Welcome to our category for Senior Principal Systems Engineer roles. You'll find a range of opportunities spanning from systems development to technical leadership.
As a Senior Principal Systems Engineer, you'll oversee system architecture, guide technical teams, and address the most complex engineering challenges.
Ladders values your high-level analytical, design and leadership skills. Join us, expand your career opportunities and land the job you're aiming for.
Senior Project Manager, Oncology
$122K *
Champion project success by leading the global team in Oncology, ensuring adherence to budgets, timelines, and quality standards while fostering client relationships and supporting business developmen...
Reposted 1 week ago
Substation Civil Structural Engineer
$59K - $106K *
Advance high voltage utility projects by designing and leading substation civil and structural components. Collaborate with a diverse team to deliver impactful engineering solutions while maintaining...
1 month ago
Technical Leader II - Nuclear Risk Assessment and Applications
$138K - $150K *
Grow your career with a dynamic role focusing on probabilistic risk assessment in the nuclear sector. Contribute to innovative research projects and engage with diverse stakeholders to enhance safety...
3 weeks ago
Senior Practice Engagement Manager
$120K - $150K *
Accelerate business transformation by leading Sourcing and Procurement initiatives. Collaborate with diverse teams to drive proposals, enhance client relationships, and provide strategic insights to o...
Reposted 1 week ago
Senior Manager, Process Performance and Quality Control (Remote)
$132K - $251K *
Lead the Process Performance and Quality Control team to enhance global trade compliance, developing metrics and audit processes to mitigate risk and improve efficiency across key compliance functions...
Reposted 5 days ago
Director of Solutions Architecture
$130K - $180K *
Shape innovative technical solutions in a dynamic environment. Lead enterprise architecture efforts to enhance network engineering and cybersecurity, collaborating with stakeholders for business growt...
4 days ago
Senior Customer Advocacy Manager
$155K - $170K *
Engage customers as advocates by leading impactful storytelling programs that drive business growth and showcase success narratives. Collaborate across teams to amplify the voices of thought leaders a...
4 days ago
Senior Software Engineer, Platform
$160K - $170K *
Innovate scalable backend services and optimize performance by leading cross-functional teams in a dynamic environment. Champion engineering excellence and develop cohesive REST APIs while ensuring hi...
2 weeks ago
$100K - $130K *
Optimize project management efforts for engineering initiatives across all domestic sites, overseeing the full lifecycle from planning through execution, while ensuring compliance with industry regula...
Reposted 2 days ago
Senior Cloud Cybersecurity Engineer
$154K - $236K *
Drive security excellence in cloud environments by enhancing detection and response capabilities using modern engineering practices and DevOps methodologies, while collaborating cross-functionally to...
1 week ago
Software Engineer, Data Platform
$170K - $220K *
Grow your career with us by building scalable, reliable data systems that power our products. As a Software Engineer, you'll enhance our identity data platform and ensure its integrity and efficiency...
1 week ago
$144K - $165K *
Drive the strategic design and implementation of cutting-edge enterprise data platforms, managing integration and modernization efforts. Collaborate with multiple systems and lead innovative solutions...
2 weeks ago
Senior Cloud Engineer, Cloud Platform
$100K - $130K *
Drive the advancement of cloud platform capabilities and enhance user experiences by leading architectural improvements, mentoring teams, and embracing a DevOps culture to automate and secure deployme...
1 week ago
Control System Designer, Data Centers - Remote (U.S.)
$90K - $130K *
Elevate your career by designing cutting-edge automation and SCADA systems for global data center projects. Collaborate with multidisciplinary teams to drive innovation in mission-critical infrastruct...
4 days ago
Senior Clinical Research Associate
$90K - $120K *
Oversee the monitoring and management of clinical study sites, ensuring compliance with international guidelines and local regulations while promoting effective communication and collaboration among s...
2 days ago
$120K - $150K *
Elevate the developer experience by building and owning vital platform tooling, improving observability, and enhancing deployment processes to empower engineers with seamless infrastructure access and...
1 week ago
Sr. Manager, SAP DT Lead - Business Transformation (REMOTE)
$132K - $251K *
Unlock potential by leading transformative SAP initiatives for mergers and acquisitions, ensuring seamless financial migrations and compliance with regulatory standards in a dynamic environment...
6 days ago
Director of Product Engineering
$130K - $180K *
Shape the future of product engineering by leading talented teams, setting delivery expectations, and fostering a culture of quality. Drive alignment between engineering, product, and architecture whi...
2 weeks ago
$90K - $130K *
Lead and manage complex cybersecurity programs, driving innovation and operational excellence while coordinating multi-location contractor teams and aligning projects with NIAID goals...
Reposted 4 days ago
$120K - $150K *
Help us design and deliver innovative enterprise solutions that modernize legacy healthcare systems, enhance interoperability, and drive digital transformation initiatives supporting Veteran healthcar...
2 weeks ago
$90K - $130K *
Reimagine program management in a dynamic role overseeing complex projects and teams, driving financial and contract management, while ensuring the delivery of innovative health IT solutions and effec...
Reposted 4 days ago
$100K - $130K *
Transform scientific computing support by leading program management efforts, ensuring financial integrity and operational excellence while collaborating with key stakeholders to enhance mission objec...
Reposted 4 days ago
$187K - $234K *
Lead, coach, and develop a high-performing team to enhance platform capabilities, driving accountability and owner-ship in delivering reliable and effective engineering solutions across the organizati...
2 weeks ago
Program Manager - Remote (Mgr Programs 2) - 29055
$145K - $210K *
Join a team that's dedicated to enhancing military capabilities through innovative software development. Lead the Minotaur Mission Processor project by driving strategies, managing resources, and ensu...
6 days ago
Senior Product Manager, AI Platform and Developer Productivity
$208K - $327K *
Shape the future of AI platforms by defining product vision and leading initiatives that enhance developer experiences across large-scale systems, driving clarity and alignment within a dynamic cross...
4 weeks ago
What does a Senior Principal Systems Engineer do?
A Senior Principal Systems Engineer handles system architecture, leads technical teams, and solves advanced engineering problems. They're often responsible for guiding overall system design and integration.
What skills do I need to have for these roles?
Skills commonly required include system design, team leadership, analytical thinking and knowledge in systems integration.
What industries hire Senior Principal Systems Engineers?
Industries like Technology, Aerospace, Defense, Telecommunications, and more require the expertise of Senior Principal Systems Engineers.