Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.
Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.
Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.
Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.
Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.
Executive Director, HEOR Modeling
$175K - $210K *
Unlock potential by leading HEOR strategy and AI integration, ensuring project success and client satisfaction. Drive business growth, mentor teams, and influence health policy through innovative rese...
1 week ago
Senior Associate, Operational Intelligence, Labs
$93K - $138K *
Join a team that's dedicated to enhancing operational efficiency through innovative software solutions. As a key contributor, you'll develop and maintain applications that streamline processes, ensuri...
1 week ago
$110K - $130K *
Lead the charge in developing a sophisticated healthcare SaaS platform by designing, implementing, and maintaining full-stack features that enhance user experience and system performance in a dynamic...
4 weeks ago
$130K - $150K *
Transform your career by leveraging your AWS expertise in a dynamic DevOps role. Collaborate with a hands-on team to enhance infrastructure and streamline development processes while tackling complex...
1 week ago
D&T Sr Project Management Consultant - Talent Community
$110K - $130K *
Elevate your project management career by leading a strategic platform within investor client coverage, enhancing client engagement and driving technology integration across CBRE's commercial real est...
Reposted 2 weeks ago
Operations Director, Biomarker Programs
$175K - $200K *
Lead the charge in optimizing biomarker program operations, ensuring seamless sample processing from collection to storage. Collaborate across teams to uphold quality and compliance while driving grow...
2 weeks ago
IT Business Analyst – Apptio TBM
$73K - $110K *
Lead impactful projects to enhance Apptio TBM solutions, driving cost transparency, benchmarking, and strategic planning through collaboration with IT and business partners in a fully remote environme...
Reposted 3 weeks ago
Senior Deep Learning Software Engineer, Inference and Model Optimization
$184K - $356K *
Transform the future of AI by optimizing generative models for efficiency. Collaborate with cross-functional teams to enhance automated deployment solutions, leveraging cutting-edge technologies in de...
3 weeks ago
$110K - $130K *
Contribute to impactful consulting services in government pricing, leveraging your expertise to guide clients through compliance, data analysis, and strategic initiatives while leading a collaborative...
1 week ago
AI Developer Experience Engineer
$170K - $220K *
Unlock potential by leading the integration of AI tools with PlanetScale databases. Own the developer experience, ensuring seamless functionality across platforms while creating engaging content to sh...
2 weeks ago
$149K - $235K *
Innovate high-quality AI experiences by collaborating across teams to enhance product quality and user trust. Drive adoption and growth through scalable solutions, while mentoring peers and improving...
5 days ago
Staff Product Manager, Databases
$243K - $304K *
Transform the future of data integration by leading product strategy for our database connectors. Collaborate with engineering and sales teams to drive impactful product decisions that enhance analyti...
Yesterday
$124K - $170K *
Lead the charge in innovative software solutions for healthcare, collaborating with diverse teams to enhance patient care and meet customer needs through cutting-edge technology and creative problem-s...
3 weeks ago
$113K - $188K *
Transform data into insights by developing cutting-edge machine learning models. Collaborate with multidisciplinary teams to address complex business needs using advanced analytics, ensuring data-driv...
Reposted 2 weeks ago
$110K - $140K *
Transform infrastructure and deployment modernization efforts, serving as a technical cornerstone for multiple programs. Drive DevSecOps maturity and cloud adoption while ensuring secure, rapid delive...
1 week ago
$270K - $330K *
Help us drive enterprise growth by owning relationships and closing deals. You'll manage a greenfield territory, navigate complex sales cycles, and build a self-sourced pipeline while positioning our...
5 days ago
Staff Product Security Engineer
$150K - $180K *
Champion the security strategy for a cutting-edge platform, focusing on supply chain security, code scanning, and threat modeling. Collaborate with teams to enhance security practices and drive innova...
2 weeks ago
$90K - $120K *
Elevate your career by leading clients through the CMMC 2.0 compliance journey. As a key advisor, you'll translate complex regulations into actionable strategies, ensuring audit readiness and security...
4 weeks ago
Application Deployment Engineer
$100K - $120K *
Transform application deployment by collaborating with teams to streamline processes, enhance automation, and ensure high-quality releases across environments while mentoring junior members and drivin...
Reposted yesterday
Sr. Analyst, Pricing Analytics
$89K - $134K *
Explore your potential as a key analytical consultant, leveraging data to optimize drug pricing and enhance pharmacy relationships while collaborating across multiple functions to drive strategic grow...
1 week ago
$120K - $145K *
Elevate healthcare through strategic AI product management, driving innovation and lifecycle management of AI solutions. Collaborate cross-functionally to align business objectives with customer needs...
2 weeks ago
$150K - $170K *
Unlock potential by leading hands-on security engineering efforts to modernize cybersecurity for a major federal agency. Collaborate with teams to remediate vulnerabilities and enhance cloud infrastru...
2 days ago
$167K - $196K *
Drive risk mitigation strategies by analyzing account takeover and scam threats. Collaborate cross-functionally to enhance user protection and platform integrity, shaping metrics and prevention tactic...
4 weeks ago
ASC Development Leader - Central
$114K - $171K *
Join a team that's driving growth in the cardiovascular ASC market by developing strategic relationships and orchestrating complex opportunities across the U.S. Collaborate with diverse stakeholders t...
5 days ago
$146K - $229K *
Drive the AI roadmap and deliver secure, scalable solutions that enhance decision-making and streamline workflows. Lead teams from experimentation to production, ensuring measurable business value and...
2 days ago
What kinds of $100,000+ jobs are available in Iowa?
Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.
Which Iowa cities have professional jobs listed?
Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.
How can I find the right high-paying job in Iowa?
Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.