Pfizer

Staff Engineer, Sr. Manager

Pfizer$124K — $207K *
Information Technology
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • B.S. in computer science, life science, data science, or similar fields.
  • 6+ years of cloud infrastructure engineering experience focused on IaC deployments.
  • Experience managing scientific computing workloads in an enterprise context.
  • Advanced expertise with AWS and/or GCP, focusing on HPC services.
  • Solid understanding of cloud networking, identity, and security controls.

Responsibilities

  • Design and implement reliable HPC and ML/AI infrastructure in AWS/GCP.
  • Lead the deployment and operation of user-facing and admin HPC platforms.
  • Translate stakeholder requirements into scalable and cost-effective compute environments.
  • Collaborate with HPC specialists to automate deployment processes with IaC.
  • Develop and maintain infrastructure automation using Terraform and CloudFormation.
  • Operationalize containerized solutions through Docker and Kubernetes.
  • Create monitoring solutions to enhance workflow efficiency and user experience.

Benefits

  • 401(k) plan with matching contributions and retirement savings plan.
  • Comprehensive health benefits including medical, prescription drug, dental, and vision coverage.
  • Paid vacation, holidays, personal days, and caregiver/parental leave.
  • Relocation assistance may be available depending on business needs.
Full Job Description

ROLE SUMMARY

Pfizer's committed to the application of computational science in the areas of drug discovery and development. As part of this mission, we have recently embarked on a large-scale migration of our computational infrastructure to cloud.

This role leverages extensive experience in cloud engineering and DevOps and requires a hands-on approach to designing and delivering robust High Performance Computing (HPC) solutions supporting computational workloads across the organization.

We are seeking an experienced individual to drive architecture, infrastructure automation, migration and operational excellence. You will collaborate with HPC engineers and scientific computing specialists to develop scalable cloud native infrastructure that underpins modernization of the scientific computing platform.

ROLE RESPONSIBILITIES


Platform Architecture and Engineering

  • In this role you will design, implement, operate, and own robust and dependable infrastructure for HPC and ML/AI workloads in a cloud environment (AWS/GCP).

  • Lead containerization, deployment, and operation of user- and admin-facing HPC platforms (Slurm, Open On Demand, Prometheus/Grafana, batch and distributed computing platforms) across cloud environments.

  • Translate stakeholder input into robust, high-performance, scalable, cost effective computing platforms.

  • Partner with HPC specialists (engineers, administrators, and users) to capture institutional knowledge and manual processes in IaC workflows, transforming ad-hoc deployment practices into reproducible, version-controlled, automated procedures.

Automation and DevOps

  • Develop and maintain infrastructure automation using IaC tools like Terraform and CloudFormation to ensure repeatable environment provisioning and scaling.

  • Create reusable Terraform modules. Develop and enforce standards. Be a driver for implementing and maintaining all cloud infrastructure using IaC tools.

  • Operationalize containerized solutions using Docker and Kubernetes.

  • Own the full lifecycle of infrastructure management, from provisioning to operations, support, updating, and teardown of production computing platforms.

  • Perform troubleshooting, system analysis, and benchmarking to resolve issues and maintain a high-performance environment.

Monitoring and Reliability

  • Develop and maintain monitoring, logging, and alerting for the infrastructure (e.g., CloudWatch, Prometheus/Grafana).

  • Design new dashboards, workflows, and utilities to improve observability, cost monitoring, workload efficiency, user, or administration experience.

  • Document architecture, deployment processes, and operational procedures.

  • Partner closely with team members to support delivery of scientific computing services including user support, Linux administration, operations, job scheduling, application management, and resource optimization.

BASIC QUALIFICATIONS

  • B.S. in computer science, life science, data science or similar fields.

  • 6+ years of experience in cloud infrastructure engineering with a proven track record of developing and supporting robust IaC deployments.

  • Experience managing scientific computing workloads in an enterprise environment.

