Discover Senior Principal Systems Engineer Jobs

Welcome to our category for Senior Principal Systems Engineer roles. You'll find a range of opportunities spanning from systems development to technical leadership.

Senior Principal Systems Engineer Roles

As a Senior Principal Systems Engineer, you'll oversee system architecture, guide technical teams, and address the most complex engineering challenges.

Where Your Skills are Valued

Ladders values your high-level analytical, design and leadership skills. Join us, expand your career opportunities and land the job you're aiming for.

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$150K - $250K *

Innovate the next generation of high-performance Lustre capabilities, collaborating with senior engineers to optimize storage infrastructure through hands-on development, feature design, and scalabili...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$70K - $95K *

Elevate your career by deploying and troubleshooting network solutions while enhancing security protocols. Collaborate with a dedicated team to improve our services and support a diverse array of cust...

US-AnywhereRemote

4 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$157K - $174K *

Join us to design and implement enterprise knowledge architecture, ensuring cross-domain consistency and governance for metadata standards. Your expertise will enable data interoperability and support...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$157K - $174K *

Empower enterprise knowledge architecture through effective data modeling and cross-domain consistency. Develop tagging standards, business glossary governance, and knowledge repository architecture t...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$120K - $150K *

Unlock your potential as you design and operate a scalable demo platform that enhances customer engagement for evaluations and internal enablement. Collaborate with teams to automate and standardize d...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$118K - $177K *

Join a team that shapes the future of quality management by leading global tracking and resolution of customer defects, ensuring compliance with regulatory standards while driving cross-functional col...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$131K - $198K *

Shape the future of supply chain technology by driving product vision, strategy, and execution. Collaborate across teams to deliver innovative solutions that transform operations and achieve measurabl...

US-AnywhereRemote

4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $150K *

Pioneer precision and accountability in project scheduling across diverse warehouse builds and automation deployments. Shape the future through effective project coordination and executive reporting t...

US-AnywhereRemote

1 week ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$100K - $130K *

Transform enterprise-scale initiatives by leading impactful programs, engaging with executive stakeholders, and ensuring project delivery excellence. Drive strategic planning and execution to achieve...

US-AnywhereRemote

5 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$140K - $228K *

Elevate your career as a Senior Backend Engineer, driving the development of scalable marketplace experiences and backend systems while collaborating across teams to deliver high-impact solutions and...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $130K *

Lead the charge in implementing and optimizing HCM security and integrations, ensuring effective data migration and configuration while collaborating closely with teams to achieve successful project o...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$94K - $132K *

Shape the future of our product strategy by delivering data-driven insights, collaborating cross-functionally, and influencing executive decisions to drive growth, retention, and profitability across...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$118K - $180K *

Unlock potential by leading comprehensive nuclear project planning efforts that enhance workforce efficiency and safety. Collaborate seamlessly with cross-functional teams to ensure timely delivery of...

US-AnywhereRemote

4 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$145K - $199K *

Transform advanced HPC and GenAI solutions through hands-on deployment, configuration, and benchmarking of GPU systems, collaborating with teams and customers across the U.S. to deliver high-performan...

US-AnywhereRemote

5 days ago

  •   5 - 7 years exp.  •   Technical Services

$152K - $229K *

Unlock your potential by developing real-time simulation software for advanced aircraft systems, engaging with a dynamic team to create high-fidelity models, and leveraging cutting-edge technologies t...

US-AnywhereRemote

4 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$100K - $130K *

Shape the future of critical drug validation by designing, executing, and leading projects that ensure compliance and efficiency across all stages of sterile process qualifications in pharmaceutical m...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$123K - $201K *

Elevate our software engineering capabilities by leading complex system designs and implementations. Collaborate across teams to develop scalable solutions that directly impact mission outcomes, while...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $130K *

Collaborate in a dynamic team to develop innovative mechanical systems for nuclear projects. Leverage your expertise in design, regulatory compliance, and project management to support cutting-edge re...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$220K - $400K *

Transform the future of data activation by leading engineering initiatives in a no-code environment. Shape product development, enhance team performance, and drive recruitment while tackling innovativ...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $140K *

Manage and coordinate project teams in clinical trials, ensuring adherence to budgets and timelines while supporting effective communication between stakeholders to achieve project milestones and enha...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$111K - $150K *

Lead multi-disciplinary survey projects, mentor teams, and drive business development initiatives. Maintain project quality and client satisfaction while managing resources and ensuring compliance wit...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$146K - $195K *

Contribute to the development of AI-driven airspace design software, improving flight path workflows by translating user needs into a cohesive product strategy. Collaborate across teams to enhance saf...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$120K - $150K *

Transform your career by leading complex high-voltage protection and control projects, mentoring engineers, and driving technical governance across utilities. Collaborate on innovative solutions that...

US-AnywhereRemote

Today

  •   15+ years exp.  •   Energy & Utilities

$120K - $150K *

Contribute to high voltage substation projects by providing technical governance, mentoring engineers, and solving complex protection and control challenges from design to completion...

US-AnywhereRemote

Today

  •   15+ years exp.  •   Energy & Utilities

$144K - $155K *

Champion operational excellence by leading a dynamic team focused on quality governance, process improvement, and stakeholder engagement, ensuring KPIs are not just met but exceeded through discipline...

US-AnywhereRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What does a Senior Principal Systems Engineer do?question toggle

    A Senior Principal Systems Engineer handles system architecture, leads technical teams, and solves advanced engineering problems. They're often responsible for guiding overall system design and integration.

  • What skills do I need to have for these roles?question toggle

    Skills commonly required include system design, team leadership, analytical thinking and knowledge in systems integration.

  • What industries hire Senior Principal Systems Engineers?question toggle

    Industries like Technology, Aerospace, Defense, Telecommunications, and more require the expertise of Senior Principal Systems Engineers.