Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.
Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.
High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.
Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.
Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.
Average Salary: $106,884
Medical Science Liaison - Ophthalmology/Endocrinology - AL, LA, AR, MS
$156K - $212K *
Transform your career by serving as a scientific liaison, building relationships with key medical experts, and communicating vital information to enhance patient care in the ophthalmology and endocrin...
Today
Senior Mission Systems Engineer
$110K - $130K *
Pioneer innovative solutions by leading complex mission systems engineering projects. Collaborate with diverse teams to manage technical programs from concept to fielding, ensuring successful integrat...
Today
Lead Consultant CDH Implementation
$105K - $149K *
Transform complex Consumer-Directed Health implementations for major employers. Lead strategy, execution, and client engagement while serving as a subject-matter expert to ensure operational excellenc...
Today
Strategic Business Developer 5
$120K - $145K *
Shape the future of avionics sales by leading business development efforts, engaging military and commercial aerospace customers, and driving strategic growth in the Americas through innovative test s...
Today
Director, Technical Product Management
$150K - $180K *
Pioneer the strategy and execution of data platforms and AI products, leading cross-functional teams to enhance commercial life sciences solutions while driving revenue growth and product adoption in...
Reposted today
Product Client Success Manager (First Party Casualty)
$78K - $120K *
Transform claims operations as you empower clients by driving adoption of innovative solutions, optimizing processes, and enhancing business outcomes in the First Party Casualty landscape across vario...
Reposted today
$81K - $110K *
Lead the transformation of patient care by enhancing utilization review processes, ensuring quality documentation, and collaborating with healthcare teams to optimize clinical outcomes and financial p...
Today
Business Process Improvement & Internal Controls Specialist Department of War (DOW)
$61K - $101K *
Unlock potential by joining a dynamic team focused on financial management, internal controls, and fraud risk. Collaborate with federal clients to enhance processes and drive measurable outcomes in au...
Today
$131K - $196K *
Transform user experiences by architecting and deploying high-performing micro-frontends. Collaborate in a fast-paced environment to solve critical challenges and elevate consumer health platforms wit...
Today
Nurse Practitioner - Hospitalist- Nights (SIGN ON BONUS)
$110K - $130K *
Lead the charge in delivering exceptional patient care as a Hospitalist, overseeing comprehensive medical services, collaborating with multidisciplinary teams, and enhancing healthcare outcomes in a d...
Today
Vacation Rental Advisor (Inside Sales)
$55K - $118K *
Champion a consultative sales approach to engage homeowners, guiding them through the partnership process. Leverage inbound leads to drive conversions and manage a dynamic sales pipeline, contributing...
Reposted today
Senior Manager, Virtual Fundraising (Remote)
$80K - $95K *
Join a team that's redefining virtual fundraising by leading innovative campaigns that engage diverse audiences, cultivate partnerships, and drive sustainable revenue growth, all while supporting a me...
Today
Process Development Engineer - Cold End and Packaging
$80K - $95K *
Join a team that's dedicated to optimizing packaging processes and equipment. You'll lead projects, collaborate across departments, and drive continuous improvement initiatives to enhance safety, qual...
Today
Enterprise Architect - Data & Employee Systems (Databricks)
$150K - $170K *
Unlock the potential of enterprise data architecture by designing secure, scalable solutions for employee data using Databricks. Collaborate with cross-functional teams to implement governance, compli...
Today
New Business Sales Executive - Western Territory
$100K - $120K *
Drive revenue growth by cultivating relationships and managing the full-cycle sales process in the healthcare technology sector. Utilize AI-driven solutions to enhance client performance and deliver v...
Today
$80K - $95K *
Join a team that's transforming client websites into growth engines through data-driven conversion rate optimization. Collaborate with cross-functional experts to analyze user behavior, run A/B tests...
Today
$100K - $120K *
Optimize customer engagement by leveraging technical expertise to drive sales, enhance relationships, and expand market share for pneumatic and control systems. Collaborate with teams to deliver tailo...
Today
Senior Manager / Associate Director, Medical Information
$165K - $210K *
Drive the Medical Information strategy for infigratinib, ensuring high-quality, compliant content delivery. Collaborate cross-functionally to support scientific exchange and operational excellence in...
Today
$80K - $95K *
Transform customer relationships and drive revenue growth by managing account strategies, identifying upsell opportunities, and collaborating with cross-functional teams to enhance product adoption an...
Reposted today
Litigation & Compliance Counsel
$163K - $287K *
Lead global litigation management and enhance compliance initiatives while driving strategic legal guidance across pre-litigation matters and ensuring operational alignment with business goals in a dy...
Reposted today
$120K *
Champion the delivery of cross-functional initiatives, aligning teams and strategies to drive measurable business impact while fostering collaboration and continuous improvement in a dynamic environme...
Today
Senior Manufacturing Engineer (Foundry Operations) - Leeds, AL
$90K - $110K *
Grow and optimize manufacturing processes in a dynamic foundry environment. Lead capital projects, ensure compliance with quality standards, and drive continuous improvement initiatives to enhance pro...
Reposted today
Attorney (Litigation) - Birmingham, AL
$90K - $105K *
Champion your legal career by providing strategic counsel and representation in litigation, regulatory compliance, and business transactions. Collaborate with diverse teams to support UAB and its affi...
Today
$120K - $175K *
Pioneer insights at the intersection of Sales, Marketing, and CS by owning and enhancing analytical infrastructure to generate decision-ready insights that drive growth in a dynamic, fast-paced enviro...
Reposted today
Sr. Advisor, Molecular Pharmacology - Neuroscience
$129K - $231K *
Reimagine drug discovery as you lead molecular pharmacology efforts in neuroscience. Collaborate across teams to develop strategies, interpret data, and advance innovative therapies for sleep-wake dis...
Reposted today
What types of $100K+ jobs can I find in Alabama?
Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.
Which Alabama cities have high-paying professional jobs?
Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.
Are the Alabama jobs on Ladders vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.
How can I find a $100K+ job in Alabama?
Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.
Do Alabama jobs listed on Ladders require in-person work?
Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.