate with teams to secure applications and support AI initiatives, ensuring robust gover...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the charge in enhancing health, safety, and environmental performance across data center construction projects. Collaborate with teams to ensure compliance with OSHA standards and drive continuou...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$89K - $148K *

Drive technical solutions by collaborating with sales teams and customers to enhance industrial communications products. Develop sales strategies, manage customer relationships, and ensure compliance...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$134K - $209K *

Join a team that's redefining data architecture and analytics. Leverage your expertise to drive cloud adoption, modernize data platforms, and influence strategic initiatives that empower data-driven d...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Finance & Insurance

$53K - $132K *

Engineer financial forecasts for clinical trials, collaborating with teams to ensure accuracy and enhance processes. Analyze data, manage stakeholder communications, and drive operational excellence t...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$84K - $129K *

Optimize SCADA systems for electric grid infrastructure. Engage in client projects, design communication systems, and develop automation tools while ensuring compliance with industry standards. Collab...

6 days ago

  •   5 - 7 years exp.  •   Technical Services

$80K - $95K *

Support supplier quality initiatives, ensuring adherence to standards while leading continuous improvement efforts and resolving quality issues to enhance manufacturing productivity and supplier colla...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Champion innovative solutions by providing technical support and product development expertise to customers in the Industrial market. Collaborate across teams to enhance product performance and drive...

Danboro, PARemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$130K - $150K *

Join a dynamic team to lead risk management for large-scale construction projects. Drive risk identification, reporting, and mitigation strategies while collaborating with diverse stakeholders to ensu...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$117K - $201K *

Make your mark as a Principal Scientist, guiding data science and AI initiatives in Immunology. Collaborate with cross-functional teams to innovate and implement data-driven solutions that enhance res...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.