Find professional opportunities in West Virginia with salaries of $100,000 or more on Ladders. Browse vetted openings across the Mountain State, from established employers in Charleston and Huntington to opportunities in Morgantown, Wheeling, and beyond. Whether you’re pursuing your next leadership role or bringing specialized expertise to a growing organization, discover jobs that match your experience and career goals.
West Virginia’s professional job market spans healthcare, energy, engineering, technology, finance, education, and management. Employers seek experienced clinicians and healthcare leaders, engineers and energy specialists, technology professionals, executives, and other seasoned talent. Available roles and salary ranges vary by employer, location, and qualifications.
Explore openings in urban centers such as Charleston, Huntington, and Morgantown, as well as roles throughout the state. Some positions may offer remote or hybrid work, while others require an on-site presence. Review each listing for its location, work arrangement, compensation, and requirements.
Use Ladders to search vetted jobs with salaries of at least $100,000. Filter opportunities by title, industry, and location, then compare responsibilities and qualifications to identify roles aligned with your background. Keep your resume current and tailor your application to highlight the expertise and measurable results employers value.
Average Salary: $124,673
Staff Software Engineer: Database Reliability Engineering
$120K - $145K *
Champion the modernization of enterprise data tiers by automating database reliability engineering across hybrid cloud environments, enhancing performance, and ensuring high availability for mission-c...
2 days ago
Business Development Manager, Industrial
$95K - $115K *
Elevate your career by driving growth through strategic business development in the industrial sector. Collaborate with enterprise clients, build relationships, and close deals while leveraging innova...
2 days ago
Forward Deployed Full Stack Engineer (Active Secret Clearance)
$120K - $145K *
Drive impactful software solutions by embedding with clients, transforming ambiguous needs into deployable features across secure environments. Collaborate closely with users and stakeholders to deliv...
2 days ago
$120K - $135K *
Elevate our proposal management efforts by leading strategic submissions, fostering collaboration among teams, and enhancing our pursuit capabilities to secure high-value projects that improve infrast...
2 days ago
Vice President, Presales & Solutioning - Remote, United States
$175K - $210K *
Lead a dynamic team to drive presales and solution architecture for enterprise transformation, shaping innovative technology solutions and enhancing client engagements while fostering a high-performin...
2 days ago
$125K - $150K *
Lead the charge in enterprise sales by hunting new logos within the Life Sciences sector. Build relationships with Salesforce partners to enhance co-selling opportunities while managing your own pipel...
2 days ago
Cloud Infrastructure Architect - Remote
$120K - $160K *
Drive the design and management of cloud infrastructure, ensuring secure, scalable systems that align IT operations with business goals. Lead initiatives in automation and DevSecOps to enhance operati...
2 days ago
$96K - $101K *
Empower domestic workers by leading impactful research initiatives that inform advocacy and policy development. Drive strategic research agendas, mentor a dedicated team, and collaborate with diverse...
2 days ago
Senior Actuarial Analyst: Commercial Lines - Remote
$92K - $135K *
Grow your career with a dynamic role providing actuarial support for commercial lines, managing projects, analyzing market trends, and ensuring compliance while advancing your actuarial expertise thro...
2 days ago
Director, Enterprise CRM Delivery - Remote, United States
$150K - $180K *
Manage delivery leadership for life sciences CRM transformation programs, ensuring high-quality implementations and migrations. Collaborate with cross-functional teams to meet client expectations and...
2 days ago
$80K - $104K *
Lead the charge in managing building infrastructure projects, ensuring timely coordination and compliance with standards. Collaborate with tenants, contractors, and management to deliver quality servi...
Reposted 2 days ago
Commercial Sales and Project Support
$130K - $150K *
Elevate project success by managing the lifecycle of commercial sales initiatives. Collaborate across teams to ensure accurate documentation, financial oversight, and timely invoicing, driving efficie...
2 days ago
$132K - $153K *
Join a team that's redefining care management by leading strategic initiatives in utilization and appeals processes. Drive high-quality, cost-effective care while ensuring compliance and fostering a c...
2 days ago
Customer Success Director (Oracle Focused)
$100K - $125K *
Engage with strategic Oracle customers to drive success through relationship management, implementation guidance, and value realization. Champion customer outcomes and optimize their journey with Redw...
2 days ago
$120K - $150K *
Elevate pediatric dental care by joining our collaborative team, where you'll provide exceptional treatment to children in a supportive, high-volume practice. Enjoy a fulfilling role that fosters last...
2 days ago
$120K - $144K *
Join a team that's dedicated to providing exceptional dental care to children. This role offers the chance to build lasting relationships in a supportive, multi-doctor environment while utilizing mode...
2 days ago
$200K - $240K *
Optimize global sales strategies to drive revenue growth and market leadership. Lead the transformation of sales functions into a cohesive, customer-centric organization, ensuring alignment with long...
2 days ago
$120K - $145K *
Champion the development of clinical operations by managing a network of providers, establishing policies, and enhancing quality programs. Collaborate with leadership to ensure operational excellence...
2 days ago
STRIDES Laboratory and Diagnostics Advisor, Outbreak Preparedness and Response
$89K - $120K *
Drive initiatives to expand and strengthen laboratory systems for outbreak response and public health, ensuring alignment with national policies and international standards while providing technical l...
Reposted 2 days ago
Sr Manager, Clinical Data Management
$143K - $185K *
Unlock potential by leading clinical data management for innovative cell therapy studies. Collaborate cross-functionally to ensure data integrity and compliance while managing teams and external partn...
Reposted 2 days ago
$100K - $130K *
Lead on-site management for industrial projects, ensuring safety, efficiency, and client satisfaction. Oversee crew operations, manage resources, and drive project completion while maintaining quality...
2 days ago
Customer Success Manager (Higher Education)
$80K - $97K *
Unlock your potential as you drive customer success in Higher Education. Build trusted relationships, manage strategic accounts, and ensure satisfaction through effective collaboration and tailored su...
2 days ago
$110K - $130K *
Accelerate the deployment of innovative manufacturing processes for oncology products, ensuring compliance and collaboration across teams. Lead technology transfers and facility readiness to enhance p...
Reposted 2 days ago
Senior Medical Science Liaison - Western US
$180K - $190K *
Join a team that's dedicated to advancing precision medicine by leveraging AI to provide cutting-edge educational support and scientific expertise on cancer biomarker tests while engaging key opinion...
Reposted 2 days ago
$113K - $140K *
Champion the reliability and performance of critical systems, driving architecture evolution and incident response. Collaborate with a skilled team across AWS and Azure, ensuring security and scalabil...
2 days ago
What types of high-paying jobs are available in West Virginia?
Openings can include positions in healthcare, energy, engineering, technology, finance, education, and executive management. Availability changes over time, so browse current listings for the latest opportunities.
Are West Virginia jobs on Ladders vetted?
Ladders features vetted professional jobs paying $100,000 or more. Check each listing for details about the employer, compensation, responsibilities, and qualifications.
Which West Virginia cities have professional job opportunities?
Opportunities may be found in Charleston, Huntington, Morgantown, Wheeling, and other communities across the state. Search by location to see current openings.
Can I find remote jobs based in West Virginia?
Some listings may offer remote or hybrid work, while others are location-based. Review the work arrangement specified in each job posting.
How can I find a $100,000-plus job in West Virginia?
Search West Virginia listings on Ladders, filter by location or role, and review positions that meet your salary and experience goals. Tailor your resume to the qualifications and results emphasized in each posting.