Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$88K - $105K *

Advance your career by managing diverse construction projects, ensuring alignment with organizational goals through effective operations and project management, key metrics utilization, and stakeholde...

4 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$86K - $158K *

Lead the design and development of innovative software solutions while ensuring high reliability and performance in a fast-paced environment. Collaborate with cross-functional teams to resolve complex...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$220K - $340K *

Champion construction delivery excellence across global data center sites, managing GC performance and budgets of $25M+. Lead strategy, negotiate contracts, and represent construction risks to executi...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$152K - $223K *

Drive operational transformation and cloud readiness by leading database modernization initiatives, improving reliability and engineering excellence through automation and best practices while mentori...

RemoteRemote

Reposted today

  •   11 - 15 years exp.  •   Telecommunications & Hardware

$110K - $132K *

Engineer and maintain secure, reliable WAN infrastructure for DoD, ensuring connectivity across classified and unclassified networks. Lead modernization efforts and provide expert troubleshooting supp...

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $132K *

Lead the charge in enhancing global WAN infrastructure for a DoD customer, ensuring secure connectivity and modernizing network services. Collaborate with teams to design, implement, and troubleshoot...

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $155K *

Engineer robust data exchange solutions across regions, ensuring compliance and security. Develop scalable backend services and data pipelines while collaborating globally with cross-functional teams...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$86K - $165K *

Join a team that's at the forefront of defense innovation. As a DevOps Software Engineer, you'll drive development and maintenance for advanced defense systems, ensuring secure software delivery and c...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$145K - $170K *

Join a dynamic eCommerce team to enhance the online booking experience. Lead complex features in a Next.js and TypeScript application, impacting conversion and patient trust across multiple countries...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$172K - $240K *

Join a team that's redefining AI security! As a Principal AI Security Engineer, you'll lead assessments, design controls, and partner with teams to ensure safe AI adoption across the enterprise, drivi...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $184K *

Lead the charge in enhancing platform security and infrastructure as a Senior Software Engineer. Utilize your Python expertise and SRE mindset to drive critical improvements, mentor teammates, and ens...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Engage in innovative process design engineering for life sciences projects, leading feasibility studies to construction. Collaborate with clients and mentor junior engineers while ensuring compliance...

2 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$110K - $130K *

Join a team that's dedicated to leading a multidisciplinary engineering department, fostering collaboration, and driving project success while mentoring engineers across various disciplines in a dynam...

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$130K - $155K *

Develop and oversee the governed context layer for AI systems, ensuring robust data architecture and standards. Collaborate with digital workers to enhance data engineering practices and drive innovat...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$60K - $120K *

Unlock potential by deploying and supporting advanced robotic systems in diverse environments. Collaborate with teams, troubleshoot issues, and enhance client experiences through effective communicati...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$250K - $500K+*

Drive innovation by collaborating with hardware teams to enhance tools, evolve compilers, and improve developer experiences, ensuring efficient and effective hardware design processes...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $150K *

Lead the charge in delivering complex integrations for clients, embedding with their teams to build reusable assets against our API. Transform vague requests into actionable plans while enhancing depl...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $155K *

Engineer and enhance security automation for cloud-native applications, integrating AI capabilities to improve vulnerability management and secure development practices across the software development...

2 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$86K - $137K *

Optimize project outcomes as you manage small to medium-sized initiatives. Collaborate across teams, navigate risks, and ensure timely delivery of quality solutions while enhancing communication and s...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Unlock potential by leading technical vision and mentoring engineers. Drive modernization and collaboration across teams to build resilient, scalable infrastructure while fostering a high-performance...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$108K - $162K *

Join a team that's shaping the future of data engineering by developing scalable solutions for network capacity planning and optimization. Collaborate across disciplines to enhance data quality and su...

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$102K - $163K *

Shape the future of respiratory care by leading systems engineering efforts for innovative medical devices. Collaborate cross-functionally to ensure product safety, reliability, and compliance while d...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$101K - $150K *

Optimize project execution by leading Procore administration, training, and compliance. Ensure effective adoption and continuous improvement of workflows, enhancing data quality and operational excell...

3 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$85K - $125K *

Accelerate progress at the forefront of mobile development by leveraging AI tools to enhance iOS applications. Collaborate with cross-functional teams to deliver high-quality, customer-centric marketp...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Transportation

$75K - $110K *

Unlock the potential of your desktop support skills as you become the primary expert in Microsoft Windows administration, providing essential technical support and ensuring seamless operations for our...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.