Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$95K - $115K *

Lead the design and development of innovative VG Systems, enhancing product quality and operational efficiency. Collaborate with cross-functional teams to drive technical improvements and influence st...

4 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$153K - $213K *

Take ownership of a customer-facing product area, driving strategy and execution. Collaborate cross-functionally to enhance user experience, leverage AI, and achieve key performance metrics while deli...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$85K - $117K *

Play a key role in providing advanced technical support for CNC systems, optimizing performance, and collaborating with teams to enhance automation solutions. Engage with customers and partners to res...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Transform complex data systems by designing and implementing scalable solutions that enhance analytics and drive business intelligence in a collaborative, Agile environment focused on healthcare compl...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$145K - $175K *

Transform your career by architecting secure, scalable Azure solutions that drive modern application delivery. Collaborate with diverse teams to develop automation and enhance cloud services while lev...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Champion the development of an autonomous AI platform through full-stack engineering, enhancing multi-agent systems and ensuring robust quality and safety standards across production deployments...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $130K *

Optimize marketing workflows by building AI agents and automated systems. Collaborate with teams to enhance CRM and lifecycle automation, focusing on performance marketing and organic growth through i...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Consumer Technology

$173K - $255K *

Elevate your career by defining and enforcing workload safety standards for a growing EKS fleet. Collaborate across teams to enhance availability and performance while mentoring engineers and driving...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $120K *

Unlock potential by serving as a technical partner to sales, providing expertise in automation solutions. Manage application opportunities, engage with customers, and recommend improvements to align t...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$115K - $275K *

Manage the delivery of GPU clusters for AI workloads by coordinating teams across engineering, networking, and operations. Develop strategies, manage risks, and ensure timely, quality launches to scal...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $125K *

Lead innovative design solutions as a Senior Design Engineer, transforming client needs into actionable broadcast system designs. Collaborate with global teams, mentor junior engineers, and ensure pro...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$214K - $309K *

Unlock potential by leading the design and implementation of advanced identity solutions for AI agents. Collaborate across teams to build scalable frameworks and drive technical excellence in a dynami...

RemoteRemote

Today

  •   11 - 15 years exp.  •   Telecommunications & Hardware

$150K - $180K *

Join a team that's redefining software development leadership by driving strategic initiatives, enhancing team capabilities, and ensuring high-quality delivery across platforms. Lead a talented team t...

3 weeks ago

  •   11 - 15 years exp.  •   Transportation

$112K - $149K *

Drive innovation by building and maintaining data pipelines and governance policies in a hybrid cloud environment. Collaborate with a small team to ensure reliable data flow and access control, enhanc...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$135K - $145K *

Innovate data solutions by building and maintaining robust pipelines that empower critical processes. Collaborate with engineers and stakeholders to enhance data reliability and efficiency in a high-t...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $145K *

Take ownership of automating workflows across teams by building AI agents using Claude and Microsoft Copilot. Collaborate with various departments to identify automation opportunities, ensuring securi...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$178K - $331K *

Transform the future of software products by leading the development and lifecycle management of a cutting-edge SaaS platform, ensuring rapid deployment, customer satisfaction, and continuous enhancem...

3 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$141K - $177K *

Join us to shape the future of cybersecurity by leading product vision and strategy for our innovative Autonomous and Continuous pentesting platform, driving impactful solutions that enhance security...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$100K - $120K *

Drive security excellence by managing identity access, external testing, and compliance processes. Collaborate with teams to enhance AWS security and develop scalable policies, ensuring robust protect...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$86K - $165K *

Transform your career by developing full-stack web applications and modernizing legacy software. Collaborate in a dynamic environment, troubleshoot complex systems, and contribute to innovative soluti...

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$86K - $165K *

Empower innovation by developing full-stack web applications and modernizing legacy systems. Collaborate on troubleshooting, testing, and integration to enhance software performance in a secure enviro...

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$116K - $165K *

Drive engineering excellence by leading the design and integration of marine vessels. Collaborate across teams to ensure compliance and quality in hull structure, propulsion, and auxiliary systems, wh...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$174K - $209K *

Empower our team by driving innovative projects from concept to operation, enhancing the reliability and performance of our observability systems while collaborating in a fully remote environment focu...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$197K - $307K *

Lead the development and optimization of cutting-edge perception algorithms for robotics, enhancing safety and efficiency in dynamic environments while collaborating across teams to ensure cohesive ro...

4 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$146K - $298K *

Lead the charge in shaping data, automation, and AI architecture for a major business segment. Drive strategic initiatives, mentor a high-performing team, and collaborate with stakeholders to enhance...

Yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.