Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$120K - $125K *

Drive your career with a dynamic role focused on developing, testing, and implementing innovative applications. Collaborate with teams to analyze requirements, ensure quality, and document processes w...

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$94K - $176K *

Drive innovation in document processing by leading high-impact projects, shaping architecture, and optimizing performance in a queue-driven pipeline. Collaborate across teams to enhance AI products an...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Media

$95K - $115K *

Join a dynamic team to develop innovative embedded software solutions, ensuring high-quality design and timely delivery for transportation-related applications. Collaborate across functions to achieve...

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$75K - $140K *

Join a team that's shaping the future of space technology by developing innovative software solutions for complex systems, optimizing satellite constellations, and enhancing space domain awareness thr...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$75K - $140K *

Innovate solutions by designing, developing, and testing software for critical military systems. Collaborate in Agile teams to enhance communication capabilities while applying analytical skills acros...

2 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$153K - $166K *

Join a team that's shaping the future of AI governance in software development. As a Senior Engineer, you'll design policies and tools that ensure safe, effective use of AI coding agents, empowering d...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$170K - $200K *

Advance backend solutions and frontend features, collaborating across teams to build scalable systems and AI integrations, driving product growth from conception to execution...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $187K *

Lead the development of innovative software solutions using Python and AWS. Collaborate with cross-functional teams to create scalable applications that leverage AI/ML technologies, ensuring high perf...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$188K - $296K *

Advance the development of innovative software solutions, integrating scalable and secure applications while mentoring teams. Drive technical leadership and ensure quality assurance throughout the sof...

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Hospitality & Recreation

$466K - $500K+*

Accelerate progress at the forefront of ML infrastructure, collaborating with cross-functional teams to design and implement user-centric solutions that enhance model development and deployment for di...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$140K - $165K *

Join a dynamic team as you lead the design and development of complex software systems. Drive technical direction, mentor peers, and ensure high-quality, scalable solutions that align with business go...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $160K *

Elevate your career as a Staff Software Engineer, leading full-stack development in a dynamic team. Design, build, and support healthcare applications while ensuring data security and compliance in a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Drive your career forward by designing and developing full-stack web applications. Collaborate with teams to enhance functionality and performance while modernizing critical business solutions in a dy...

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $204K *

Drive innovative software solutions for advanced missile targeting and strike planning. Collaborate within a dynamic team to enhance mission-critical applications, ensuring quality and efficiency in d...

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$207K - $300K *

Drive innovation by leading engineering teams to develop large-scale infrastructure and systems. Oversee project deployment globally while fostering collaboration and technical excellence across multi...

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$200K - $260K *

Transform software delivery as a Technical Program Manager, overseeing quarterly releases from planning to execution. Collaborate cross-functionally to ensure quality, manage risks, and drive critical...

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$155K - $200K *

Drive the development and management of software teams, fostering a culture of trust and continuous learning while ensuring timely delivery of high-quality software products through Agile methodologie...

2 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$85K - $145K *

Develop innovative full stack applications to enhance legal operations and compliance. Collaborate with cross-functional teams to deliver secure, scalable solutions using modern technologies and cloud...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$108K - $130K *

Build and maintain scalable backend services in a microservices architecture, leveraging modern programming languages and technologies to enhance critical banking domains and support product developme...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $145K *

Join a team that's building and scaling a data and analytics platform to enhance clinical AI performance. Collaborate with cross-functional teams to create actionable insights and drive improvements i...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$250K - $300K *

Accelerate progress at a forward-thinking company by leading a dynamic engineering team, fostering a culture of excellence while delivering innovative product features and driving technical growth. Co...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $210K *

Collaborate with cross-functional teams to design and deliver full-stack features, enhancing code quality and mentoring junior engineers while owning projects from inception to deployment in a dynamic...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$71K - $97K *

Optimize the reliability and performance of automated warehouse systems. Engage in hands-on troubleshooting, maintenance, and technical execution to ensure optimal system uptime in a fast-paced produc...

4 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$154K - $260K *

Innovate and drive technical strategy for AI-powered products at scale. Empower teams to build transformative software solutions, oversee complex projects, and deliver exceptional results that reshape...

RemoteRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $115K *

Join a dynamic team to develop innovative software solutions for medical devices, collaborating across disciplines from design to release while enhancing user experience and meeting clinical needs in...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.