Quality Systems Manager Jobs

Explore Quality Systems Manager opportunities with employers seeking experienced professionals to lead quality programs, strengthen compliance, and improve business processes. Ladders features vetted professional jobs paying $100,000 or more, including roles for quality leaders across regulated and highly technical industries.

What Does a Quality Systems Manager Do?

Quality Systems Managers develop and maintain the policies, procedures, and processes that help organizations consistently meet customer expectations and applicable standards. They may oversee quality management systems (QMS), coordinate audits, monitor corrective and preventive actions, manage documentation, and partner with teams across operations, engineering, manufacturing, and regulatory affairs.

Common Responsibilities

  • Lead the design, implementation, and ongoing improvement of quality management systems.
  • Prepare for internal, customer, and third-party audits and help resolve audit findings.
  • Track nonconformances, corrective and preventive actions, and quality performance metrics.
  • Maintain controlled procedures, records, and training programs.
  • Guide teams on quality standards, regulatory requirements, and risk management.
  • Identify process improvements that reduce defects and strengthen product or service reliability.

Qualifications and Skills

Employers commonly seek a bachelor's degree in engineering, science, business, or a related field, along with substantial experience in quality assurance or quality systems. Requirements vary by industry and role. Useful strengths include knowledge of quality standards and audit practices, analytical problem-solving, clear communication, project leadership, and the ability to influence cross-functional teams. Certifications such as Certified Quality Manager or auditor credentials may be valued for some positions.

Industries and Career Opportunities

Quality Systems Managers work in fields where consistent processes, customer confidence, and compliance matter, including medical devices, pharmaceuticals, aerospace, automotive, electronics, food production, and industrial manufacturing. Depending on the employer, the role may focus on a facility, product line, business unit, or enterprise-wide quality system, with opportunities to advance into director-level quality, compliance, or operational leadership.

Find Quality Systems Manager Jobs on Ladders

Search Ladders for vetted Quality Systems Manager jobs with salaries of $100,000 or more. Compare opportunities by industry, location, and seniority to find a role that aligns with your experience and career goals.

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$150K - $180K *

Innovate testing and automation systems to enhance software release confidence. Lead technical direction, integrate AI for efficiency, and ensure reliable verification processes while fostering collab...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Lead the charge in transforming system designs and guiding project engineering teams to optimize solutions and drive profitability while ensuring technical excellence and strong vendor alignment throu...

Detroit, MIRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Staffing

$80K - $90K *

Join a team that's transforming customer onboarding by leading complex implementations, aligning stakeholders, and delivering scalable solutions that drive success and revenue. Your expertise will bri...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$165K - $185K *

Manage clinical trial operations for early-phase gene-editing studies, overseeing execution from start-up to close-out. Collaborate with internal teams, CROs, and vendors to ensure timelines, budgets...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Deliver leadership and governance for global clinical study management, ensuring projects meet timelines and budgets while fostering collaboration and operational excellence across teams and stakehold...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $183K *

Manage the advancement of clinical evidence strategies to support regulatory submissions and product lifecycle management. Collaborate across functions to optimize clinical evaluations and enhance mar...

Portage, MIRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Advance software development by leading projects, mentoring engineers, and architecting solutions. Collaborate across teams to enhance performance and functionality while staying updated on technology...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$140K - $175K *

Optimize data analytics support for lab production operations by leading a dedicated team in a dynamic environment. Drive innovation, ensure compliance, and enhance operational effectiveness while mak...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$114K - $190K *

Oversee project management for innovative small modular reactor deployments, ensuring timely delivery, customer satisfaction, and effective risk mitigation. Collaborate with multidisciplinary teams an...

Wilmington, NCRemote

Reposted today

  •   5 - 7 years exp.  •   Business Services

$218K - $335K *

Shape the future of autonomous driving by leading a talented engineering team to build robust evaluation platforms and metrics that ensure AV performance is optimized, scalable, and data-driven, foste...

