Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$122K - $205K *

Empower the public sector by modernizing software development with AI-driven solutions. Drive strategic initiatives, cultivate executive relationships, and navigate procurement processes to deliver im...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$142K - $186K *

Pioneer a data-driven culture by designing scalable ELT pipelines and analytics models. Collaborate across teams to ensure product data integrity and empower stakeholders with self-service insights, d...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $160K *

Elevate cloud security and reliability by leading DevOps practices across teams. You'll optimize AWS and GCP environments, enhance CI/CD pipelines, and ensure cost-effective engineering tools, driving...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$220K - $270K *

Unlock potential by guiding application security strategies across diverse product landscapes. In this senior technical role, you'll influence architecture, mentor teams, and enhance security processe...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $95K *

Lead the charge in civil engineering as a senior authority, guiding depot management and ensuring compliance with design criteria, contractual obligations, and project execution for facility construct...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$162K - $259K *

Lead the charge in owning the software release cycle, ensuring operational readiness and alignment across engineering and product teams. Drive strategy and metrics for successful deployments as we sca...

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$139K - $235K *

Transform customer infrastructure management by owning the product vision and roadmap for a key control plane. Collaborate with engineering to enhance user experience and operational efficiency, drivi...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Transform product operations by enhancing collaboration across teams and streamlining the launch processes. Utilize data-driven insights and AI to identify bottlenecks and drive efficiency, ensuring s...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Legal & Accounting

$110K - $130K *

Innovate within a dynamic team to design and develop cutting-edge web applications, leveraging modern technologies and cloud solutions to enhance user experience and drive business success...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$87K - $128K *

Join a cutting-edge team to develop semiconductor processes, drive hands-on experiments, and collaborate with engineering to enhance equipment performance and innovation in a fast-paced manufacturing...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$130K - $160K *

Unlock potential by leading mobile app development, shaping user experiences, and driving technical direction in a fast-paced environment. Collaborate with cross-functional teams to deliver intuitive...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$154K - $226K *

Oversee the end-to-end deployment of ML and AI models, ensuring reliable production capabilities. Manage infrastructure, monitor performance, and drive operational excellence while collaborating acros...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Elevate your career by architecting scalable analytics systems and AI-driven workflows that empower decision-making across our enterprise SaaS business, paving the way for innovation and growth in a d...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Technical Services

$89K - $115K *

Shape innovative software solutions by designing, developing, and maintaining robust applications. Collaborate with cross-functional teams to enhance user experience and optimize application performan...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $155K *

Lead cross-functional teams to drive enterprise modernization through AI solutions. Oversee complex implementations, ensuring alignment across technical and business stakeholders while delivering meas...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$69K - $101K *

Champion the reliability of automated systems by providing expert technical support, troubleshooting complex issues, and collaborating cross-functionally to ensure operational excellence and seamless...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Accelerate progress at the intersection of automation and engineering, leading projects that enhance manufacturing efficiency, reduce costs, and drive operational excellence through innovative technol...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Grow your career with a dynamic frontend engineering team focused on building robust platforms. Collaborate across teams to enhance product features, ensure high-quality deliverables, and drive innova...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$132K - $271K *

Drive impactful pre-sales initiatives by delivering tailored product demos, facilitating client workshops, and supporting complex software sales cycles to enhance pipeline conversion and client engage...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$122K - $234K *

Lead the charge in pre-sales support for complex software solutions, delivering impactful demos and tailored proposals. Collaborate with clients and partners to drive pipeline conversion and enhance p...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$88K - $154K *

Optimize and integrate the manufacturing process for hazardous materials, taking ownership from design through commissioning. Collaborate with multidisciplinary teams to ensure safety and efficiency i...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$68K - $119K *

Empower your career by maintaining critical data center infrastructure. You'll ensure optimal performance and reliability of electrical and mechanical systems, contributing to a seamless digital exper...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Elevate client success by managing complex projects, ensuring timely delivery, and maintaining budget integrity. Collaborate with diverse teams to drive engagement and optimize project outcomes from i...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $145K *

Empower your career by enhancing our platform's scalability and reliability. As a Senior Platform Engineer, you'll lead infrastructure improvements, optimize performance, and ensure security while col...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Provide expert technical support and solutions to enhance customer success with Mastercam products, collaborating with teams to optimize workflows and drive product improvements in the West region...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.