  • Advanced experience with at least one of AWS and GCP, including knowledge of core compute and storage services relevant to HPC.

  • Solid understanding of cloud networking, identity, and security controls.

PREFERRED QUALIFICATIONS

  • Prior experience with HPC deployment utilities including AWS ParallelCluster, AWS Parallel Computing Services, and Google Cloud Cluster Toolkit.

  • Proficiency with distributed computing environments, especially EKS/GKE/Kubernetes.

  • Familiarity with HPC environments, job schedulers (Slurm), HPC application containers (Docker, Singularity, Apptainer) and NVIDIA GPU computing.


Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

Occasional international travel for team meetings and conferences.

OTHER JOB DETAILS:

  • Last Date to Apply for Job: April 14th, 2026

  • Work Location Assignment: Hybrid. Must be able to work from assigned Pfizer office 2-3 days per week, or as needed by the business

The annual base salary for this position ranges from $124,400.00 to $207,400.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Information & Business Tech

About Pfizer

Hospira, Inc. is the provider of injectable drugs and infusion technologies. Through its broad, integrated portfolio, Hospira is uniquely positioned to Advance Wellness™ by improving patient and caregiver safety while reducing healthcare costs. The company is headquartered in Lake Forest, Ill., and has approximately 16,000 employees.

Pfizer Careers

Joining Pfizer’s global team offers more than just job opportunities; it’s a chance to be a part of a company that leads with science and innovates for better health. As a leading biopharmaceutical company, Pfizer is at the forefront of transforming lives through innovation, leadership, and diversity. Work You’ll Do At Pfizer, you will collaborate with some of the brightest minds in the industry, engaging in work that enhances global health and saves lives. Our culture thrives on intellectual curiosity, professional growth, and inclusivity, making every day a learning opportunity. Here, your skills will be honed, your professional acumen will be expanded, and you will be part of a team that values the power of diverse insights to drive success. Pfizer’s Leadership and Growth Lead and innovate with Pfizer, where we value the growth of each employee. Our leadership is committed to providing employees with the training and resources needed to excel in their careers. Pfizer offers a variety of career paths, including roles in research, marketing, finance, technology, and more, each offering a unique blend of challenges and rewards. Internship and Employment Opportunities Start your career with Pfizer through our internship programs or dive straight into a full-time position. We are hiring individuals who are passionate about healthcare and who seek to make a difference in the world. Our internships provide invaluable industry experience, networking opportunities, and a potential pathway to full-time employment. Benefits and Culture Pfizer is dedicated to fostering a workplace where all employees feel valued and can achieve their full potential. We offer competitive benefits packages that support the health, well-being, and financial security of our employees and their families. At Pfizer, you’ll find a culture that encourages collaboration, innovation, and continuous learning. Join Our Team Explore the numerous job opportunities at Pfizer by searching open positions that match your skills and interests. We look for driven, curious, and innovative team players who are ready to advance their careers in a transformative company. Stay Connected Keep up to date with career tips, insider perspectives, and industry-leading insights you can put to use today—all from the people who work here. Personalize your subscription to receive job alerts, latest news, and insider tips tailored to your preferences. Discover the exciting and rewarding career opportunities that await at Pfizer. Interview and Resume Tips Prepare for your future with Pfizer by utilizing our resources for resume building and interview preparation. We provide guidance on how to effectively showcase your skills and experiences to align with the needs of a position at Pfizer. Our goal is to help you succeed in securing a role that suits your professional goals and personal growth aspirations. Pfizer: A Place Where You Can Make a Difference Every position at Pfizer contributes to our mission of making the world a healthier place. Whether through direct patient care, research innovation, or corporate roles that support our operations, your work will have global impact. Join us in our journey to change lives—explore Pfizer careers today.
Learn more about Pfizer
Size
79,000 employees
Market Cap
$285.9 billion
Industry
Net Income
$9.6 billion
Founded
1849
5 Year Trend
+9%
Revenue
$41.9 billion
NASDAQ

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