Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Senior Counsel Jobs in Missouri

Sort By: Relevance

$125K - $185K *

Transform strategic sourcing for HR and Benefits, leading complex engagements and driving cost savings while ensuring high supplier performance and stakeholder satisfaction across diverse client needs...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$135K - $155K *

Join a team that's shaping the future of cultural resources management. As a Senior Project Manager, you'll lead initiatives, mentor staff, and collaborate with experts to enhance our services across...

United StatesRemote

Yesterday

  •   15+ years exp.  •   Real Estate & Construction

$115K - $136K *

Innovate by driving new business opportunities with executive finance leaders. Leverage your consultative sales skills to deliver transformative SaaS solutions, ensuring measurable outcomes and buildi...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$190K - $381K *

Empower global partnerships by leading strategy and execution across markets, enhancing relationships with key partners, and driving innovation in financial services. Build a high-performing team to s...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$115K *

Lead a dynamic team to enhance donor engagement and drive fundraising strategies. Oversee major gift initiatives while fostering a culture of mentorship and accountability. Collaborate with leadership...

Today

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$115K *

Lead the charge in cultivating a donor-centered culture while managing a high-performing team. Drive strategic fundraising initiatives and engage with key stakeholders to secure major gifts and enhanc...

6 days ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$87K - $157K *

Lead the execution of the Medicare Compliance Advisory program, ensuring adherence to CMS regulations. Collaborate with stakeholders to provide regulatory guidance, conduct audits, and enhance complia...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$105K - $150K *

Champion integrated marketing campaigns that drive pipeline growth in the Business & Government sector. Collaborate across teams to execute strategies, optimize performance, and leverage AI for innova...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$136K - $215K *

Lead the charge in enhancing enterprise customer relationships by managing renewals, identifying risks, and driving engagement strategies. Collaborate across teams to ensure customer value and satisfa...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $140K *

Lead client service excellence and operational performance across portfolios, driving team development and strategic execution. Collaborate cross-functionally to enhance client experiences and ensure...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$130K - $155K *

Drive creative excellence as a key leader, managing cross-functional teams to deliver innovative solutions and strategic insights while nurturing client relationships and maintaining high creative sta...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$86K - $138K *

Empower your career by leading business analysis efforts, collaborating with stakeholders to enhance system applications, and driving innovative solutions that improve operational efficiency and user...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Empower a vibrant residential life program by providing strategic leadership, overseeing student conduct processes, and fostering an inclusive environment that promotes student success and well-being...

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$180K - $270K *

Transform regulatory compliance in North America by developing strategies and programs that ensure adherence to financial regulations. Collaborate across teams to implement innovative compliance solut...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Accelerate your career by leading a dynamic sales team to drive IT security solutions. Collaborate with clients and partners to enhance sales strategies, mentor talent, and achieve regional objectives...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Transform regulatory environments by configuring and supporting Veeva Vault RIM systems. Collaborate with clients to ensure compliance and reliability while implementing ongoing managed services and a...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$106K - $160K *

Lead complex contract negotiations and drive strategic supplier relationships. Collaborate with stakeholders to assess risks, develop negotiation strategies, and enhance contracting practices while me...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$250K - $300K *

Champion strategic growth by leading the charge to secure complex health system accounts. Drive transformative deals with hands-on coaching, leveraging deep relationships and expertise to elevate team...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$175K - $210K *

Unlock potential by leading strategic business development initiatives that connect biopharmaceutical executives with tailored commercial solutions. Drive growth through relationship-building and inno...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$108K - $200K *

Drive impactful risk and return analysis for property lines, enhancing pricing strategies and capital management. Collaborate with actuarial teams to develop standards and support forecasting efforts...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$81K - $139K *

Optimize your career by joining a dynamic Legal Team, supporting complex contracting and intellectual property matters while safeguarding proprietary technology in a fast-paced environment...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$167K - $300K *

Lead the charge in oncology marketing by developing KOL engagement strategies and insights for individualized therapies. Collaborate cross-functionally to drive brand strategy and launch planning, ens...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$105K - $150K *

Inspire impactful change by leading complex federal digital services programs. Oversee strategy, execution, and customer relationships while managing multidisciplinary teams to deliver high-quality te...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$112K - $225K *

Champion the future of risk management by leveraging your actuarial expertise in a remote role focused on regulatory consulting, pricing, reserving, and reinsurance strategies, while advancing your pr...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $186K *

Join a team that's dedicated to building strong client relationships while leading strategic initiatives in the retirement industry. Leverage your expertise to educate clients, resolve issues, and dri...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.