Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$208K - $312K *
Join a team that's redefining cloud storage solutions. As a Product Manager, you'll drive the vision and strategy for our storage portfolio, ensuring seamless integration and performance across applic...
2 weeks ago
Lead Project Manager (AI Initiatives) - Remote
$110K - $130K *
Champion the execution of AI initiatives across the enterprise by overseeing project governance, planning, and cross-functional coordination, driving effective delivery from concept to measurable outc...
Reposted 1 week ago
$122K - $261K *
Elevate employee experiences by leading digital transformation initiatives, providing strategic guidance, and implementing scalable solutions across enterprise environments to enhance productivity and...
1 week ago
$120K - $145K *
Explore the opportunity to manage and evolve complex multi-prem platform architecture. Collaborate with engineering teams, ensuring operational excellence across diverse environments while leveraging...
Reposted 2 weeks ago
Senior Product Manager, Data Products
$130K - $155K *
Elevate data product experiences by defining metrics that drive value for Mural. Collaborate across teams to shape insights, enhance reporting, and ensure data integrity, empowering organizations to m...
1 week ago
Manager, Enterprise Sales | DX
$158K - $248K *
Transform sales performance by coaching a team of Enterprise Account Executives, driving revenue growth, and institutionalizing effective sales processes while fostering a culture of continuous learni...
1 week ago
$88K - $105K *
Join a team that's dedicated to driving engineering excellence and innovation. Oversee a skilled group of engineers, manage budgets, and ensure timely project completion while fostering collaboration...
Reposted 3 days ago
$184K - $314K *
Elevate executive recruiting by leading VP-level searches, advising C-suite leaders, and shaping talent strategies. Drive high-impact hiring decisions while managing multiple confidential searches in...
Today
$120K - $145K *
Join a team that's redefining media pricing and transactions by creating and executing customer-focused product strategies, enhancing user engagement, and navigating a complex media landscape through...
Reposted 3 weeks ago
Senior GTM Strategy & Operations Manager, Mid-Late Sales Funnel
$135K - $160K *
Advance the operational strategy for the mid-to-late sales funnel through effective deal management, cross-functional collaboration, and process evolution. Shape workflows and drive efficiency to enha...
Reposted today
Application Packaging Engineer
$116K - $122K *
Deliver reliable application packaging solutions for a large federal IT environment. Collaborate with stakeholders to gather requirements and ensure seamless deployment across thousands of endpoints...
1 week ago
Digital Product Manager - Control Integration Engineering
$120K - $193K *
Accelerate progress at the intersection of security and technology by leading integration product management for enterprise security capabilities across multiple business units, ensuring streamlined a...
4 days ago
$120K - $130K *
Champion the modernization of data processes by designing and maintaining robust data pipelines in Azure. Collaborate with stakeholders to ensure accurate data integration and support enterprise data...
1 week ago
Senior DevSecOps Engineer (TS/SCI)
$140K - $200K *
Lead the charge in optimizing our OpenShift platform, leveraging your DevSecOps expertise to enhance operations and support national security efforts. Collaborate with multidisciplinary teams to craft...
Today
Sales Development Manager - Attribute™
$110K - $130K *
Lead and scale a high-performing global SDR team, optimizing outbound strategies and driving pipeline through innovative coaching and performance tracking in a dynamic, fast-paced environment...
Reposted today
$110K - $130K *
Unlock developer potential by creating engaging content, organizing events, and fostering community connections. Collaborate with cross-functional teams to enhance user experience and advocate for dev...
2 weeks ago
Senior Manager - Technical Implementation & Value Realization
$135K - $150K *
Advance your career by leading complex enterprise implementations, driving customer adoption, and ensuring measurable value realization. Collaborate with cross-functional teams to operationalize solut...
3 weeks ago
$150K - $180K *
Shape the future of enterprise-scale cybersecurity by leading vulnerability management initiatives. Drive program strategy, enhance client relationships, and mentor teams to achieve measurable risk re...
Reposted 4 weeks ago
Product Marketing Manager, Launches & Core Platform
$115K - $125K *
Lead the charge in product marketing by owning go-to-market launches and creating engaging content. Collaborate with teams to translate technical improvements into customer benefits, ensuring successf...
1 week ago
AI Deployment Engineer/Manager
$80K - $95K *
Champion the deployment of cutting-edge AI systems in diverse environments. Collaborate with teams to ensure seamless installation and operation of hardware and software, while providing exceptional c...
1 week ago
$135K - $160K *
Lead a dynamic engineering team to innovate and deliver backend solutions, enhancing our technology's reach. Engage hands-on in coding and architecture while mentoring others, ensuring high-quality so...
Reposted 4 days ago
$95K - $115K *
Champion innovative solutions in a dynamic, remote environment, driving sales strategy and product development for public safety agencies. Collaborate with teams to deliver impactful presentations and...
6 days ago
Senior Product Manager, Marketing Platform
$162K - $224K *
Champion the evolution of marketing technology by managing the roadmap and execution of innovative tools that enhance borrower engagement and streamline campaign processes, leveraging AI and data to d...
Today
$135K - $220K *
Lead the charge in enhancing security tooling for compliance and cybersecurity. Collaborate with engineering teams to automate security checks, ensuring a robust pipeline that balances speed and secur...
1 week ago
$110K - $130K *
Accelerate your career by designing and developing innovative software solutions. Collaborate with cross-functional teams to tackle complex challenges and enhance mission objectives in a dynamic, Agil...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.