Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
Senior Scientist, Oligonucleotide
$145K - $155K *
Elevate your career as a Senior Oligonucleotide Scientist, driving innovation in oligonucleotide synthesis and purification. Mentor teams and lead groundbreaking projects from early discovery to clini...
Reposted yesterday
Principal Scientist, Digital Enablement
$127K - $179K *
Transform product development by embedding digital technologies and AI into R&D processes. Lead digital enablement, enhance scientific workflows, and drive innovation with cross-functional teams to im...
3 days ago
Principal Scientist, Digital Enablement
$127K - $179K *
Unlock potential by leading digital transformation initiatives in R&D. Spearhead AI capabilities and data-driven solutions to enhance product development efficiency and collaboration while ensuring co...
3 days ago
Senior Research Associate / Associate Scientist, Characterization
$80K - $118K *
Join a dynamic team to enhance materials research through characterization workflows, ensuring efficient operations and precise data delivery while collaborating with scientists and engineers for high...
1 week ago
Principal Chemist - Analytical Chemistry
$117K - $146K *
Elevate your career as a Principal Chemist, leading analytical research and development initiatives. Utilize advanced chemistry techniques to solve real-world challenges while collaborating with a ded...
2 weeks ago
Principal Scientist, Computational Chemistry
$204K - $223K *
Transform drug discovery processes by leveraging advanced computational chemistry, AI/ML technologies, and collaboration across disciplines to discover novel therapeutic molecules for challenging targ...
Reposted 2 weeks ago
Scientific Program Manager & Biologics SME
$100K - $130K *
Lead complex biologics projects as a scientific liaison, driving coordination and execution of bioanalytical studies with a focus on large molecules, ensuring compliance and delivering high-quality da...
Reposted 2 weeks ago
$100K - $115K *
Unlock potential by leading complex metabolite identification and elucidation efforts. Collaborate on innovative studies to support drug discovery from early development to IND stages while ensuring r...
3 weeks ago
Senior Scientist, Translational Research
$139K - $149K *
Join a team that's pioneering innovative biomarker strategies in the therapeutic landscape. Lead impactful research and drive experimental design in preclinical models, as you advance compelling new p...
1 week ago
Scientist/Senior Scientist, Microbiology
$95K - $115K *
Develop and execute innovative assays assessing engineered microbial functions. Collaborate with cross-functional teams to drive strategic decisions and enhance research initiatives, delivering impact...
Today
Principal Scientist, Global Patient Safety Surveillance
$211K - $264K *
Join a team that's dedicated to safety innovation and excellence, leading core processes in global patient safety. Collaborate with cross-functional stakeholders to enhance pharmacovigilance strategie...
2 weeks ago
Principal Scientist GMP Environmental Monitoring Lilly Medicine Foundry
$65K - $169K *
Drive cleanroom environmental monitoring programs, ensuring compliance, data integrity, and inspection readiness. Lead a team, partner across departments, and support manufacturing operations in a sta...
1 week ago
Principal Scientist GMP Environmental Monitoring Lilly Medicine Foundry
$65K - $169K *
Lead the charge in establishing and overseeing the Cleanroom EM program while ensuring compliance with GMP standards. Engage collaboratively across departments to support production readiness and main...
1 week ago
Senior Scientist, Chemistry at Attaineo
$90K - $120K *
Contribute to innovative drug discovery by applying advanced synthetic methodologies and collaborating with a dynamic team on multi-step synthesis and optimization processes to advance medicinal chemi...
Reposted 2 weeks ago
Principal Environmental Engineer / Scientist
$100K - $130K *
Lead the charge in complex environmental remediation projects, guiding multidisciplinary teams and advising clients on regulatory and risk considerations to develop sustainable solutions for contamina...
1 week ago
Scientist, Bioanalytical Development
$90K - $120K *
Join us as you lead the development of bioanalytical methods for preclinical and clinical programs, providing expertise in large molecule analysis and project management to support drug development ca...
2 weeks ago
$122K - $147K *
Innovate scientific solutions while leading and mentoring a team of researchers. Drive experimental design, optimize platform performance, and collaborate cross-functionally to enhance research outcom...
1 week ago
$90K - $120K *
Lead the charge in technical leadership, client relationship management, and project delivery. Ensure projects are completed safely and on time while mentoring staff and driving business growth in env...
2 weeks ago
$80K - $110K *
Champion project delivery by leading teams, ensuring environmental compliance, and driving business growth through client engagement and technical excellence in a fast-paced consulting environment...
2 weeks ago
$88K - $133K *
Join a team that's dedicated to environmental protection and data accuracy, tackling complex challenges as a Project Chemist. Collaborate on QA project plans, ensuring high-quality data for a sustaina...
1 week ago
Senior Scientist, Biocatalysis
$117K - $184K *
Engineer cutting-edge biocatalytic solutions to advance drug development and therapeutic innovations by leveraging interdisciplinary collaboration and deep scientific expertise to solve complex bioche...
2 weeks ago
Principal Scientist - Formulation
$150K - $180K *
Lead formulation strategies for innovative long-acting oral drug delivery solutions in a fast-paced biotech environment. Oversee product development from feasibility to manufacture, guiding teams on o...
2 days ago
Associate Scientist, Protein Sciences
$80K - $120K *
Accelerate progress at the forefront of biopharmaceutical research, leading antibody development and protein production initiatives for novel oncology targets. Collaborate in a dynamic environment to...
1 week ago
Principal AI Workflow Engineer
$196K - $314K *
Empower the future of embedded systems by integrating AI technologies into firmware engineering. Lead initiatives on AI adoption, tool development, and scalable infrastructure while collaborating acro...
2 weeks ago
Senior Scientist - GMP Laboratory
$95K - $115K *
Join a team that's driving innovative laboratory solutions, performing complex testing, and mentoring junior scientists. Lead method development and execution while ensuring data accuracy and complian...
Reposted today
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.