Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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$110K - $130K *

Drive innovation by leveraging your expertise in C/C++, Python, and Linux. Collaborate with a talented team to enhance log management and data visualization tools, while mentoring engineers and making...

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$127K - $171K *

Champion high-impact deployments by leveraging data intelligence and AI to drive governance solutions in regulated industries, serving as a trusted advisor to stakeholders and delivering measurable va...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$132K - $165K *

Drive innovation in oncology diagnostics by leading statistical programming efforts, ensuring data integrity and compliance for clinical trials, while managing a team and collaborating cross-functiona...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive modernization initiatives for cloud-native data architecture, ensuring scalability and reliability for enterprise clients. Collaborate with teams to assess legacy systems and develop effective s...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$95K - $115K *

Unlock potential by designing and implementing a cloud-native architecture. Assess legacy infrastructure, create detailed design documents, and collaborate with engineering to modernize critical data...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$108K - $140K *

Transform talent acquisition by leading a dynamic recruiting team, driving data-informed strategies, and enhancing candidate experiences to meet organizational growth and workforce needs...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$118K - $180K *

Join a dynamic team to analyze solar PV energy yield assessments for utility-scale projects. Lead performance modeling and mentor engineers while expanding expertise across various renewable energy te...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$100K - $120K *

Accelerate growth by driving AI adoption in legal teams. You'll convert inbound leads and build outbound strategies to tap into a vast market, managing demos, trials, and closing deals while collabora...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$180K - $225K *

Transform the claims process by building robust event-driven systems. As a key player, you'll design, implement, and maintain backend services, ensuring reliability and efficiency while mentoring fell...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Business Services

$72K - $115K *

Partner with us to design and validate predictive models that enhance business processes across various domains, leveraging data science techniques to drive insights and improve decision-making within...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $130K *

Drive the design and deployment of secure AI applications in cloud environments, integrating advanced technologies like machine learning and ServiceNow solutions to enhance operational efficiency and...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Optimize clinical data solutions by leading Python programming efforts, enhancing data pipelines, and generating insightful analyses to support clinical research and decision-making across diverse tea...

Blue Bell, PARemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Elevate data privacy standards by leading a comprehensive privacy program. Collaborate across teams to integrate privacy-by-design principles, enhance data governance, and ensure compliance while enab...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$204K - $379K *

Shape the future of Data Science and AI talent strategy, driving enterprise-wide initiatives to attract, develop, and retain critical capabilities while fostering responsible human-AI collaboration ac...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Join our new Data Engineering team to lead business intelligence initiatives, build trusted data models in Snowflake, and deliver impactful reports in Power BI. Collaborate with stakeholders to enhanc...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Join a dynamic team to drive analytics for the Vaccines Business Unit, leveraging insights to influence strategic decisions, enhance marketing effectiveness, and optimize business performance through...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Grow your career with a strategic role in analytics, driving insights and performance for the Vaccines Business Unit. Collaborate across functions to influence decisions and enhance business outcomes...

1 month ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a team that's committed to ensuring quality excellence in high-voltage product innovations. Collaborate across engineering and manufacturing to support NPI projects, driving compliance and proact...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$90K - $120K *

Develop and implement reliability engineering strategies to enhance asset management and operational efficiency. Collaborate with cross-functional teams to optimize maintenance programs and ensure com...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Unlock potential by joining a dynamic team of Solution Consultants, delivering expert guidance on Atlassian products to help clients maximize their investments and achieve strategic outcomes in the Pu...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$210K - $256K *

Transform industry practices by leading large-scale AI and data initiatives, driving business growth and operational excellence within Consumer Products, Retail, and Logistics sectors...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Information Technology

$210K - $256K *

Lead the charge in driving strategic growth and transformation initiatives, leveraging AI and data expertise to elevate Consumer Products, Retail, and Logistics clients through tailored, impactful sol...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Information Technology

$120K - $145K *

Champion innovative database solutions by proactively optimizing performance and guiding clients on cloud strategies. Collaborate with teams to enhance mission-critical systems and ensure seamless ser...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Information Technology

$225K - $265K *

Elevate your career by transforming business workflows into efficient, automated systems. Collaborate with cross-functional teams to implement AI solutions that enhance productivity and drive measurab...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Accelerate your career by designing and optimizing secure, scalable cloud infrastructure. Collaborate with cross-functional teams to enhance operational efficiency and ensure high availability for glo...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Media

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.