Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$145K - $155K *

Elevate your career as a Senior Oligonucleotide Scientist, driving innovation in oligonucleotide synthesis and purification. Mentor teams and lead groundbreaking projects from early discovery to clini...

Reposted yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$127K - $179K *

Transform product development by embedding digital technologies and AI into R&D processes. Lead digital enablement, enhance scientific workflows, and drive innovation with cross-functional teams to im...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$127K - $179K *

Unlock potential by leading digital transformation initiatives in R&D. Spearhead AI capabilities and data-driven solutions to enhance product development efficiency and collaboration while ensuring co...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $118K *

Join a dynamic team to enhance materials research through characterization workflows, ensuring efficient operations and precise data delivery while collaborating with scientists and engineers for high...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$117K - $146K *

Elevate your career as a Principal Chemist, leading analytical research and development initiatives. Utilize advanced chemistry techniques to solve real-world challenges while collaborating with a ded...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$204K - $223K *

Transform drug discovery processes by leveraging advanced computational chemistry, AI/ML technologies, and collaboration across disciplines to discover novel therapeutic molecules for challenging targ...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Lead complex biologics projects as a scientific liaison, driving coordination and execution of bioanalytical studies with a focus on large molecules, ensuring compliance and delivering high-quality da...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $115K *

Unlock potential by leading complex metabolite identification and elucidation efforts. Collaborate on innovative studies to support drug discovery from early development to IND stages while ensuring r...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$139K - $149K *

Join a team that's pioneering innovative biomarker strategies in the therapeutic landscape. Lead impactful research and drive experimental design in preclinical models, as you advance compelling new p...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Develop and execute innovative assays assessing engineered microbial functions. Collaborate with cross-functional teams to drive strategic decisions and enhance research initiatives, delivering impact...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$211K - $264K *

Join a team that's dedicated to safety innovation and excellence, leading core processes in global patient safety. Collaborate with cross-functional stakeholders to enhance pharmacovigilance strategie...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$65K - $169K *

Drive cleanroom environmental monitoring programs, ensuring compliance, data integrity, and inspection readiness. Lead a team, partner across departments, and support manufacturing operations in a sta...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$65K - $169K *

Lead the charge in establishing and overseeing the Cleanroom EM program while ensuring compliance with GMP standards. Engage collaboratively across departments to support production readiness and main...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Contribute to innovative drug discovery by applying advanced synthetic methodologies and collaborating with a dynamic team on multi-step synthesis and optimization processes to advance medicinal chemi...

Montreal, QCIn-Person

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Lead the charge in complex environmental remediation projects, guiding multidisciplinary teams and advising clients on regulatory and risk considerations to develop sustainable solutions for contamina...

1 week ago

  •   15+ years exp.  •   Energy & Utilities

$90K - $120K *

Join us as you lead the development of bioanalytical methods for preclinical and clinical programs, providing expertise in large molecule analysis and project management to support drug development ca...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$122K - $147K *

Innovate scientific solutions while leading and mentoring a team of researchers. Drive experimental design, optimize platform performance, and collaborate cross-functionally to enhance research outcom...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Lead the charge in technical leadership, client relationship management, and project delivery. Ensure projects are completed safely and on time while mentoring staff and driving business growth in env...

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$80K - $110K *

Champion project delivery by leading teams, ensuring environmental compliance, and driving business growth through client engagement and technical excellence in a fast-paced consulting environment...

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$88K - $133K *

Join a team that's dedicated to environmental protection and data accuracy, tackling complex challenges as a Project Chemist. Collaborate on QA project plans, ensuring high-quality data for a sustaina...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$117K - $184K *

Engineer cutting-edge biocatalytic solutions to advance drug development and therapeutic innovations by leveraging interdisciplinary collaboration and deep scientific expertise to solve complex bioche...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Lead formulation strategies for innovative long-acting oral drug delivery solutions in a fast-paced biotech environment. Oversee product development from feasibility to manufacture, guiding teams on o...

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $120K *

Accelerate progress at the forefront of biopharmaceutical research, leading antibody development and protein production initiatives for novel oncology targets. Collaborate in a dynamic environment to...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$196K - $314K *

Empower the future of embedded systems by integrating AI technologies into firmware engineering. Lead initiatives on AI adoption, tool development, and scalable infrastructure while collaborating acro...

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $115K *

Join a team that's driving innovative laboratory solutions, performing complex testing, and mentoring junior scientists. Lead method development and execution while ensuring data accuracy and complian...

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.