Explore $100K+ Jobs in Kentucky

Discover high-paying professional opportunities across Kentucky with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re interested in positions in Louisville, Lexington, Bowling Green, or elsewhere in the state, find opportunities that fit your experience and career goals.

Professional Opportunities Across Kentucky

Kentucky’s economy spans healthcare, manufacturing, logistics, finance, technology, education, and other industries. Employers across the state seek experienced professionals for roles in leadership, operations, engineering, sales, healthcare administration, and more. The right opportunity may be available in a major metro area or in a smaller community.

Find a Role That Fits Your Experience

Use Ladders to explore opportunities suited to your skills, seniority, and compensation expectations. Review job descriptions, compare responsibilities, and identify roles where your professional background can make an impact. Listings on Ladders are vetted and pay at least $100,000.

Advance Your Career in Kentucky

Build your next career move by searching Kentucky jobs and narrowing results by location, industry, and role. Check listings regularly, tailor your resume to each opportunity, and highlight measurable accomplishments that demonstrate your value to prospective employers.

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$110K - $130K *

Innovate and drive AI agent development for clinical trial platforms, integrating LLMs through the .NET stack. Engage in hands-on engineering to deliver end-to-end AI features, enhancing patient-centr...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Help us shape innovative solutions by applying your software expertise and problem-solving skills. Your role is crucial in developing high-quality applications in a collaborative, agile environment, a...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Join a pioneering team where you'll innovate software solutions for framing and structural analysis. Collaborate closely with cross-functional teams, set technical direction, and contribute to softwar...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$125K - $135K *

Architect a unified operational dashboard connecting diverse alert systems to streamline monitoring and enhance triage efficiency, ensuring critical alerts are prioritized and effectively routed...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Lead the charge in driving innovative solutions and strategies that enhance operational efficiency and customer satisfaction across diverse teams and projects. Collaborate with stakeholders to achieve...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$87K - $135K *

Drive your career forward by leading systems engineering for a cloud-based enterprise system. Engage in architecture development, integration, and modernization efforts while ensuring security and ope...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $155K *

Grow your career with a dynamic team focused on designing and implementing scalable systems. Collaborate on complex projects, mentor peers, and drive technical excellence while contributing to impactf...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $145K *

Create real-time user interface applications for automated aircraft systems, collaborating with a dynamic team of engineers. Lead the design and implementation to enhance pilot experiences, ensuring s...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$110K - $130K *

Elevate your career by designing and maintaining advanced IT infrastructure platforms, ensuring reliability and security. Collaborate with teams to optimize solutions, automate processes, and enhance...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Drive the modernization of online platforms by leveraging .NET technologies. Collaborate with cross-functional teams to enhance consumer-facing websites, ensuring optimal user experience through agile...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Take ownership of the technical strategy for a pioneering AI-native platform, making critical engineering decisions that influence the organization's future while mentoring a team to elevate overall t...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $148K *

Join a team that's shaping the future of AEC software by leading engineering talent and enhancing workflows. Drive innovation in Autodesk Revit add-ins and tools while fostering a collaborative enviro...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$135K - $180K *

Drive innovative electrical design solutions for high-density compute environments. Collaborate across teams to ensure compliance with industry standards while mentoring junior engineers. Make a signi...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$139K - $174K *

Join our team to shape the future of our platform by designing robust APIs, improving service connectivity, and evolving legacy systems into modern architectures, all while fostering a collaborative e...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$180K - $240K *

Transform the future of distributed systems by designing and building robust platform components. Collaborate with teams to ensure reliability and scalability in mission-critical environments, driving...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$101K - $206K *

Innovate with a team that's transforming healthcare through AI-driven software. Lead the development of scalable solutions, mentor engineers, and enhance workflows in a dynamic environment that impact...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$162K - $186K *

Build and enhance backend services for a global insurance platform, collaborating with cross-functional teams to deliver scalable solutions and improve user experience through data-driven insights and...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Hospitality & Recreation

$125K - $135K *

Take ownership of features from design to production, enhance system reliability, and collaborate closely with engineers, product, and design teams to solve complex technical challenges in a dynamic e...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $200K *

Transform backend services and REST APIs in a collaborative environment. Leverage your software engineering skills to support cyber training initiatives, utilizing modern technologies and cloud infras...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $170K *

Develop and enhance Python services for pharmacy claims processing. Collaborate across teams to deliver high-quality solutions while gaining expertise in the pharmacy benefits domain. Embrace a hybrid...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Unlock potential by driving innovative, AI-powered financial audit solutions. Collaborate with cross-functional teams to design agent-driven experiences and own complex onboarding workflows for major...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$154K - $260K *

Develop AI-driven workflows to enhance CI/CD systems, ensuring safe, efficient software delivery. Collaborate with teams to reduce tech debt and improve production reliability while scaling engineerin...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Optimize security infrastructure by building workload identity systems that streamline authentication and authorization, enhancing developer experience while bolstering compliance across applications...

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$175K - $225K *

Optimize Shopify's checkout and post-purchase experiences by developing key features and tools. Collaborate with a small, autonomous team, tackling challenges across multiple systems with a focus on p...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$130K - $200K *

Join our team to shape the future of construction tech by building impactful tools for professionals. Leverage your expertise to create user-focused solutions that enhance productivity, reliability, a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Kentucky?question toggle

    Kentucky listings may include senior and experienced roles in areas such as healthcare, manufacturing, logistics, finance, technology, sales, engineering, and operations. Available positions vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Opportunities may be found in Louisville, Lexington, Bowling Green, and communities throughout the state. Search by location to explore current openings near you.

  • Do jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with advertised salaries of $100,000 or more. Review each listing for its specific compensation details and requirements.

  • How can I find a high-paying job in Kentucky?question toggle

    Search Kentucky listings by city, role, or industry, then review the qualifications and compensation details. Tailor your resume to the position and emphasize relevant accomplishments and leadership experience.