Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$128K - $153K *

Join a team that's shaping the future of technology by delivering impactful software solutions. Collaborate on innovative projects, optimize data operations, and enhance user experiences while support...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Lead a dynamic team of software engineers to enhance data import systems, ensuring efficient document processing and integration. Drive technical direction, improve engineering practices, and foster a...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$188K - $235K *

Develop AI-powered systems from concept to production, collaborating with clients to identify needs, prototype solutions, and ensure quality. Engage closely with users to iterate and enhance product f...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$125K - $135K *

Innovate and lead as a Senior Software Engineer, driving full-stack solutions and mentoring talent. Collaborate with teams to enhance software processes, ensuring high-quality delivery and technical e...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$220K - $270K *

Drive innovation as you design and maintain user-mode components for accelerators, ensuring seamless integration with compilers and kernel drivers. Collaborate with cross-functional teams to deliver r...

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $200K *

Transform your career by leading innovative software solutions, guiding AI-driven development, and ensuring high-quality deliverables. Collaborate with cross-functional teams to shape the technical la...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$166K - $242K *

Deliver secure, reliable backend systems that enhance user experiences across products. Own projects from design to deployment, collaborating with cross-functional teams to balance security and usabil...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$135K - $160K *

Lead the charge in solving critical engineering challenges, driving technical direction, and fostering team growth. Collaborate across departments to enhance systems, ensuring reliability and innovati...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$124K - $170K *

Lead the charge in innovative software solutions for healthcare, collaborating with diverse teams to enhance patient care and meet customer needs through cutting-edge technology and creative problem-s...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$124K - $170K *

Transform healthcare solutions by leading innovative software development initiatives. Collaborate with diverse teams to implement impactful technologies that enhance patient care and streamline opera...

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$165K - $260K *

Drive the development of an intelligent content delivery network, optimizing web performance through cutting-edge infrastructure and AI. Collaborate with a lean team to transform complex problems into...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$120K - $145K *

Elevate your career by managing technical programs across global engineering teams. Drive alignment, enhance decision-making, and leverage AI to optimize workflows while supporting senior leadership i...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Unlock the potential of autonomous vehicles by developing motion planning components. Collaborate across teams to design, implement, and test high-performance software that enhances on-road performanc...

1 week ago

  •   Less than 5 years exp.  •   Transportation

$190K - $267K *

Unlock potential by designing and building innovative developer tools that enhance software development processes. Collaborate across teams to improve reliability, usability, and scalability of servic...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Media

$148K - $201K *

Lead the charge in enhancing software-defined networking capabilities by assessing, modernizing, and securing codebases. Collaborate with engineers and stakeholders to ensure robust, maintainable soft...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$82K - $105K *

Develop innovative firmware for camera products, collaborating globally to enhance performance and serviceability. Engage in Agile practices, mentor junior engineers, and support lifecycle management...

5 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$120K - $145K *

Deliver innovative solutions as a Senior C++ Engineer, driving development in the gaming industry. Collaborate in a dynamic, remote environment, leveraging your expertise in C++ and Windows systems to...

Reposted today

  •   8 - 10 years exp.  •   Staffing

$115K *

Empower our mobile development team by fostering collaboration, mentoring engineers, and implementing best practices. Drive high-quality software delivery while ensuring seamless integration with web...

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$153K - $200K *

Transform user experiences by building and enhancing core communication interfaces. Collaborate with cross-functional teams to deliver impactful features and take ownership of projects from inception...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$140K - $160K *

Elevate your career by joining a dynamic team as a Data Engineer, owning end-to-end data systems and driving platform modernization. You'll improve data reliability and work closely with cross-functio...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Join a team that's shaping the future of backend storage solutions on AWS. You'll design, build, and optimize scalable systems, ensuring high performance and reliability while collaborating with cross...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Join a dynamic team as a Senior Software Engineer, designing and scaling innovative healthcare solutions. Drive technical excellence, mentor peers, and collaborate cross-functionally to enhance patien...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Unlock potential by leading the design and development of scalable, data-driven healthcare solutions. Collaborate with cross-functional teams to enhance patient discharge processes while driving engin...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$135K - $160K *

Architect robust Kubernetes solutions to enhance cloud infrastructure. Drive multi-cloud initiatives and implement cell-based architecture for scalable, reliable services. Join a team dedicated to bui...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$118K - $139K *

Develop innovative software solutions by leveraging your expertise in modern frameworks and agile practices. Collaborate with cross-functional teams to enhance system performance and scalability while...

Pittsburgh, PARemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.