Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Senior Electrical Engineer | Kansas City, MO
$95K - $115K *
Champion innovative electrical design solutions for complex projects, collaborating with multidisciplinary teams to enhance healthcare and institutional environments while ensuring high-performance, e...
1 week ago
Senior Manager, Web Strategy & Experience
$125K - $150K *
Drive the web strategy and optimization for multiple domains, enhancing user engagement and conversion rates. Lead a dynamic team to implement data-driven improvements and ensure a cohesive online pre...
Reposted 1 week ago
Senior Manager, Web Strategy & Experience
$110K - $130K *
Transform our web presence by owning strategy and optimization across multiple domains, enhancing user engagement, driving conversions, and managing a high-performing team to create a seamless and eff...
Reposted 1 week ago
Senior Manager, Solutions Engineering - State, Local, Educational (SLED) Top 1200
$172K - $215K *
Lead and develop a national Solutions Engineering team, driving technical wins and ensuring effective deployment of drone technology in public safety. Collaborate with sales and product teams to enhan...
4 weeks ago
$85K - $95K *
Partner with us to deliver tailored solutions and technical expertise, enhancing customer engagement through product demonstrations and RFP management while collaborating across teams to drive innovat...
3 days ago
Staff Product Manager, Mobile Application
$140K - $157K *
Empower users by driving the vision and strategy for our mobile app, enhancing customer acquisition and retention through innovative features and seamless experiences. Collaborate with cross-functiona...
3 days ago
Senior Product Manager | Mobile
$160K - $200K *
Join a team that's redefining mobile solutions for professionals. You'll lead product strategy, prototype with AI, and drive impactful changes across our mobile apps, ensuring seamless experiences for...
Yesterday
$72K - $100K *
Join our dynamic team as a Sr. Credit Analyst, owning the underwriting cycle from application review to decision-making. Leverage your analytical skills to enhance credit processes and contribute to a...
2 weeks ago
$110K - $130K *
Join our team to validate and enhance data migration processes through comprehensive testing, ensuring quality and performance in a dynamic Agile environment. Your expertise will drive successful syst...
3 weeks ago
Senior/Lead Product Manager, Integrations
$120K - $145K *
Elevate integrations by leading the product roadmap, focusing on API-first solutions and enhancing developer experience to drive scalability and monetization across the platform...
1 week ago
Senior Site Reliability Engineer
$130K - $155K *
Transform our platform by enhancing performance and reliability as a Senior Site Reliability Engineer. Collaborate with teams to optimize Ruby on Rails applications, leverage AI for operational effici...
4 weeks ago
$145K - $157K *
Transform space operations by leveraging Kubernetes to deliver resilient solutions. Collaborate within an Agile framework to enhance software deployment, ensuring optimal performance and security for...
2 weeks ago
$75K - $105K *
Champion project success by collaborating with teams to develop technical strategies, manage client communications, and ensure profitable project execution across diverse industrial applications...
4 days ago
Project Engineer - Industrial Automation
$140K *
Design innovative control systems and automation solutions, managing project scope, budget, and vendor relations. Collaborate with teams to ensure successful commissioning and provide ongoing technica...
3 weeks ago
$171K - $214K *
Join us to lead the design and oversight of complex models driving customer lifetime value. Collaborate with engineers and business teams to enhance decision-making across marketing, finance, and prod...
Reposted 1 week ago
Director, BI & Data Engineering
$165K - $195K *
Lead the charge in developing and managing a robust Enterprise Data Warehouse on Databricks. Drive BI solutions, mentor a team, and ensure data quality while collaborating across departments to enhanc...
4 days ago
$190K - $220K *
Shape the future of product design by leading a dynamic team, setting vision, and enhancing user experiences across platforms while driving design excellence and mentoring talent...
4 days ago
$108K - $149K *
Shape the future of technical marketing by crafting compelling narratives that engage practitioners and influencers, driving curiosity and interest in cutting-edge cybersecurity solutions across our i...
2 weeks ago
Senior Product Manager, Commitments
$135K - $160K *
Lead the strategy for the Commitments product, enhancing customer compliance tracking through AI. Collaborate with cross-functional teams to drive adoption and deliver impactful solutions that address...
5 days ago
Data Scientist, Enterprise Analytics
$86K - $176K *
Unlock potential by leveraging data science to drive strategic insights and performance across sales and finance. Collaborate with teams to enhance decision-making through advanced analytics, machine...
4 days ago
Senior Platform Infrastructure Engineer - USA Remote
$135K - $150K *
Transform cloud infrastructure at scale while designing robust pipelines and practices. Oversee the integration of security, compliance, and operational standards to support enterprise-wide AI-driven...
Reposted 4 weeks ago
Staff Machine Learning Engineer(Platform - Identity)
$218K - $256K *
Lead the end-to-end execution of ML systems for identity verification, ensuring the integrity of millions of accounts through advanced models and cross-team collaboration, while mentoring engineers an...
Reposted 6 days ago
Enterprise MarTech Program Manager
$120K - $130K *
Manage enterprise-wide MarTech programs, aligning cross-functional teams to drive B2C marketing initiatives. Translate business priorities into actionable plans, ensuring effective collaboration and m...
3 weeks ago
Sr. Security Operations Manager
$172K - $269K *
Lead and modernize global security operations, managing a distributed team while enhancing detection strategies and incident response. Drive AI integration for efficiency and ensure accountability thr...
Reposted today
$108K - $130K *
Lead the charge in engineering excellence, overseeing project management and technical solutions for gas utility infrastructure. Drive compliance, staff development, and innovative practices to ensure...
Today
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.