Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Licensed Therapist (LCSW, LPC, LMFT)
$80K - $101K *
Elevate patient care by providing expert therapy services in a flexible, supportive environment. Enjoy autonomy over your schedule while collaborating with a dedicated team to enhance mental health ou...
Today
Lead Analyst - Independent Assessment
$98K - $115K *
Lead independent assessments to evaluate and enhance the Bank's risk management practices, ensuring compliance with evolving regulatory standards while guiding a team of analysts in a dynamic environm...
5 days ago
$130K - $160K *
Elevate cloud security and reliability by leading DevOps practices across teams. You'll optimize AWS and GCP environments, enhance CI/CD pipelines, and ensure cost-effective engineering tools, driving...
1 week ago
Assoc Dir, Neuro Thought Leader Liaison (West region)
$190K - $225K *
Empower commercial strategies by building relationships with key thought leaders in rare neurological diseases, capturing insights to inform brand development and launch planning, and ensuring impactf...
Reposted 1 week ago
$80K - $95K *
Join a team that's dedicated to optimizing business office operations, overseeing financial counseling, billing, and collections. Lead initiatives to enhance cash flow and ensure compliance while mana...
3 weeks ago
$100K - $120K *
Join a team that's dedicated to providing comprehensive dental care in an underserved community. Collaborate with healthcare professionals to enhance patient outcomes while making a meaningful impact...
Reposted today
Senior Manager, Distribution & Revenue Strategy
$120K - $160K *
Drive strategic initiatives across partnerships, revenue, and operations. Collaborate with cross-functional leaders to tackle complex challenges in a fast-paced environment, ensuring effective executi...
Reposted today
Senior Regulatory Affairs Specialist
$83K - $103K *
Drive success in regulatory affairs by preparing critical submissions for medical and diagnostic devices. Oversee compliance with U.S. and international regulations while collaborating with cross-func...
Reposted 2 weeks ago
Sr. Account Executive, Enterprise
$112K - $150K *
Unlock potential by driving enterprise sales to Fortune 500 clients, managing end-to-end sales cycles, and fostering strategic relationships with C-level executives to deliver impactful SaaS complianc...
1 week ago
Software Engineer - Technology
$108K - $115K *
Unlock your potential as a full stack engineer, collaborating in an agile team to develop innovative applications and features, while leveraging cutting-edge AI technologies to enhance product offerin...
1 week ago
$84K - $127K *
Manage and resolve complex marine cargo and logistics claims, ensuring effective investigation, negotiation, and collaboration with stakeholders. Leverage technical expertise to analyze coverage and e...
Yesterday
Senior Consultant, Sage Intacct Implementation
$88K - $118K *
Join a team that's focused on driving operational excellence and technical solutions for clients. Lead transformative projects, enhance performance, and mentor junior consultants while ensuring succes...
Reposted 1 week ago
Snr Director, Global Controller
$160K - $190K *
Lead global accounting functions, ensuring integrity and efficiency in financial processes. Supervise teams across multiple locations while enhancing reporting accuracy and compliance within a growing...
Reposted today
Sr. Subservicing Oversight Analyst
$80K - $95K *
Transform client relationships by managing subservicing deliverables, ensuring compliance, and enhancing reporting processes. Collaborate with vendors and internal teams to support client needs and dr...
Today
Managing Director - Market Development & Revenue Growth (Guidewire InsuranceNow)
$180K - $220K *
Lead the charge in driving growth for our Guidewire InsuranceNow practice by developing strategic relationships, generating new business opportunities, and executing revenue strategies across the US i...
2 weeks ago
$100K - $135K *
Join us to evaluate and underwrite specialty insurance risks, fostering broker relationships and ensuring profitability while maintaining high standards of customer service and operational efficiency...
3 days ago
Product Manager, Personal Lines Homeowners - MSI
$95K - $115K *
Drive product management for homeowners insurance across multiple states, overseeing P&L, regulatory processes, and product enhancements. Collaborate with cross-functional teams to adapt strategies an...
Yesterday
$140K - $185K *
Elevate project success by leading commissioning efforts, managing field teams, and ensuring timely execution of complex projects. Utilize advanced decision-making and client interaction skills to dri...
1 week ago
Complex Claim Specialist, Excess & Surplus
$125K - $155K *
Analyze complex commercial claims, ensuring thorough investigations and effective resolutions. Collaborate with internal and external parties to manage litigated and non-litigated claims, leveraging s...
4 weeks ago
$100K - $120K *
Optimize clinical trial management by overseeing planning, execution, and compliance. Collaborate with cross-functional teams to ensure data integrity and drive innovative treatments while resolving c...
Today
$100K - $120K *
Execute clinical trial management activities, ensuring quality outcomes and compliance. Collaborate with cross-functional teams, manage timelines and budgets, and build strong relationships with stake...
Yesterday
$150K - $180K *
Engage with key healthcare clients to drive strategic account management, fostering relationships and delivering tailored solutions across GE HealthCare’s diverse portfolio, while leading cross-functi...
6 days ago
Senior Manager IGA Engineering (Sailpoint ISC)- Remote
$130K - $155K *
Drive the technical strategy for identity governance services, leading a team to enhance identity security across the organization. Collaborate with cross-functional teams to implement SailPoint solut...
6 days ago
Senior Associate, SALT - Income Franchise
$80K - $95K *
Join a team that's dedicated to supporting multi-state companies with state and local tax compliance. Collaborate with clients to navigate complex tax issues and ensure accurate filings while fosterin...
2 weeks ago
Senior Media Planner (Integrated)
$75K - $90K *
Elevate your career as you drive powerful media strategies, collaborating with teams and clients to optimize performance across various channels, leveraging insights for impactful digital campaigns in...
Reposted 1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.