Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$135K - $160K *

Lead the architecture of certificate lifecycle management capabilities that enhance security across complex environments, collaborating with product and engineering teams to build scalable systems tha...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $100K *

Champion the design and implementation of advanced communication systems, ensuring optimal functionality through troubleshooting and support. Collaborate across teams while managing extensive travel t...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$110K - $130K *

Join a team that's dedicated to transforming healthcare data solutions. As a Senior Data Engineer, you'll enhance complex systems, collaborate across departments, and drive analytics to optimize finan...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$139K - $159K *

Transform data engineering by designing and operating scalable pipelines for enterprise data lakes, ensuring data integrity and accessibility while collaborating with a dynamic team dedicated to clien...

3 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$169K - $220K *

Join a team that's dedicated to transforming healthcare through innovative software solutions. Collaborate with engineers and healthcare professionals to build systems that enhance patient care and st...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Optimize energy solutions by leading technical projects, conducting site surveys, and collaborating with teams to deliver innovative, cost-effective strategies that enhance facility performance and su...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$100K - $120K *

Drive innovation in digital experiences by building and optimizing high-performing web applications. Collaborate with creative teams to enhance customer engagement across platforms while managing the...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Elevate your career by developing robust embedded firmware for safety-critical systems. Collaborate on real-time architectures and integrate with Embedded Linux, ensuring reliability and compliance in...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$150K - $300K *

Transform enterprise operations by developing AI solutions tailored to customer needs. Engage directly with clients, manage the full technical lifecycle, and drive measurable improvements in AI perfor...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$130K - $155K *

Join a team that's dedicated to building innovative marketplace solutions. As a Senior Software Engineer, you'll collaborate with cross-functional teams to deliver high-quality software, enhancing fle...

RemoteRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$180K - $220K *

Deliver innovative data pipelines for legal records, transforming unstructured data into actionable insights while supporting advanced AI workflows and data quality improvements for robust legal resea...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Staffing

$172K - $215K *

Advance your career by leading software development initiatives, driving architecture design, and optimizing performance in a collaborative environment. Engage with cross-functional teams to deliver s...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Enterprise Technology

$123K - $254K *

Architect innovative full-stack solutions that enhance user experiences, collaborating with cross-functional teams to drive product development from ideation to release, while ensuring high-quality co...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$120K - $145K *

Shape the future of AI by developing advanced software solutions for autonomous agents and multi-agent systems. Engage in the full development lifecycle while collaborating in an Agile environment to...

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$130K - $180K *

Build a robust data foundation to elevate Market Intelligence. Drive automation and streamline data workflows, enriching insights for research and publishing, while ensuring data integrity and accessi...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Partner with us to design and implement engaging front-end experiences for leading eCommerce brands. Leverage your skills in Figma and Shopify to create custom loyalty solutions, collaborating closely...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Pioneer secure cloud solutions by leveraging your DevSecOps expertise to enhance computing architecture and brokerage services, ensuring compliance with DoD frameworks while mentoring teams and drivin...

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$158K - $198K *

Transform enterprise storage management by leading a specialized team in z/OS environments. Oversee IBM storage systems, ensuring security, performance, and availability while collaborating closely wi...

3 weeks ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$82K - $172K *

Drive innovation as a Senior AI/ML Engineer, tackling complex challenges in AI/ML algorithm development across diverse domains, while collaborating with interdisciplinary teams to enhance cutting-edge...

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Join us to enhance the security posture of our production platform. As an Infrastructure Security Engineer, you'll drive remediation efforts, build security frameworks, and collaborate with teams to p...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$198K - $297K *

Join us to lead the design and evolution of a cutting-edge Real-Time Analytics Platform, driving high-throughput, low-latency data solutions. Collaborate with cross-functional teams to enhance scalabi...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$82K - $172K *

Drive the direction and clarity of complex software systems, ensuring seamless operational integration while collaborating with diverse teams to meet critical requirements and enhance mission success...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Lead the charge in transforming healthcare technology by architecting innovative solutions that enhance patient access and care. Collaborate with industry leaders to tackle high-stakes challenges and...

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$166K - $230K *

Empower your career as a Senior Infrastructure Engineer focusing on enhancing Lakehouse infrastructure, security, and cost efficiency while collaborating with cross-functional teams to optimize data p...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Finance & Insurance

$135K - $160K *

Transform data solutions by architecting enterprise-grade pipelines, leading a high-performing team, and embedding best practices to create scalable, robust data environments for analysis and insights...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.