Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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$110K - $130K *

Lead the development of our observability practice, creating dashboards and alerting systems to ensure uptime and reliability across enterprise tools. Build visibility from scratch, automate processes...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$215K - $235K *

Lead the charge in developing scalable enablement programs that enhance sales performance across customer-facing roles. Utilize your expertise in instructional design and AI to drive adoption, retenti...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$96K - $132K *

Drive impactful technical implementations by managing projects and collaborating with diverse teams to ensure successful deployment of solutions, enhancing client satisfaction and operational efficien...

Pennsylvania, USRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Shape innovative AI solutions by leading the development of scalable machine learning models. Collaborate with cross-functional teams to drive business value and mentor junior data scientists while ad...

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $137K *

Unlock potential by leading strategic client relationships to drive revenue growth and retention. This high-impact role requires expertise in digital media and AI tools, fostering executive partnershi...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Technical Services

$91K - $137K *

Engineer and optimize GPU and AI computing systems to enhance research capabilities in advanced computational workflows. Collaborate across teams to support high-performance infrastructures and ensure...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$91K - $137K *

Pioneer in research computing infrastructure, enabling AI and HPC solutions. Collaborate across teams to design, optimize, and automate innovative systems, supporting advanced research initiatives and...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$204K - $254K *

Lead technical engagements with customers, driving product success through demos, presentations, and collaboration with sales. Contribute to a high-growth team focused on innovative solutions and cust...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Join a team that's shaping the future of geotechnical engineering by overseeing project analysis and design. Contribute your expertise to investigations, data evaluation, and mentoring while ensuring...

Canonsburg, PARemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$137K - $231K *

Empower your career by shaping design systems that enhance user experience. Collaborate with teams to build high-quality, interactive UI across platforms, ensuring accessibility and performance while...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$153K - $254K *

Drive operational excellence across multiple data center facilities, leading a team of managers and technicians. Ensure 100% service uptime while fostering a culture of continuous improvement and coll...

Today

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$69K - $104K *

Unlock potential by joining a dynamic team to enhance employee relations and support management in navigating labor contracts, ensuring fairness and productivity across the organization...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$156K - $275K *

Lead the charge in shaping the technical strategy for reliability and infrastructure. Drive initiatives across teams, design scalable systems, and enhance operational excellence while mentoring engine...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$75K - $95K *

Elevate mobile app acquisition strategies by managing omni-channel paid media campaigns. Collaborate with clients to optimize performance, drive growth, and ensure seamless execution across platforms...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Media

$90K - $150K *

Elevate your career by leading the design and development of innovative web applications and backend services. Collaborate with a dynamic team to enhance customer experiences through AI technologies w...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$130K - $200K *

Drive impactful design and development of front-end features, owning the code from concept to production. Collaborate with teams to establish design systems and set direction for user-centric products...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$120K - $140K *

Shape the future of federal financial operations by driving user adoption and change management for a new tool. Collaborate with stakeholders to enhance user experience, streamline processes, and ensu...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Engage in the development and deployment of innovative cybersecurity solutions, leading efforts to enhance network defense and incident response across a global enterprise while collaborating with mis...

3 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$150K - $180K *

Lead the charge in developing scalable audience solutions by integrating predictive models and data workflows. Collaborate with cross-functional teams to enhance audience activation and ensure reliabl...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Technical Services

$100K - $231K *

Transform healthcare outcomes by leading a team of Clinical Program Consultants to analyze data, optimize clinical programs, and drive strategic initiatives that enhance customer health and reduce cos...

RemoteRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K *

Shape the future of non-profit engagement by leading sales initiatives, driving pipeline growth, and fostering client relationships. Leverage your strategic sales expertise to elevate our impact and a...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$96K - $181K *

Lead the transformation of enterprise technology by architecting scalable GCP solutions and guiding cross-functional teams in developing robust AI-driven applications. Drive innovation through hands-o...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$149K - $239K *

Shape the future of AI solutions by leading cross-functional teams to innovate and implement advanced technologies. Drive client success through strategic partnerships and deliver high-quality, impact...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Business Services

$175K - $210K *

Unlock potential by leading HEOR strategy and AI integration, ensuring project success and client satisfaction. Drive business growth, mentor teams, and influence health policy through innovative rese...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$95K - $140K *

Transform customer expectations into reality by configuring automation systems for high-volume semiconductor environments, ensuring optimal performance of advanced processing tools. Drive improvements...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.