Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
1557- Director, Strategic Sourcing- Corporate Services
$125K - $185K *
Transform strategic sourcing for HR and Benefits, leading complex engagements and driving cost savings while ensuring high supplier performance and stakeholder satisfaction across diverse client needs...
2 weeks ago
Cultural Resources/Architectural Historian and Senior Project Manager
$135K - $155K *
Join a team that's shaping the future of cultural resources management. As a Senior Project Manager, you'll lead initiatives, mentor staff, and collaborate with experts to enhance our services across...
Yesterday
$115K - $136K *
Innovate by driving new business opportunities with executive finance leaders. Leverage your consultative sales skills to deliver transformative SaaS solutions, ensuring measurable outcomes and buildi...
3 weeks ago
VP - Global Strategic Partnerships
$190K - $381K *
Empower global partnerships by leading strategy and execution across markets, enhancing relationships with key partners, and driving innovation in financial services. Build a high-performing team to s...
3 weeks ago
Associate Vice President of Philanthropy
$115K *
Lead a dynamic team to enhance donor engagement and drive fundraising strategies. Oversee major gift initiatives while fostering a culture of mentorship and accountability. Collaborate with leadership...
Today
Associate Vice President of Philanthropy
$115K *
Lead the charge in cultivating a donor-centered culture while managing a high-performing team. Drive strategic fundraising initiatives and engage with key stakeholders to secure major gifts and enhanc...
6 days ago
Senior Compliance Administrator - Enrollment, Billing, Finance, DIR
$87K - $157K *
Lead the execution of the Medicare Compliance Advisory program, ensuring adherence to CMS regulations. Collaborate with stakeholders to provide regulatory guidance, conduct audits, and enhance complia...
Reposted 1 week ago
Senior Growth Marketing Manager - Business & Government
$105K - $150K *
Champion integrated marketing campaigns that drive pipeline growth in the Business & Government sector. Collaborate across teams to execute strategies, optimize performance, and leverage AI for innova...
1 week ago
Senior Customer Success Manager, Enterprise
$136K - $215K *
Lead the charge in enhancing enterprise customer relationships by managing renewals, identifying risks, and driving engagement strategies. Collaborate across teams to ensure customer value and satisfa...
3 weeks ago
AVP of Client Services (Remote)
$90K - $140K *
Lead client service excellence and operational performance across portfolios, driving team development and strategic execution. Collaborate cross-functionally to enhance client experiences and ensure...
3 weeks ago
Associate Creative Director, Copy
$130K - $155K *
Drive creative excellence as a key leader, managing cross-functional teams to deliver innovative solutions and strategic insights while nurturing client relationships and maintaining high creative sta...
3 weeks ago
Internal Business Systems Consultant
$86K - $138K *
Empower your career by leading business analysis efforts, collaborating with stakeholders to enhance system applications, and driving innovative solutions that improve operational efficiency and user...
Today
Senior Director of Residential Life and Conduct
$80K - $95K *
Empower a vibrant residential life program by providing strategic leadership, overseeing student conduct processes, and fostering an inclusive environment that promotes student success and well-being...
3 weeks ago
US Chief Compliance Officer - Remote
$180K - $270K *
Transform regulatory compliance in North America by developing strategies and programs that ensure adherence to financial regulations. Collaborate across teams to implement innovative compliance solut...
3 weeks ago
$150K - $180K *
Accelerate your career by leading a dynamic sales team to drive IT security solutions. Collaborate with clients and partners to enhance sales strategies, mentor talent, and achieve regional objectives...
4 weeks ago
Regulatory RIM Business Analyst & Managed Services Consultant
$100K - $120K *
Transform regulatory environments by configuring and supporting Veeva Vault RIM systems. Collaborate with clients to ensure compliance and reliability while implementing ongoing managed services and a...
1 week ago
Sr. Principal Contract Negotiation Analyst
$106K - $160K *
Lead complex contract negotiations and drive strategic supplier relationships. Collaborate with stakeholders to assess risks, develop negotiation strategies, and enhance contracting practices while me...
1 week ago
Head of National Strategic Accounts
$250K - $300K *
Champion strategic growth by leading the charge to secure complex health system accounts. Drive transformative deals with hands-on coaching, leveraging deep relationships and expertise to elevate team...
Reposted 2 weeks ago
Director/Senior Director Commercial Business Development
$175K - $210K *
Unlock potential by leading strategic business development initiatives that connect biopharmaceutical executives with tailored commercial solutions. Drive growth through relationship-building and inno...
1 week ago
Actuarial Consultant - P&C Property Risk and Actuarial
$108K - $200K *
Drive impactful risk and return analysis for property lines, enhancing pricing strategies and capital management. Collaborate with actuarial teams to develop standards and support forecasting efforts...
Yesterday
Intellectual Property & Contracts Paralegal
$81K - $139K *
Optimize your career by joining a dynamic Legal Team, supporting complex contracting and intellectual property matters while safeguarding proprietary technology in a fast-paced environment...
1 week ago
Thought Leader Liaison, US Oncology, West
$167K - $300K *
Lead the charge in oncology marketing by developing KOL engagement strategies and insights for individualized therapies. Collaborate cross-functionally to drive brand strategy and launch planning, ens...
1 week ago
Program Manager - Federal Financial / Regulatory Service
$105K - $150K *
Inspire impactful change by leading complex federal digital services programs. Oversee strategy, execution, and customer relationships while managing multidisciplinary teams to deliver high-quality te...
Reposted 6 days ago
$112K - $225K *
Champion the future of risk management by leveraging your actuarial expertise in a remote role focused on regulatory consulting, pricing, reserving, and reinsurance strategies, while advancing your pr...
Reposted 2 weeks ago
Director, Managing Director- 401K Relationship Manager
$95K - $186K *
Join a team that's dedicated to building strong client relationships while leading strategic initiatives in the retirement industry. Leverage your expertise to educate clients, resolve issues, and dri...
2 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.