Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Clinical Neuropsychologist Outpatient
$92K - $110K *
Lead neuropsychological assessments for outpatients, collaborating with interdisciplinary teams to enhance recovery post-stroke, brain injury, or surgery. Play a key role in delivering high-quality ca...
1 week ago
$150K - $200K *
Accelerate progress at the forefront of product innovation, leading a team to drive strategy and customer experience for a key transaction management platform while embedding AI to enhance efficiency...
1 week ago
$110K - $130K *
Elevate your career by collaborating with cross-functional teams to enhance business operations, streamline processes, and drive value through effective analysis and documentation. Your expertise will...
2 weeks ago
$110K - $130K *
Lead the creation and enhancement of high-quality technical documentation, collaborating with cross-functional teams to translate complex information into user-friendly content that improves the overa...
2 weeks ago
Sr Life Underwriting Business Systems Analyst
$85K - $100K *
Champion life underwriting transformation initiatives by analyzing requirements, facilitating project lifecycles, and collaborating with cross-functional teams to enhance operational excellence and im...
1 week ago
Branch Operations Supervisor- Commercial Insurance (Remote)
$105K - $125K *
Lead and oversee Account Management teams, ensuring operational excellence and compliance while fostering staff development and enhancing client relationships in a dynamic remote environment...
3 days ago
Senior Architect (Mission Critical)
$118K - $147K *
Drive high-stakes architectural design for complex technology projects, ensuring innovative solutions from concept through execution while collaborating with leading global firms in a multidisciplinar...
Reposted 2 weeks ago
$95K - $115K *
Drive the resolution of complex surety disputes by conducting technical analyses, collaborating with consultants, and advising on construction and claims management, while leading teams to assess risk...
Reposted 6 days ago
Executive Planning Consultant I - Remote
$79K - $153K *
Unlock potential by building strong relationships with executives, co-creating tailored wealth planning solutions. Collaborate with a cross-functional team to address complex financial needs and enhan...
4 days ago
Executive Planning Consultant I - Remote
$79K - $153K *
Shape the future of executive wealth planning by building strong relationships with clients. Leverage your expertise to deliver tailored financial solutions, collaborating with a dedicated team to mee...
3 weeks ago
Senior Human Resources Business Partner
$110K - $130K *
Champion strategic HR initiatives that drive organizational design, talent development, and change management. Collaborate with senior leaders to enhance employee experience and align workforce planni...
3 weeks ago
Senior Associate, Strategy & Operations
$125K - $155K *
Champion strategic initiatives by connecting breakthrough chemistry with market opportunities. Collaborate across teams to drive government partnerships, proposals, and commercial growth, transforming...
3 weeks ago
Vice President, Executive Planning Consultant - Northern California
$96K - $210K *
Lead personalized financial planning for senior executives, integrating workplace benefits into comprehensive strategies. Drive client engagement and satisfaction while managing relationships and expa...
6 days ago
$120K - $145K *
Lead cross-functional teams to develop and execute a strategic product roadmap, integrating market insights and performance metrics to drive customer-centric solutions in the diagnostics and genomics...
4 weeks ago
Director, Sustainability Regulatory Advisory
$200K - $230K *
Shape the future of sustainability advisory by leading complex engagements, driving business growth, and delivering high-quality regulatory compliance solutions in a rapidly evolving ESG landscape...
1 week ago
Professional Services Engineer
$100K - $120K *
Deliver exceptional consulting services by managing client implementations, diagnosing technical issues, and providing tailored solutions. Collaborate with cross-functional teams to ensure seamless in...
2 weeks ago
$190K - $200K *
Elevate your career by driving sales strategy and execution for a dynamic SaaS portfolio. Lead a high-performing team to achieve revenue growth, optimize pipeline management, and enhance customer acqu...
1 week ago
Manager, Partnerships & Network Development (West Coast)
$95K - $115K *
Lead and develop a high-performing team to expand behavioral healthcare access. Drive regional referral growth through strategic partnerships, data-driven decision-making, and effective outreach while...
1 week ago
$120K - $145K *
Lead the charge in multidisciplinary design delivery for data center projects, ensuring buildable, cost-effective designs from planning through construction. Collaborate with teams to meet tenant need...
2 weeks ago
Sr Director, Product Management
$160K - $200K *
Drive the evolution of dealer marketing solutions by leading product management efforts, overseeing current offerings, and defining a next-gen platform that enhances customer engagement and retention...
5 days ago
Client Relationship Manager within Global Workplace Programs
$100K - $166K *
Transform workplace strategies by partnering with leaders to align business goals with innovative real estate solutions. Drive integrated planning across diverse portfolios, ensuring optimal employee...
5 days ago
Staff Software Engineer, Applied AI
$160K - $200K *
Join a team that's redefining operational efficiency by architecting robust internal tools and applying AI to real-world challenges. You'll lead technical direction, drive impactful decisions, and enh...
1 week ago
Senior Reward & Mobility Manager
$180K - $200K *
Accelerate progress at a multinational level by driving the reward and global mobility agenda. Lead the design and governance of compensation structures, ensuring alignment with business needs while p...
Reposted 1 week ago
$73K - $88K *
Accelerate progress at expanding customer accounts by driving annual recurring revenue and enhancing retention through structured sales strategies and digital engagement, while managing a high-volume...
1 week ago
Director, Business Strategy & Operations, Research
$192K - $288K *
Join a team that's driving strategic initiatives in Neuroscience and Oncology. In this pivotal role, you'll partner with leadership to enhance operations, manage budgets, and streamline workforce plan...
5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.