Dyne Therapeutics

Director, US Commercial Enablement

Dyne Therapeutics$188K — $235K *
Pharmaceuticals & Biotech
11 - 15 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree; advanced degree preferred
  • 12+ years in biotech, pharma, or life sciences with field sales experience
  • Experience in launch readiness, especially in rare disease-related therapies
  • Proven project management and leadership experience
  • Strategic mindset with execution capabilities
  • Familiarity with CRM and BI tools like Snowflake and Boomi
  • Strong analytical, problem-solving, and communication skills

Responsibilities

  • Lead design and administration of incentive compensation programs
  • Develop compensation models and manage reporting systems
  • Serve as business owner for CRM platforms, enhancing field engagement
  • Optimize business intelligence tools for data accuracy and effectiveness
  • Implement scalable processes for field operations
  • Coordinate cross-functional planning and national meetings
  • Drive collaboration across commercial and operational teams

Benefits

  • Professional development opportunities
  • Collaborative work environment
  • Engagement in impactful projects
  • Opportunity to influence strategic initiatives
  • Work based in Waltham, MA
Full Job Description
Role Summary

The Director, US Commercial Enablement drives strategic commercial enablement initiatives and builds foundational tools, processes, and capabilities to support business growth and launch readiness. The Director establishes and optimizes field enablement infrastructure, including incentive compensation, CRM platforms, and business intelligence tools, while ensuring alignment across cross-functional stakeholders. This role enhances field effectiveness, builds scalable processes, and promotes operational excellence with a patient-first mindset.

This position is based in Waltham, MA

Primary Responsibilities Include:

Incentive Compensation and Performance Programs
  • Leads planning, design, and administration of incentive compensation and bonus programs across commercial, medical, and patient services teams
  • Develops plan design models, manages payouts, and delivers monthly and quarterly reporting
  • Maintains plan documentation, tracking systems, and performance monitoring processes
  • Conducts regular performance reviews with stakeholders to optimize program effectiveness
  • Partners with field teams to build account planning tools
  • Leads recognition programs, including Circle of Excellence and associated planning

Commercial Systems, Tools, and Analytics
  • Serves as commercial business owner for CRM platforms (e.g., Veeva), translating field needs into system enhancements
  • Partners with IT and stakeholders to implement and optimize CRM and data solutions
  • Owns business intelligence reporting tools and ensures data accuracy through quality control processes
  • Supports reporting platforms across market access and patient services
  • Optimizes field enablement tools and materials to improve productivity and effectiveness

Field Operations and Infrastructure
  • Designs and implements fleet program aligned with business needs and industry benchmarks
  • Maintains and updates fleet policies in collaboration with Compliance, HR, Finance, and Field Leadership
  • Builds scalable processes to support field teams and commercial operations

Cross-Functional Planning and Execution
  • Leads coordination of national, regional, and headquarters meetings in partnership with Marketing and Commercial teams
  • Drives cross-functional planning across Sales, Marketing, Market Access, Advanced Analytics, Patient Services, Finance, and IT
  • Ensures alignment and readiness to support commercial launch and execution
  • Strengthens collaboration and communication across teams

Education and Skills Requirements:
  • Bachelor's degree; advanced degree preferred
  • 12+ years of experience in biotech, pharmaceutical, or life sciences industry, including field sales, sales leadership, field operations, or consulting experience supporting commercial organizations
  • Demonstrated experience supporting or leading launch readiness, ideally in rare disease, neuromuscular, neurodegenerative, or neurodevelopmental therapies
  • Strong leadership and project management experience, including managing vendors and scaling commercial infrastructure
  • Strategic mindset with ability to execute and deliver results
  • Experience with commercial technology platforms and data environments (e.g., CRM, BI tools, Snowflake, Boomi, SP/SIP, HUB data)
  • Strong analytical and problem-solving skills
  • Excellent written and verbal communication skills, including ability to present to senior leadership
  • Demonstrated ability to collaborate effectively across cross-functional stakeholders

#LI-Onsite

MA Pay Range

$188,000-$235,000 USD

The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills.

The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements. Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload.

About Dyne Therapeutics

Dyne Therapeutics is a biotechnology company that is focused on developing therapies for patients with genetically driven muscle diseases. The company is developing a platform that is designed to deliver nucleic acids to muscle tissue. Dyne's lead product candidate is DYN101, which is a treatment for patients with myotonic dystrophy type 1 (DM1). DM1 is a genetic disorder that affects the muscles and other body systems. DYN101 is designed to reduce the levels of toxic RNA that are produced by the mutated gene that causes DM1. The company was founded in 2018 and is headquartered in Cambridge, Massachusetts.
Learn more about Dyne Therapeutics
Size
70 employees
Market Cap
$633.4 million
Industry
NASDAQ

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