Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$165K - $175K *

Empower engineering teams to enhance assessment services through leadership, technical expertise, and responsible AI adoption. Drive team performance and customer outcomes across diverse product areas...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$125K - $150K *

Lead the design and delivery of scalable banking features, ensuring reliability and security in real-time money movement. Mentor engineers and collaborate with cross-functional teams to create high-qu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$75K - $140K *

Develop, test, and debug software solutions while collaborating with teams to enhance system capabilities. Apply standards and processes throughout the development life cycle to ensure quality and eff...

6 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$79K - $147K *

Drive innovation by collaborating across diverse engineering teams to develop and integrate complex electrical systems. Ensure alignment on design parameters and maintain critical interfaces in a dyna...

2 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$250K - $413K *

Engineer innovative TV app features that enhance user experiences. Collaborate with cross-functional teams to shape the future of entertainment, impacting millions globally through cutting-edge techno...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$180K - $229K *

Join a team that's shaping the future of insurance technology by leading engineering efforts, collaborating with cross-functional teams, and driving strategic initiatives to enhance product effectiven...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$91K - $169K *

Transform software development by designing, testing, and debugging innovative solutions. Collaborate with teams to ensure high standards and effective processes throughout the software lifecycle, add...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$91K - $169K *

Contribute to innovative software development by designing, coding, and testing solutions that address complex business challenges. Collaborate with multidisciplinary teams to ensure high-quality soft...

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$91K - $169K *

Join a dynamic team driving innovative software solutions through the full development life cycle. Utilize your expertise in Python and engage with cutting-edge technologies to solve complex business...

1 month ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$91K - $169K *

Engage in the software development life-cycle, collaborating within an Agile team to create innovative web applications that safeguard space assets, focusing on communication and technical excellence...

1 month ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$120K - $224K *

Lead the charge in developing and integrating full-stack software solutions for command and control applications, enhancing team capabilities and ensuring tool adoption in a collaborative environment...

1 month ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$135K - $160K *

Elevate security practices by building and managing a comprehensive security program. Collaborate with engineers to identify vulnerabilities, implement automated checks, and ensure robust protection a...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$163K - $226K *

Lead the AI enablement initiative, crafting tools and workflows to empower engineers across the organization, enhancing productivity and safety through innovative AI technologies and practices...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $130K *

Drive the design and deployment of secure AI applications in cloud environments, integrating advanced technologies like machine learning and ServiceNow solutions to enhance operational efficiency and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$145K - $185K *

Lead and inspire engineering teams to deliver high-quality digital products, ensuring alignment with business priorities while fostering a culture of collaboration and continuous improvement in a dyna...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$175K - $185K *

Join a team that's dedicated to delivering high-quality backend services, integrating new partners, and enhancing workflows. Leverage your extensive experience to architect solutions that support a dy...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$200K - $275K *

Join a team that's scaling innovative distributed systems across our platform, shaping technical frameworks, and driving organizational growth while collaborating with talented engineers in a dynamic...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Transform the future of AI systems by building robust data pipelines and APIs. Collaborate with Product to refine specifications and enhance user experience, ensuring high-quality delivery and continu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Transform cloud platforms by enhancing capabilities and reducing technical debt. Contribute to full stack development using Python and Go, while building scalable solutions and maintaining cloud infra...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Grow with us as you manage and scale cutting-edge infrastructure, ensuring optimal performance for a rapidly expanding system serving millions of requests daily. Collaborate in a hands-on role where y...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Innovate and drive AI agent development for clinical trial platforms, integrating LLMs through the .NET stack. Engage in hands-on engineering to deliver end-to-end AI features, enhancing patient-centr...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Contribute to the development of innovative AI agents and workflows for clinical trials, integrating backend LLMs with front-end applications while ensuring compliance and reliability in a fast-paced...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$126K - $201K *

Develop cutting-edge machine learning models to enhance perception performance for autonomous driving. Collaborate cross-functionally to tackle complex challenges and drive software solutions from pro...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Join a pioneering team where you'll innovate software solutions for framing and structural analysis. Collaborate closely with cross-functional teams, set technical direction, and contribute to softwar...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$125K - $135K *

Architect a unified operational dashboard connecting diverse alert systems to streamline monitoring and enhance triage efficiency, ensuring critical alerts are prioritized and effectively routed...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.