Sunnyvale, CARemote

Reposted today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$166K - $249K *

Shape the future of AI in healthcare by defining and executing a strategic roadmap that integrates intelligent solutions into clinical workflows, ensuring safety and efficiency while collaborating wit...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $150K *

Transform your career by leading complex, multi-billion-dollar power generation projects. Oversee all phases from development to execution, ensuring quality, budget, and schedule adherence while foste...

Phoenix, AZRemote

Today

  •   8 - 10 years exp.  •   Energy & Utilities

$150K - $190K *

Help us shape the future of AI operations by leading a dynamic team focused on innovative solutions, strategic partnerships, and technical excellence in agentic environments. Drive growth and operatio...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Join us to drive strategic growth by managing key accounts, building executive relationships, and leading complex deals. Shape multi-year strategies and collaborate with a virtual team to deliver impa...

Waltham, MARemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Empower healthcare IT delivery by managing a dynamic team, ensuring operational excellence, and driving EMR performance. Collaborate with clinical stakeholders to enhance patient care through effectiv...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$138K - $173K *

Join a team that's transforming manufacturing through digital solutions. Lead cross-functional initiatives, drive process improvements, and ensure seamless integration of technology to enhance operati...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Real Estate & Construction

$150K - $180K *

Lead the charge in driving sales growth and strategic partnerships within the packaging sector. Oversee a high-performing team, manage customer relationships, and optimize processes to achieve revenue...

Indiana, USRemote

2 weeks ago

  •   8 - 10 years exp.  •   Food & Beverages

$145K - $190K *

Lead and execute complex commissioning processes in mission-critical environments. Utilize deep technical knowledge to deliver strategic plans and mentor teams while managing multiple projects effecti...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$150K - $190K *

Join a transformative team dedicated to driving strategic client growth and enterprise adoption of innovative solutions, while fostering executive relationships and orchestrating cross-functional init...

Tucson, AZRemote

Reposted 1 month ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $149K *

Unlock potential by delivering advanced analytics and reporting solutions that enhance clinical outcomes and operational efficiency. Collaborate with stakeholders to bridge clinical operations and IT...

Norfolk, VARemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$240K - $310K *

Elevate your career as you lead a team of technical experts to develop innovative strategies that drive customer engagement and support business growth across diverse sectors...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$80K - $100K *

Join a dynamic team to manage complex projects, ensuring quality control and timely deliverables while coordinating with engineers and stakeholders. Drive continuous improvement and provide analytical...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $100K *

Contribute to the development and integration of mission-critical systems, applying systems engineering principles to ensure high reliability and security. Collaborate across teams to support the enti...

Pittsfield, MARemote

Yesterday

  •   Less than 5 years exp.  •   Aerospace & Defense

$70K - $103K *

Optimize SAP Time Management solutions by configuring, testing, and supporting integrations. Collaborate with teams to enhance processes, resolve issues, and deliver training, ensuring effective timek...

Virginia, USRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$100K - $105K *

Drive customer success by managing accounts, achieving sales targets, and implementing RQI Portfolio solutions to enhance hospital systems, ensuring engagement and retention through meaningful relatio...

New York, NYRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Quality Systems Manager do?question toggle

    A Quality Systems Manager oversees the processes, documentation, audits, and improvement activities that help an organization meet quality standards, regulatory requirements, and customer expectations.

  • What qualifications are commonly required for Quality Systems Manager jobs?question toggle

    Many positions seek a bachelor's degree in a relevant field and significant experience in quality assurance, quality systems, or a regulated industry. Employers may also value audit expertise, standards knowledge, leadership skills, and relevant certifications.

  • Which industries hire Quality Systems Managers?question toggle

    Hiring industries include medical devices, pharmaceuticals, aerospace, automotive, electronics, food production, and manufacturing, as well as other sectors with complex quality or compliance requirements.

  • How much do Quality Systems Manager jobs on Ladders pay?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Actual compensation varies by employer, location, industry, responsibilities, and experience.

  • What skills are important for a Quality Systems Manager?question toggle

    Commonly valued skills include quality management system expertise, audit planning, corrective and preventive action management, regulatory knowledge, data analysis, process improvement, communication, and cross-functional leadership.