Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and technology roles to positions in finance, healthcare, engineering, and operations. Whether you’re considering a move to a major city or looking for opportunities closer to home, explore roles that match your experience and career goals.

Where to Find High-Paying Jobs in Ohio

Ohio’s job market spans major metropolitan areas and growing regional economies. Explore opportunities in Columbus, Cleveland, Cincinnati, and other communities throughout the state. Employers across industries seek experienced professionals for roles in corporate leadership, technology, healthcare, manufacturing, financial services, and more. Available positions and compensation vary by employer, location, and qualifications.

Industries and Career Paths

Ohio offers career possibilities across established and emerging sectors. Depending on your background, you may find senior-level opportunities in business management, software and information technology, healthcare administration, engineering, supply chain, sales, and finance. Use Ladders to search current listings and identify roles suited to your skills and professional experience.

Find the Right Ohio Opportunity

Make your search more focused by filtering listings by location, job title, industry, and other preferences. Review each posting for its responsibilities, requirements, and compensation details, then tailor your application to highlight relevant accomplishments. New opportunities are added over time, so check back regularly for the latest $100K+ jobs in Ohio.

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$110K - $130K *

Transform cloud platforms by enhancing capabilities and reducing technical debt. Contribute to full stack development using Python and Go, while building scalable solutions and maintaining cloud infra...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Grow with us as you manage and scale cutting-edge infrastructure, ensuring optimal performance for a rapidly expanding system serving millions of requests daily. Collaborate in a hands-on role where y...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Innovate and drive AI agent development for clinical trial platforms, integrating LLMs through the .NET stack. Engage in hands-on engineering to deliver end-to-end AI features, enhancing patient-centr...

US-AnywhereRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Help us shape innovative solutions by applying your software expertise and problem-solving skills. Your role is crucial in developing high-quality applications in a collaborative, agile environment, a...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Join a pioneering team where you'll innovate software solutions for framing and structural analysis. Collaborate closely with cross-functional teams, set technical direction, and contribute to softwar...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$125K - $135K *

Architect a unified operational dashboard connecting diverse alert systems to streamline monitoring and enhance triage efficiency, ensuring critical alerts are prioritized and effectively routed...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Lead the charge in driving innovative solutions and strategies that enhance operational efficiency and customer satisfaction across diverse teams and projects. Collaborate with stakeholders to achieve...

US-AnywhereRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$87K - $135K *

Drive your career forward by leading systems engineering for a cloud-based enterprise system. Engage in architecture development, integration, and modernization efforts while ensuring security and ope...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $195K *

Lead the charge in building scalable, high-performance software solutions. Collaborate with cross-functional teams to implement integrations, optimize performance, and mentor junior developers in a fa...

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Create real-time user interface applications for automated aircraft systems, collaborating with a dynamic team of engineers. Lead the design and implementation to enhance pilot experiences, ensuring s...

US-AnywhereRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$110K - $130K *

Elevate your career by designing and maintaining advanced IT infrastructure platforms, ensuring reliability and security. Collaborate with teams to optimize solutions, automate processes, and enhance...

US-AnywhereRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$108K - $130K *

Partner with us to innovate and deliver high-impact retail solutions. Drive end-to-end execution as a key technical leader, engaging clients while mentoring teams and ensuring top-notch operational de...

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Take ownership of the technical strategy for a pioneering AI-native platform, making critical engineering decisions that influence the organization's future while mentoring a team to elevate overall t...

US-AnywhereRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $148K *

Join a team that's shaping the future of AEC software by leading engineering talent and enhancing workflows. Drive innovation in Autodesk Revit add-ins and tools while fostering a collaborative enviro...

US-AnywhereRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$139K - $174K *

Join our team to shape the future of our platform by designing robust APIs, improving service connectivity, and evolving legacy systems into modern architectures, all while fostering a collaborative e...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$180K - $240K *

Transform the future of distributed systems by designing and building robust platform components. Collaborate with teams to ensure reliability and scalability in mission-critical environments, driving...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$90K - $110K *

Champion the development of advanced data management tools, collaborating with a skilled team to enhance mission capabilities at a leading intelligence center. Engage in diverse full-stack engineering...

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $135K *

Take ownership of features from design to production, enhance system reliability, and collaborate closely with engineers, product, and design teams to solve complex technical challenges in a dynamic e...

US-AnywhereRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $200K *

Transform backend services and REST APIs in a collaborative environment. Leverage your software engineering skills to support cyber training initiatives, utilizing modern technologies and cloud infras...

US-AnywhereRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $170K *

Develop and enhance Python services for pharmacy claims processing. Collaborate across teams to deliver high-quality solutions while gaining expertise in the pharmacy benefits domain. Embrace a hybrid...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Unlock potential by driving innovative, AI-powered financial audit solutions. Collaborate with cross-functional teams to design agent-driven experiences and own complex onboarding workflows for major...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$154K - $260K *

Develop AI-driven workflows to enhance CI/CD systems, ensuring safe, efficient software delivery. Collaborate with teams to reduce tech debt and improve production reliability while scaling engineerin...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$103K - $155K *

Join the charge in transforming data, analytics, and AI by ensuring the reliability and security of critical data pipelines. Collaborate with cross-functional teams to enhance operational excellence a...

US-AnywhereRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$175K - $225K *

Optimize Shopify's checkout and post-purchase experiences by developing key features and tools. Collaborate with a small, autonomous team, tackling challenges across multiple systems with a focus on p...

US-AnywhereRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$130K - $200K *

Join our team to shape the future of construction tech by building impactful tools for professionals. Leverage your expertise to create user-focused solutions that enhance productivity, reliability, a...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Listings may include professional and senior-level roles in fields such as technology, healthcare, finance, engineering, manufacturing, sales, and business operations. Job availability depends on current employer postings.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Explore listings in Columbus, Cleveland, Cincinnati, and other Ohio cities and communities. Use location filters to find opportunities in the areas that work for you.

  • How can I search for jobs in Ohio on Ladders?question toggle

    Browse Ohio job listings and narrow your results by location, job title, industry, or other available filters. Check each posting for salary information, qualifications, and application instructions.

  • Are Ohio jobs on Ladders guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, since pay and eligibility requirements vary by role and employer.