Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$110K - $130K *

Unlock potential by joining a dynamic team of Solution Consultants, delivering expert guidance on Atlassian products to help clients maximize their investments and achieve strategic outcomes in the Pu...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Optimize technology solutions for supply chain operations by leading full-stack engineering efforts. Drive development, mentor teams, and align projects with business goals to deliver scalable web and...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K - $170K *

Shape the future of enterprise infrastructure by leading design, implementation, and optimization of systems. Drive automation, enhance security, and mentor junior staff while collaborating on strateg...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Empower strategic financial decisions by analyzing investments, market opportunities, and capital allocation. Collaborate with C-suite executives to drive growth and optimize resource allocation while...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Transportation

$166K - $249K *

Shape the future of AI in healthcare by defining and executing a strategic roadmap that integrates intelligent solutions into clinical workflows, ensuring safety and efficiency while collaborating wit...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $159K *

Join our team to drive software design assurance for innovative cloud-based and AI/ML systems. Collaborate with cross-functional teams to ensure compliance with global regulations and enhance product...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$104K - $191K *

Accelerate progress at the forefront of cybersecurity by driving AI and automation initiatives. Collaborate with security teams to identify opportunities, coach on new tools, and enhance organizationa...

Des Moines, IARemote

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$148K - $178K *

Transform municipal services by leading complex projects and optimizing the Accela Civic Platform. Drive innovation in permitting and development processes while ensuring compliance and enhancing cust...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $200K *

Transform the security landscape by leading corporate security and compliance initiatives. Own identity infrastructure, manage vendor relationships, and ensure customer trust while implementing robust...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$90K - $110K *

Join a team that's dedicated to delivering successful large-scale projects. Oversee all phases from planning to execution, ensuring timely completion and budget adherence while fostering strong custom...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Lead the charge in driving operational excellence through innovative improvements, leveraging Lean and Six Sigma methodologies to enhance manufacturing efficiency, reduce waste, and optimize processes...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$108K - $130K *

Empower enterprise infrastructures by designing automated workflows for secure, scalable network management. Utilize advanced scripting and automation to optimize systems while leveraging your experti...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Transform the future of AI-driven infrastructure products by leading strategic growth initiatives, collaborating closely with Marketing and Engineering, and influencing key product decisions for optim...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$108K - $129K *

Champion innovative manufacturing solutions by leading design feedback, quoting, and DFM initiatives. Collaborate cross-functionally to enhance product manufacturability and mentor engineers, driving...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$146K - $229K *

Unlock potential by leading a high-accountability engineering team to architect and deliver innovative data products, enabling analytics and AI while fostering a culture of quality and collaboration a...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Shape the future of engineering by leading innovative structural projects, managing client relationships, and mentoring technical staff. Drive business growth in eastern Iowa and surrounding areas wit...

Reposted today

  •   11 - 15 years exp.  •   Technical Services

$95K - $115K *

Transform the structural engineering landscape by managing projects that enhance client relationships and drive business growth while delivering high-quality engineering solutions and mentoring emergi...

Reposted today

  •   11 - 15 years exp.  •   Technical Services

$93K - $125K *

Join a dynamic team as a technical resource, enhancing enterprise applications and infrastructure services. Drive operational excellence, support cross-functional initiatives, and ensure reliable, sec...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$75K - $106K *

Manage high-quality technical support for corporate users, ensuring seamless operation of Windows and macOS devices, Microsoft 365, and endpoint technologies. Drive improvements in support processes a...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Food & Beverages

$95K - $120K *

Champion quality assurance in GIS software by developing test plans, validating data, and ensuring reliability for Army geospatial applications. Collaborate with experts to enhance automated testing p...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$143K - $169K *

Lead the transition to a modern, AI-native ITSM platform, enhancing service management across teams. Drive employee-centric design, streamline workflows, and ensure seamless integration while maintain...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$185K - $210K *

Lead the charge in transforming TMC implementations by defining processes, configuring platforms, and training teams to ensure seamless transitions and rapid go-lives across multiple projects simultan...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$126K - $150K *

Pioneer the transformation of tax technology and processes, driving strategic initiatives to enhance operational efficiency, compliance, and user experience through automation and data-driven solution...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$86K - $118K *

Take ownership of hardware operations by installing, configuring, and troubleshooting technical equipment. Collaborate with teams to maintain infrastructure and ensure optimal performance in a dynamic...

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$160K - $190K *

Transform user engagement by owning product roadmaps, collaborating cross-functionally, and leveraging data to drive impactful solutions. Engage with customers to identify opportunities and validate h...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.