Quality Systems Manager Jobs

Explore Quality Systems Manager jobs for experienced professionals ready to lead quality programs and strengthen operational performance. These roles oversee the systems, processes, and standards that help organizations deliver reliable products and services while meeting regulatory and customer requirements. Ladders features vetted professional opportunities with salaries of $100,000 or more.

What Does a Quality Systems Manager Do?

Quality Systems Managers develop and maintain quality management systems, guide internal and external audits, and help teams meet applicable standards and regulations. Depending on the organization, responsibilities may include managing corrective and preventive actions, tracking quality metrics, investigating nonconformances, preparing documentation, and coordinating quality initiatives across departments or sites.

Skills and Qualifications

Employers commonly seek leaders with experience in quality assurance, quality management systems, audit readiness, risk management, and process improvement. Familiarity with relevant industry standards and regulatory requirements can be important, particularly in regulated sectors. Strong communication, analytical thinking, project management, and team leadership skills help managers turn quality goals into practical, consistent processes.

Industries and Career Opportunities

Quality Systems Managers work across industries such as manufacturing, life sciences, healthcare, technology, aerospace, and consumer products. The scope of a role can range from overseeing a single facility’s quality system to setting strategy across multiple locations. Related career paths may include quality assurance leadership, compliance management, regulatory affairs, and operational excellence.

Find Quality Systems Manager Jobs on Ladders

Search Ladders for Quality Systems Manager jobs and discover vetted roles offering $100,000 or more. Explore opportunities that match your leadership experience, industry background, and career goals, and take the next step toward a senior quality management position.

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$91K - $120K *

Drive quality assurance and compliance for GxP computerized systems, ensuring data integrity and regulatory adherence throughout the system lifecycle. Collaborate with cross-functional teams to enhanc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$91K - $120K *

Drive quality assurance and compliance for GxP computerized systems, ensuring data integrity and regulatory adherence throughout the system lifecycle. Collaborate with cross-functional teams to enhanc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$152K - $175K *

Shape and enhance the global Quality Management System for medical devices by driving compliance, governance, and continuous improvement while leading a dedicated team across multiple sites to meet re...

Massachusetts, USRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $172K *

Unlock potential by leading the design and deployment of a global Quality Management System, ensuring compliance and operational excellence across multiple aerospace sites while fostering collaboratio...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $140K *

Pioneer GxP compliance in digital quality management, ensuring software and AI products meet regulatory standards. Collaborate with stakeholders to enhance quality processes and support audits, drivin...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Drive quality assurance initiatives by overseeing computer system validation processes, ensuring compliance with GxP regulations, and collaborating with cross-functional teams to enhance validation pr...

Kentucky, USRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Lead the charge in ensuring quality assurance for transport and packaging validation, collaborating with cross-functional teams to uphold compliance and readiness for commercial launch while managing...

New York, USRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$126K - $145K *

Join a team that's dedicated to ensuring compliance and quality in GxP computer systems. Oversee validation and lifecycle management across clinical, quality, and manufacturing environments while coll...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Drive IT quality and compliance initiatives, managing audits and ensuring adherence to regulatory standards. Collaborate with global teams to enhance operational performance and support career develop...

Durham, NCRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $165K *

Bring your expertise to define and deliver enterprise integration products, optimizing data flow and connectivity across manufacturing environments. Collaborate with cross-functional teams to enhance...

Detroit, MIRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$175K - $400K *

Join a team that's shaping the future of digital supply chain management. You'll architect and optimize ERP, PLM, and inventory systems, ensuring data integrity and operational scalability across glob...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Transform workplace safety by leading initiatives, conducting assessments, and fostering a culture of compliance and performance. Collaborate with teams to implement effective health and safety strate...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$125K - $150K *

Lead the design and implementation of GxP-compliant Quality applications, ensuring data integrity and regulatory compliance while mentoring junior team members and driving continuous improvement in a...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Optimize quality operations for large-scale data pipelines, ensuring high standards and consistency across diverse datasets. Lead a team to enhance efficiency and reliability in audio data processing...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $110K *

Join a dynamic team in managing project lifecycles by applying proven methodologies. You will lead diverse project teams, enhance client satisfaction, and promote continuous improvement while driving...

Philadelphia, PARemote

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$162K - $290K *

Drive innovation in quality engineering by leading a multidisciplinary team to enhance test infrastructure and ensure scalable, reliable, and high-quality customer experiences across our cloud solutio...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$190K - $228K *

Drive enterprise Quality and Regulatory governance for U.S. operations, ensuring compliance with FDA regulations and overseeing manufacturing quality in the therapeutic radiopharmaceutical sector whil...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $100K *

Manage and execute complex LIMS implementations for public health and environmental labs. Collaborate with cross-functional teams to ensure project success, stakeholder alignment, and high-quality out...

Tucson, AZRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Manage clinical trial operations, ensuring compliance and performance across protocols. Oversee submissions, budgets, and team coordination while collaborating with internal and external stakeholders...

Quebec, CARemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform quality assurance by leading a dedicated team, ensuring compliance, and managing complex client projects. Drive excellence in drug importation and quality documentation while fostering stron...

Ontario, CARemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$134K - $192K *

Lead the design and optimization of global service systems and analytics, driving operational excellence and customer success. Collaborate across departments to implement scalable solutions that enhan...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $135K *

Champion a global HSEQ strategy, fostering compliance and quality across operational regions while developing a proactive safety culture and optimizing customer service delivery in the solar and stora...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$130K *

Partner with us to innovate and transform Quality & Regulatory operations through technology and data analytics. Drive automation, improve efficiency, and foster effective digital solutions that enhan...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Elevate the quality assurance process by managing UAT, bug triage, and CI/CD systems. Collaborate with engineering teams to ensure seamless communication and proactive quality management throughout th...

Toronto, ONRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$130K - $160K *

Lead quality operations to ensure data accuracy and compliance in healthcare. Drive improvements through audits, data analysis, and technology integration, fostering a culture of excellence across tea...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Quality Systems Manager do?question toggle

    A Quality Systems Manager oversees the processes and documentation an organization uses to meet quality, regulatory, and customer requirements. Duties often include managing audits, corrective and preventive actions, quality metrics, and continuous improvement initiatives.

  • What qualifications are typically required for Quality Systems Manager jobs?question toggle

    Requirements vary by employer and industry, but roles often call for experience in quality assurance or quality management systems, knowledge of applicable standards and regulations, and strong leadership, analytical, communication, and project management skills.

  • Which industries hire Quality Systems Managers?question toggle

    Employers hire Quality Systems Managers in fields including manufacturing, life sciences, healthcare, aerospace, technology, and consumer products. The specific standards and regulatory knowledge required depend on the industry.

  • How much do Quality Systems Manager jobs pay?question toggle

    Compensation varies by location, industry, experience, and the scope of the role. Ladders focuses on vetted professional jobs paying $100,000 or more, so candidates can explore opportunities at that salary level.

  • Where can I find Quality Systems Manager jobs paying $100,000 or more?question toggle

    Browse Quality Systems Manager listings on Ladders to explore vetted professional opportunities paying $100,000 or more.