Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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$93K - $138K *

Join a team that's dedicated to enhancing operational efficiency through innovative software solutions. As a key contributor, you'll develop and maintain applications that streamline processes, ensuri...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$80K - $95K *

Join a dynamic team focused on optimizing trading strategies through data analysis and predictive modeling, enhancing market efficiency while driving profitability in a fast-paced environment...

Today

  •   Less than 5 years exp.  •   Energy & Utilities

$110K - $130K *

Lead the charge in developing a sophisticated healthcare SaaS platform by designing, implementing, and maintaining full-stack features that enhance user experience and system performance in a dynamic...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Staffing

$130K - $150K *

Transform your career by leveraging your AWS expertise in a dynamic DevOps role. Collaborate with a hands-on team to enhance infrastructure and streamline development processes while tackling complex...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$110K - $130K *

Elevate your project management career by leading a strategic platform within investor client coverage, enhancing client engagement and driving technology integration across CBRE's commercial real est...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$175K - $200K *

Lead the charge in optimizing biomarker program operations, ensuring seamless sample processing from collection to storage. Collaborate across teams to uphold quality and compliance while driving grow...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$73K - $110K *

Lead impactful projects to enhance Apptio TBM solutions, driving cost transparency, benchmarking, and strategic planning through collaboration with IT and business partners in a fully remote environme...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$184K - $356K *

Transform the future of AI by optimizing generative models for efficiency. Collaborate with cross-functional teams to enhance automated deployment solutions, leveraging cutting-edge technologies in de...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Contribute to impactful consulting services in government pricing, leveraging your expertise to guide clients through compliance, data analysis, and strategic initiatives while leading a collaborative...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$170K - $220K *

Unlock potential by leading the integration of AI tools with PlanetScale databases. Own the developer experience, ensuring seamless functionality across platforms while creating engaging content to sh...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$149K - $235K *

Innovate high-quality AI experiences by collaborating across teams to enhance product quality and user trust. Drive adoption and growth through scalable solutions, while mentoring peers and improving...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$243K - $304K *

Transform the future of data integration by leading product strategy for our database connectors. Collaborate with engineering and sales teams to drive impactful product decisions that enhance analyti...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$124K - $170K *

Lead the charge in innovative software solutions for healthcare, collaborating with diverse teams to enhance patient care and meet customer needs through cutting-edge technology and creative problem-s...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$124K - $170K *

Transform healthcare solutions by leading innovative software development initiatives. Collaborate with diverse teams to implement impactful technologies that enhance patient care and streamline opera...

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$113K - $188K *

Transform data into insights by developing cutting-edge machine learning models. Collaborate with multidisciplinary teams to address complex business needs using advanced analytics, ensuring data-driv...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$100K - $120K *

Empower brand strategies by leading cross-functional teams, managing client relationships, and executing tactical initiatives that align with overall vision. Drive growth and inspire confidence while...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$75K - $140K *

Engage in developing and delivering AI/ML software solutions for national security programs. Collaborate with engineering teams to enhance mission management and data analytics capabilities while supp...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$80K - $95K *

Advance your career by supporting the design and optimization of cutting-edge biomedical devices. Contribute to prototyping and enhance production processes in a collaborative, multidisciplinary envir...

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $140K *

Transform infrastructure and deployment modernization efforts, serving as a technical cornerstone for multiple programs. Drive DevSecOps maturity and cloud adoption while ensuring secure, rapid delive...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$270K - $330K *

Help us drive enterprise growth by owning relationships and closing deals. You'll manage a greenfield territory, navigate complex sales cycles, and build a self-sourced pipeline while positioning our...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Champion the security strategy for a cutting-edge platform, focusing on supply chain security, code scanning, and threat modeling. Collaborate with teams to enhance security practices and drive innova...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$90K - $120K *

Elevate your career by leading clients through the CMMC 2.0 compliance journey. As a key advisor, you'll translate complex regulations into actionable strategies, ensuring audit readiness and security...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Shape the future of business development by driving growth in regulated sectors. Engage clients, manage opportunities, and ensure compliance while collaborating across teams to deliver exceptional ser...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Technical Services

$95K - $115K *

Champion growth by identifying and securing new business opportunities in regulated sectors, focusing on client engagement and compliance to enhance quality and service delivery across manufacturing a...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Technical Services

$100K - $120K *

Transform application deployment by collaborating with teams to streamline processes, enhance automation, and ensure high-quality releases across environments while mentoring junior members and drivin...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.