Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

$204K - $290K *

Manage the Resilience Engineering team to enhance system reliability through production load testing and chaos engineering while fostering a proactive safety culture across engineering practices...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$107K - $195K *

Lead the charge in developing advanced platforms that automate operations and enhance AI-driven interactions. This hands-on role combines technical leadership with coding, mentoring, and ensuring comp...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$172K - $229K *

Build and lead a team to enhance platform testing and support for core infrastructure. Drive technical direction, manage incident response, and ensure software quality across systems, while collaborat...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Transportation

$181K - $213K *

Transform product-led growth by crafting data-driven strategies, enhancing customer experiences with AI, and driving account expansion through collaboration and experimentation across teams...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Drive system reliability and scalability as a Senior Site Reliability Engineer, focusing on automation and collaboration with software teams to enhance performance and maintain service objectives acro...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $120K *

Unlock potential by delivering actionable insights through data analysis, visualization, and reporting. Collaborate across departments to enhance decision-making with automated dashboards and performa...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$83K - $222K *

Drive innovation by delivering high-quality web applications and interactive dashboards. Collaborate with cross-functional teams to integrate AI capabilities and build resilient APIs in a fast-paced...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $160K *

Shape the future of global merchandising technology by leading engineering efforts, driving modernization, and ensuring high-quality delivery across diverse platforms. Collaborate with teams to implem...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$115K - $275K *

Manage the delivery of GPU clusters for AI workloads by coordinating teams across engineering, networking, and operations. Develop strategies, manage risks, and ensure timely, quality launches to scal...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$196K - $222K *

Unlock innovative AI solutions by designing and building autonomous coding agents that enhance operational efficiency and integrate seamlessly with existing systems, driving measurable improvements in...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Empower users by creating intuitive video editing tools and features. Collaborate on innovative UI designs and enhance existing functionalities, ensuring a seamless experience for editors transitionin...

RemoteRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Information Technology

$190K - $215K *

Engage in the design and development of robust full-stack solutions, guiding teams in secure engineering practices while integrating innovative technologies in a federal environment. Drive impactful c...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Information Technology

$130K - $160K *

Lead the end-to-end customer onboarding process, managing cross-functional teams to ensure timely delivery and value realization. Collaborate with customers to provide expert guidance and drive succes...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Join a dynamic team to drive technical success and adoption across enterprise accounts. Leverage your expertise in project management and technical execution to enhance deployment health and fuel acco...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Drive innovation by designing async backend systems that integrate AI seamlessly, enabling scalable solutions for millions of businesses. Collaborate with a dynamic team to transform concepts into pro...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$175K - $225K *

Transform data engineering practices by architecting scalable platforms, driving reliability, and mentoring teams. Lead cross-functional initiatives to enhance data governance and leverage AI tools fo...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$123K - $166K *

Join a team that's dedicated to enhancing cloud platform reliability and security. As a Platform Engineer, you'll leverage your expertise in Kubernetes and CI/CD to build and maintain robust infrastru...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$225K - $281K *

Lead detection and response strategy, building systems and automations to enhance security. Collaborate with teams to set standards, mentor engineers, and manage complex incidents, ensuring effective...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$146K - $206K *

Contribute to the development of a scalable platform ensuring liquidity for effective loan origination and vendor payments. Engage with cross-functional teams to design and implement user-friendly sys...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$145K - $185K *

Lead and inspire engineering teams to deliver high-quality digital products, ensuring alignment with business priorities while fostering a culture of collaboration and continuous improvement in a dyna...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $150K *

Join our dynamic team as a Senior Engine Programmer, where you'll design and optimize core game engine systems, collaborating with external developers to enhance performance across multiple games. You...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$186K - $218K *

Drive the development and operation of backend services for a subscription product, enhancing user experience and retention through scalable solutions and cross-functional collaboration...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$168K - $285K *

Drive product strategy for tenant scale and unified deployment across platforms, collaborating with engineering and product teams to enhance scalability and customer experience while mentoring peers a...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Join a team that's dedicated to building and enhancing robust full-stack solutions. You'll take ownership of features from design to deployment, collaborating with engineers to deliver high-quality, s...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Staffing

$120K - $145K *

Pioneer the development of secure platform capabilities for enterprise clients, collaborating across teams to define product scope, manage complex requirements, and ensure successful delivery in highl...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.