Job DescriptionThis scientist has a proven track record of cellular and molecular proteomics, analytical chemistry and/or biochemistry to play a key supporting role in the MS-based proteomics group in the Exploratory Biomarkers team. The scientist will contribute to the development of proteomic workflows using robotics and automated liquid handlers with the outcome to accelerating and alleviating the manual-intensive aspects of sample prep increasing throughput and depth. The candidate will apply new and established workflows to biological systems and various sample types (tissues, biofluids and cells) for biomarker discovery and mechanism of action studies.
Essential Duties and Responsibilities
- Contribute to innovative therapeutic platforms and apply cutting-edge proteomic technologies for disease profiling and biomarker discovery
- Generate proteomic datasets for disease profiling and mechanism of action studies
- Assist in instrument troubleshooting, maintenance and repairs
- Work with cross-functional teams and across different therapeutic areas and academic collaborators on these projects
QualificationsRequired Education, Experience, Skills and Certifications- MS and 3+ years or equivalent, BS with 5+ years relevant lab experience in biochemistry, proteomics, analytical chemistry, or related field in academic, pharma or biotech industry, or PhD with 0-1 years postgraduate experience
- Hands-on experience with proteomics, minimum 1 year of hands-on lab experience
- Quick to learn new systems and processes, with a focus on continuous improvement
- Strong organizational and communication skills with a high attention to detail
- Able to conduct experiments and analyze data independently
- Strong time management skills
- Good team player
- Skilled at managing multiple priorities and building strong cross-functional relationships
- Able to help maintain various lab instruments
- Proficiency in Microsoft Office (PowerPoint, Excel, Word)
- Authorization to work in the country indefinitely without sponsorship
Preferred Education, Experience, Skills and Certifications- Experience using an electronic lab notebook
- Cell Culture experience
- Experience communicating results in small group meetings and/or in reports
- Sample preparation of limited tissue samples with Ultrasensitive proteomics
- Hands-on targeted proteomic approaches
- Hands-on co-immunoprecipitations, affinity-based protein profiling, chemoproteomics
- Analysis of proteomic data sets, coding experience in R or Python
Additional InformationThe position is full-time, Monday-Friday, 8:00am-5:00pm, with overtime as needed. Candidates living within a commutable range of Cambridge, MA are encouraged to apply.
- Compensation: $90,000-105,000/year
- Excellent full time benefits including comprehensive medical coverage, dental, and vision options
- Life and disability insurance
- 401(k) with company match
- Paid vacation and holidays
