Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$100K - $110K *
Elevate your career by joining a dynamic Technical Operations team focused on cloud-native infrastructure and Kubernetes. Collaborate across teams to enhance platform reliability and drive operational...
Yesterday
Staff Process Engineer - Consumer & Life Solutions (Kansas City)
$88K - $105K *
Elevate process engineering designs from concept to completion across diverse sectors, ensuring project alignment with budget and client needs while collaborating with multidisciplinary teams througho...
Yesterday
Director, Product Management | Applied AI
$160K - $190K *
Lead and develop a team of Product Managers to drive AI-powered product strategy, governance, and investment decisions. Shape the organization's AI capabilities while ensuring responsible AI practices...
2 weeks ago
Senior Product Manager - Inventory
$159K - $273K *
Shape the future of home listings by driving supply growth and enhancing buyer experiences. Lead AI-driven initiatives to optimize inventory presentation and engagement, ensuring Redfin remains the go...
2 weeks ago
Lead Specialist, Technical Architect
$150K - $160K *
Partner with us to shape the quality strategy for a leading exam development platform. Leverage your expertise to guide multiple Agile teams, enhance automation practices, and ensure high standards ac...
Reposted today
$112K - $135K *
Elevate your career by designing and implementing cloud infrastructure solutions in Azure. Collaborate with teams to automate deployments, optimize CI/CD pipelines, and leverage AI tools for enhanced...
4 days ago
Senior Technical Program Manager
$123K - $218K *
Take ownership of complex project delivery across multiple teams, ensuring timely execution of high-stakes initiatives. Collaborate with engineers and researchers to optimize project management practi...
5 days ago
$194K - $246K *
Drive transformative user experiences in grocery shopping by leading design across platforms. Collaborate across teams to enhance personalization, implement AI solutions, and create compelling narrati...
Reposted 4 days ago
$100K - $120K *
Drive project success by managing financial planning, stakeholder relationships, and full-lifecycle oversight. Utilize advanced project management tools to ensure effective communication and adaptabil...
4 weeks ago
$110K - $130K *
Empower project success by managing financial coordination, stakeholder relationships, and full-lifecycle oversight. Drive effective communication and risk management while adapting to changing priori...
4 weeks ago
$125K - $150K *
Drive customer success by leading enterprise engagements and deploying AI solutions. Collaborate with cross-functional teams to ensure operational impact and long-term partnerships, enhancing efficien...
3 weeks ago
Applied Research Scientist, World Model
$185K - $312K *
Engineer the future of home shopping by developing a foundational AI model that integrates market dynamics, consumer behavior, and economic factors to enhance user experience and decision-making in re...
2 weeks ago
$94K - $126K *
Join a team that's driving growth in military and government sectors by developing strategic sales capabilities and fostering strong customer relationships to maximize territory potential and ensure l...
1 week ago
$97K - $109K *
Join a team that's redefining customer engagement by providing technical expertise and tailored solutions during the pre-sales process. Collaborate with sales and services to ensure seamless transitio...
2 weeks ago
Staff Application Engineer - AI Enablement
$112K - $165K *
Champion data quality by executing data mapping and integration tasks within PLM systems. Collaborate with teams to develop reusable components and ensure adherence to enterprise architecture standard...
4 days ago
Senior Client Engagement Manager
$100K - $120K *
Empower your career by leading client engagement for a major modernization project. Collaborate with stakeholders, resolve issues, and drive project delivery in a dynamic environment focused on govern...
4 days ago
Enterprise Sales Engineer - New York
$120K - $145K *
Partner with us to drive technical sales success by leveraging your expertise in cloud and container technologies. Cultivate relationships, conduct demos, and secure wins while collaborating with our...
1 week ago
$90K - $110K *
Explore innovative front-end development in a dynamic team, delivering cutting-edge geospatial solutions. Collaborate in an Agile environment, leveraging modern technologies to enhance mission-focused...
2 weeks ago
$108K - $130K *
Bring your expertise to lead a dynamic team of systems engineers, balancing hands-on technical execution with strategic management. Drive innovative solutions in identity management, endpoint security...
5 days ago
Senior Manager - AI Product Management
$130K - $155K *
Drive the strategic direction of AI products, leading a team to deliver scalable, reusable AI capabilities that enhance customer experiences and enterprise workflows while ensuring responsible AI prac...
1 week ago
Senior Product Marketing Manager - Outbound
$110K - $130K *
Unlock potential by driving impactful product launches through cross-functional collaboration and strategic messaging. Engage directly with clients and teams to enhance market presence, adoption, and...
Reposted 2 weeks ago
$90K - $100K *
Unlock potential by delivering innovative robotic solutions, ensuring seamless integration and operational success for customers. Collaborate, troubleshoot, and enhance system performance while provid...
2 weeks ago
$110K - $130K *
Take ownership of the product lifecycle for a cutting-edge SaaS platform, leading cross-functional teams to define strategy, prioritize features, and ensure successful product launches that align with...
Reposted today
Director, Software Engineering - Motion Technology
$150K - $180K *
Drive the strategy and development of innovative motion technology solutions, overseeing globally distributed engineering teams to deliver high-quality software. Collaborate with stakeholders to align...
1 week ago
$110K - $130K *
Optimize electrical designs and support construction projects across various sectors. Collaborate with teams to ensure compliance with codes and standards while delivering innovative solutions for ind...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.