Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$189K - $213K *

Innovate in the realm of neurovascular and endovascular products. As a Principal Engineer, lead design projects, mentor R&D teams, and propel product enhancements to meet customer needs and regulatory...

4 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$160K - $180K *

Bring your expertise to developing innovative formulations for nonclinical studies. Collaborate with cross-functional teams to design and manage studies, ensuring timely supply of high-quality drug fo...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Lead the charge in managing capital projects to optimize budgets, schedules, and quality. Apply your engineering expertise in a multi-disciplinary role, ensuring compliance and enhancing efficiency fr...

3 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$100K - $130K *

Join a dynamic team as you lead QC operations in analytical testing for clinical development programs. Your expertise will drive compliance, strategic execution, and enhance collaboration across funct...

Edmonton, ABIn-Person

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Lead the charge in managing Quality Control Laboratory Operations while ensuring compliance with GxP regulations. Oversee stability programs, QC sample management, and contribute to product commercial...

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$115K - $172K *

Empower analytical advancements by translating manual lab workflows into scalable, automation-ready processes. Collaborate with cross-functional teams to optimize laboratory solutions and drive innova...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Lead the Environmental Simulation and Reliability Lab, overseeing all aspects from operations to customer relationships. Engage with defense clients while driving testing programs to MIL-STD-810 and D...

3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$120K - $150K *

Join a fast-track global leadership program focused on developing future leaders through hands-on training in production operations, team management, and project execution across international sites...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$105K - $120K *

Lead complex research and evaluation projects, mentor multidisciplinary teams, and drive new business opportunities. Oversee project management and collaborate with stakeholders to deliver high-qualit...

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $150K *

Accelerate progress at our leading biologics manufacturing sites by driving operational excellence and team leadership. Gain hands-on experience in downstream processes while shaping the future of glo...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$65K - $169K *

Join a transformative team in quality operations, conducting advanced analyses to support drug safety, authentication, and regulatory compliance while collaborating on innovative analytical methods an...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $110K *

Unlock your potential by supporting process development for intermediates and APIs, ensuring compliance with quality standards, and collaborating across teams in a dynamic laboratory setting. Drive in...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $123K *

Drive the optimization and implementation of high-throughput protein expression platforms, overseeing operations and innovation in a fast-paced R&D environment while mentoring junior scientists and co...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Transform oral solid dosage forms as a Principal Scientist, leading HME and ASD technologies from preclinical to commercial. Collaborate on formulation strategies, enhance client relationships, and ap...

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Shape the future of renewable fuels by leading catalyst synthesis and characterization for heterogeneous catalysis. Collaborate with teams to deliver actionable data, ensuring robust support for innov...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$112K - $168K *

Unlock potential by leading analytical development in cell therapy. Drive method qualification, data analysis, and cross-functional collaboration to enhance gene therapy processes. Contribute to impac...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Transform national security capabilities as a Principal Software Engineer. Lead in developing complex software solutions, optimize performance across various languages, and mentor junior engineers whi...

Yesterday

  •   Less than 5 years exp.  •   Aerospace & Defense

$80K - $118K *

Pioneer innovative automated research instruments, enhancing next-gen AI-driven capabilities. Collaborate across disciplines to improve solid-state material processing, driving scientific discovery th...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Champion innovative solutions in engineered biologics development, transforming autoimmune therapies through advanced protein design and collaborative in vitro and in vivo studies from concept to prec...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$137K - $166K *

Unlock potential by leading the development of innovative analytical methods for RNA therapeutics. Collaborate across teams to advance product development while using advanced chromatographic techniqu...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $180K *

Unlock potential by leading transformative proteomics initiatives to boost our targeted protein degradation platform. Collaborate cross-functionally to enhance workflows and infrastructure while mento...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$123K - $161K *

Take ownership of analytical method development and material characterization, ensuring compliance with cGMP standards. Collaborate across departments, manage reference standards, and leverage mass sp...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$89K - $139K *

Champion the development of innovative medical isotope products by leading R&D projects, collaborating with cross-functional teams, and ensuring compliance with industry standards to successfully brin...

Ottawa, ONIn-Person

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$105K - $130K *

Lead the charge in managing complex scientific projects, ensuring successful delivery through collaboration with internal and external stakeholders, while maintaining quality and compliance with regul...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $110K *

Transform material innovation by leading testing protocols, guiding lab operations, and collaborating with cross-functional teams. Drive product development with advanced materials while ensuring opti...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.