Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Senior Director, Business Management & Execution Lead
$170K - $200K *
Champion operational excellence by leading business unit strategies, enhancing performance management, and driving cross-functional collaboration to achieve enterprise goals and scalable solutions...
Yesterday
Venture Capital Fund Controller
$150K - $180K *
Transform financial operations by leading fund administration, ensuring compliance, and mentoring teams while managing complex investment transactions and audits for venture capital funds...
1 week ago
SVP -Business Development Officer -SBA & CRE
$150K - $180K *
Transform your career by driving growth in commercial real estate financing. This role focuses on originating and structuring loans while building strong relationships with clients and industry profes...
Reposted 1 week ago
$80K - $95K *
Transform the accounting function by overseeing monthly closes, ensuring compliance, and managing tax processes. Collaborate with finance leadership to drive accurate reporting and support strategic p...
1 week ago
Regional Vice President - Retirement Mid Markets-(N. New Jersey)
$90K - $100K *
Reimagine retirement solutions by driving sales in small to mid-sized markets. Collaborate with financial intermediaries to build relationships and achieve company objectives while managing a dynamic...
4 weeks ago
Senior/National Account Director, Market Access
$158K - $250K *
Join a team that's redefining market access strategies in the pharma industry. Leverage your expertise in managed care and payer relationships to drive coverage and reimbursement for innovative therap...
5 days ago
Senior Consultant, EHS Compliance
$80K - $95K *
Deliver critical EHS compliance solutions, navigate regulatory challenges, and advance sustainable practices while collaborating with project teams and clients on diverse environmental projects, ensur...
Reposted yesterday
Senior Global Product Compliance Specialist
$135K - $180K *
Drive compliance excellence by managing global product projects across diverse markets. Collaborate with teams to ensure adherence to regulations for dietary supplements, foods, cosmetics, and medical...
2 weeks ago
Executive Director Senior Lead Product Manager Client Management Salesforce CRM
$139K - $239K *
Empower client management by leading product vision and execution across key capabilities. Collaborate with cross-functional teams to enhance advisor and client experiences while ensuring compliance a...
Reposted 3 days ago
Executive Director Senior Lead Product Manager Client Management Salesforce CRM
$139K - $239K *
Accelerate progress at the forefront of product management, leading initiatives that enhance client management capabilities. Collaborate with cross-functional teams to define vision, prioritize roadma...
Reposted 1 week ago
$97K - $118K *
Lead the charge in developing and executing strategic sales initiatives for large accounts, fostering key relationships to drive long-term revenue growth and market penetration while collaborating acr...
3 weeks ago
Senior Sales Compensation Analyst - Software Sales
$110K - $130K *
Drive sales performance by managing comprehensive compensation strategies that align with company goals. Collaborate across teams to design and implement effective plans, analyze data trends, and ensu...
Reposted 1 week ago
$120K - $145K *
Take ownership of automating workflows across teams by building AI agents using Claude and Microsoft Copilot. Collaborate with various departments to identify automation opportunities, ensuring securi...
3 weeks ago
Sr. Consultant / Project Manager
$95K - $115K *
Empower client success by leading software implementation projects, fostering relationships, and driving innovation. Manage timelines and deliverables while ensuring satisfaction through expert guidan...
6 days ago
Senior Associate Scientist, Investigations and Compliance Specialist
$68K - $114K *
Optimize quality investigations by ensuring compliance with standards, analyzing data, and collaborating with teams to enhance processes. Drive improvements in GMP microbiology through proactive engag...
1 week ago
$195K - $277K *
Drive innovative clinical oncology studies by designing protocols, collaborating with teams, and ensuring compliance with regulations. Leverage expertise to analyze data, support publications, and mai...
3 weeks ago
Large Enterprise Business Development Executive GBS Sales Practice
$102K - $147K *
Accelerate growth by developing strategic relationships with C-level executives to identify and secure new business opportunities, driving the entire sales cycle in a high-stakes environment focused o...
Reposted 3 weeks ago
$100K - $120K *
Empower your career by leading a dynamic sales team, mentoring new talent, and building lasting client relationships while driving business growth through tailored insurance solutions...
Reposted yesterday
$100K - $120K *
Join a team that's dedicated to empowering clients through exceptional sales leadership. Leverage your extensive experience to train new team members while managing your own client relationships and d...
Reposted yesterday
$100K - $120K *
Elevate your career by leading a dynamic sales team, training new members, and building lasting client relationships. Utilize your extensive sales experience to implement proven strategies and provide...
2 days ago
Senior Analyst - Property & Specialty Product
$80K - $95K *
Optimize product performance by analyzing data, managing initiatives, and collaborating with teams. Your insights will shape strategies for Motorcycle, RV, Watercraft, and Classic Car products, drivin...
1 week ago
$95K - $115K *
Advance clinical trial success by providing strategic expertise in operations and collaboration. Optimize processes, develop budgets, and drive initiatives to enhance efficiency while ensuring alignme...
Reposted 2 days ago
Treasury Manager, Capital Markets
$110K - $130K *
Manage key capital markets activities, overseeing debt operations, cash flow forecasting, and financial risk management. Collaborate with stakeholders to prepare executive materials and support pensio...
6 days ago
$85K - $115K *
Elevate financial accuracy by leading revenue accounting and accounts receivable processes. Own revenue-cycle close activities, collaborate cross-functionally, and drive improvements in a fast-paced e...
1 week ago
Healthcare & Medical Malpractice Associate Attorney
$100K - $120K *
Transform your legal career by managing complex medical malpractice cases. Leverage your expertise in litigation while collaborating with a dynamic team to deliver exceptional results for healthcare p...
2 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.