Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Senior Counsel Jobs in Missouri

Sort By: Relevance

$80K - $101K *

Elevate patient care by providing expert therapy services in a flexible, supportive environment. Enjoy autonomy over your schedule while collaborating with a dedicated team to enhance mental health ou...

Today

  •   Less than 5 years exp.  •   Healthcare

$98K - $115K *

Lead independent assessments to evaluate and enhance the Bank's risk management practices, ensuring compliance with evolving regulatory standards while guiding a team of analysts in a dynamic environm...

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $160K *

Elevate cloud security and reliability by leading DevOps practices across teams. You'll optimize AWS and GCP environments, enhance CI/CD pipelines, and ensure cost-effective engineering tools, driving...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$190K - $225K *

Empower commercial strategies by building relationships with key thought leaders in rare neurological diseases, capturing insights to inform brand development and launch planning, and ensuring impactf...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a team that's dedicated to optimizing business office operations, overseeing financial counseling, billing, and collections. Lead initiatives to enhance cash flow and ensure compliance while mana...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Join a team that's dedicated to providing comprehensive dental care in an underserved community. Collaborate with healthcare professionals to enhance patient outcomes while making a meaningful impact...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$120K - $160K *

Drive strategic initiatives across partnerships, revenue, and operations. Collaborate with cross-functional leaders to tackle complex challenges in a fast-paced environment, ensuring effective executi...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$83K - $103K *

Drive success in regulatory affairs by preparing critical submissions for medical and diagnostic devices. Oversee compliance with U.S. and international regulations while collaborating with cross-func...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$112K - $150K *

Unlock potential by driving enterprise sales to Fortune 500 clients, managing end-to-end sales cycles, and fostering strategic relationships with C-level executives to deliver impactful SaaS complianc...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$108K - $115K *

Unlock your potential as a full stack engineer, collaborating in an agile team to develop innovative applications and features, while leveraging cutting-edge AI technologies to enhance product offerin...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$84K - $127K *

Manage and resolve complex marine cargo and logistics claims, ensuring effective investigation, negotiation, and collaboration with stakeholders. Leverage technical expertise to analyze coverage and e...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$88K - $118K *

Join a team that's focused on driving operational excellence and technical solutions for clients. Lead transformative projects, enhance performance, and mentor junior consultants while ensuring succes...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$160K - $190K *

Lead global accounting functions, ensuring integrity and efficiency in financial processes. Supervise teams across multiple locations while enhancing reporting accuracy and compliance within a growing...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Transform client relationships by managing subservicing deliverables, ensuring compliance, and enhancing reporting processes. Collaborate with vendors and internal teams to support client needs and dr...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$180K - $220K *

Lead the charge in driving growth for our Guidewire InsuranceNow practice by developing strategic relationships, generating new business opportunities, and executing revenue strategies across the US i...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$100K - $135K *

Join us to evaluate and underwrite specialty insurance risks, fostering broker relationships and ensuring profitability while maintaining high standards of customer service and operational efficiency...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Drive product management for homeowners insurance across multiple states, overseeing P&L, regulatory processes, and product enhancements. Collaborate with cross-functional teams to adapt strategies an...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$140K - $185K *

Elevate project success by leading commissioning efforts, managing field teams, and ensuring timely execution of complex projects. Utilize advanced decision-making and client interaction skills to dri...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$125K - $155K *

Analyze complex commercial claims, ensuring thorough investigations and effective resolutions. Collaborate with internal and external parties to manage litigated and non-litigated claims, leveraging s...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Optimize clinical trial management by overseeing planning, execution, and compliance. Collaborate with cross-functional teams to ensure data integrity and drive innovative treatments while resolving c...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Execute clinical trial management activities, ensuring quality outcomes and compliance. Collaborate with cross-functional teams, manage timelines and budgets, and build strong relationships with stake...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Engage with key healthcare clients to drive strategic account management, fostering relationships and delivering tailored solutions across GE HealthCare’s diverse portfolio, while leading cross-functi...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$130K - $155K *

Drive the technical strategy for identity governance services, leading a team to enhance identity security across the organization. Collaborate with cross-functional teams to implement SailPoint solut...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Join a team that's dedicated to supporting multi-state companies with state and local tax compliance. Collaborate with clients to navigate complex tax issues and ensure accurate filings while fosterin...

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$75K - $90K *

Elevate your career as you drive powerful media strategies, collaborating with teams and clients to optimize performance across various channels, leveraging insights for impactful digital campaigns in...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.