Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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$160K - $230K *

Elevate your career by owning the infrastructure and security of a multi-environment platform. Collaborate with leadership to build and operate systems that support critical government operations and...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Provide expert technical support and solutions to enhance customer success with Mastercam products, collaborating with teams to optimize workflows and drive product improvements in the West region...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$100K - $125K *

Lead innovative design solutions as a Senior Design Engineer, transforming client needs into actionable broadcast system designs. Collaborate with global teams, mentor junior engineers, and ensure pro...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$98K - $144K *

Shape innovative full-stack applications by collaborating with teams, mentoring junior developers, and ensuring alignment with business needs and industry standards. Drive solutions using C# and Angul...

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$98K - $144K *

Elevate your career by developing scalable full-stack applications, collaborating with stakeholders, and mentoring junior teams. Drive innovation through modern technologies while enhancing existing s...

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$135K - $160K *

Champion growth by leading a dynamic team of sales engineers, collaborating with sales leadership to drive technical strategies and enhance customer value in the Enterprise sector. Stay ahead of indus...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$145K - $193K *

Architect and enhance robust software solutions for player registration, identity verification, and compliance. Collaborate across teams to optimize performance, scalability, and security while mentor...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$80K - $95K *

Join a team that's dedicated to enhancing enterprise software solutions by investigating complex issues, collaborating with engineering, and delivering reliable customer support to drive product impro...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$104K - $166K *

Unlock the potential of automation by developing end-to-end solutions using Ansible, Python, and RESTful APIs. Collaborate with cross-functional teams to enhance operational efficiency and support a s...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$80K - $96K *

Join a team that's driving automation and digital transformation in government and defense. Leverage your RPA expertise to design, develop, and deploy innovative solutions while collaborating with div...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Lead the design and implementation of innovative temporary power generation and energy systems. Drive multidisciplinary engineering efforts to deliver safe, efficient electrical solutions while mentor...

6 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$108K - $130K *

Lead the charge in architecting enterprise application integration solutions. Collaborate with Agile teams to create technical specifications, establish coding standards, and mentor developers while d...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $171K *

Transform client success by delivering tailored support and strategic insights, ensuring seamless onboarding and ongoing engagement with our innovative platform. Leverage your expertise in energy engi...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Join a team that's redefining employee payment solutions. As an Implementation Manager, oversee the deployment of our SaaS product for diverse clients, ensuring successful integrations and fostering s...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Unlock potential by driving impactful marketing strategies for a key partnership. Collaborate across teams to create campaigns, manage events, and analyze performance, directly influencing revenue gro...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$286K - $315K *

Join a team that drives growth by managing strategic accounts and fostering relationships. You'll coordinate with various teams to ensure successful adoption of solutions within large enterprises whil...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$126K - $137K *

Join a team that's transforming Supply Chain Analytics by developing innovative software solutions. Leverage your full-stack expertise to create user-friendly applications that integrate AI capabiliti...

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$126K - $137K *

Champion innovative software solutions by developing and optimizing full-stack applications in the CAD/CAE domain, leveraging Java, Angular, and cloud technologies to enhance user experience and perfo...

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$140K - $170K *

Lead the charge in integrating AI capabilities across enterprise platforms, enhancing digital services for Veterans. Collaborate with teams to implement innovative solutions while ensuring security an...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$117K - $173K *

Join us to design and implement advanced cloud data solutions, optimizing data pipelines and architectures. Collaborate with teams to modernize systems and enhance real-time reporting, leveraging cutt...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Join a dynamic team to lead connectivity projects for leased data centers, ensuring compliance with standards and managing cross-functional collaboration from site assessment to operational handoff. D...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$92K - $136K *

Help us drive customer success by owning and optimizing digital engagement programs. You'll lead strategy, build automated journeys, and analyze performance to enhance customer experiences and ensure...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Information Technology

$85K - $106K *

Empower clients by leading innovative paid search strategies across diverse categories. Collaborate with cross-functional teams to drive performance, optimize campaigns, and connect search tactics to...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$194K - $259K *

Innovate data solutions by building robust models and pipelines, translating business needs into technical specifications, and mentoring junior engineers to enhance data engineering practices and code...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Business Services

$100K - $145K *

Join a dynamic team to ensure seamless network connectivity for dock deployments. Collaborate with IT teams, troubleshoot connectivity issues, and enhance customer confidence through effective communi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.