Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$120K - $160K *

Shape your career by leading projects in power system planning. Collaborate with clients to navigate regulatory challenges and enhance energy strategies, while managing teams and driving innovative so...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$90K - $120K *

Pioneer hands-on radiochemical operations in a fast-paced lab dedicated to isotope production, supporting safety and compliance while developing expertise in nuclear processes and analytical chemistry...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $140K *

Pioneer the marketing strategy for a cutting-edge healthcare AI company, translating complex scientific narratives into compelling messages. Collaborate with leadership to drive product launches, cont...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $130K *

Drive impactful medical writing initiatives by leading document development for regulatory and clinical needs. Collaborate with cross-functional teams to deliver high-quality submissions while mentori...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$87K - $131K *

Unlock your potential as a Datacenter Engineer, driving the lifecycle and support of multi-vendor hardware in a dynamic lab environment. Collaborate, troubleshoot, and innovate to optimize performance...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$112K - $149K *

Contribute to strategic pricing proposals for government contracts, ensuring compliance and accuracy. Collaborate across teams to drive financial assessments, optimize proposals, and support continuou...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$154K - $242K *

Empower your career by leading operational strategies in oncology trials. Collaborate with cross-functional teams and oversee clinical programs to ensure high-quality, timely execution. Drive innovati...

US-AnywhereRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $120K *

Drive impactful cybersecurity assessments and risk evaluations for clients, enhancing security postures across diverse environments. Lead teams, mentor peers, and streamline methodologies while engagi...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $150K *

Lead the operational execution of complex cell-therapy clinical trials, ensuring compliance and efficiency from setup through final reporting while overseeing cross-functional teams and vendor relatio...

US-AnywhereRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$133K - $170K *

Join a team that's dedicated to enhancing compliance and transparency in healthcare. Lead initiatives in policy development and training while ensuring adherence to legal standards and fostering stron...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $173K *

Lead the charge in managing complex projects with multi-million dollar budgets. You'll ensure timely delivery and scope adherence while leveraging expertise in project governance, material handling, a...

US-AnywhereRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Business Services

$115K - $173K *

Grow your career with a key role overseeing complex warehouse automation projects, managing executive relationships, and driving performance across multi-disciplinary teams from beginning to successfu...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$120K - $160K *

Empower your career by architecting scalable systems for large-scale data ingestion and AI analytics. Lead technical innovations and mentor engineers in a dynamic startup environment, driving impactfu...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$186K - $233K *

Shape the future of oncology by driving HEOR strategies that deliver evidence supporting treatment decisions for gastrointestinal cancers, collaborating with cross-functional teams to optimize outcome...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$118K - $184K *

Engineer robust automation script frameworks to enhance network testing workflows. Collaborate with DevTestOps teams to integrate AI solutions, optimizing verification phases and ensuring reliable sof...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$123K - $176K *

Drive complex SAP projects by leading deliverables, facilitating workshops, and optimizing business processes to enhance system functionality and deliver impactful solutions within the SAP Center of E...

US-AnywhereRemote

5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$131K - $237K *

Elevate enterprise architecture by providing strategic guidance on Oracle ERP and modern technologies to meet federal HR modernization needs. Collaborate with teams to identify gaps and create actiona...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$180K - $200K *

Lead electrical design standards and oversee technical reviews for critical systems. Collaborate across teams to ensure compliance, mitigate risks, and enhance operational reliability in our hyperscal...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Technical Services

$280K - $320K *

Optimize capture strategies and lead high-value government contract pursuits while driving strategic growth initiatives. Collaborate with senior stakeholders and build customer relationships to enhanc...

US-AnywhereRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$175K - $195K *

Drive cross-functional product strategies and commercialization efforts in a fast-paced biotech setting, ensuring alignment on key objectives while translating complex scientific data into actionable...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$96K - $150K *

Contribute to impactful voter/donor management systems by leading complex features with deep technical expertise. Mentor peers and drive architectural improvements while enhancing product health for p...

US-AnywhereRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $100K *

Advance your career as a Senior CRA by overseeing clinical monitoring and site management, ensuring regulatory compliance, and leading small projects. Bring your expertise to a dynamic team dedicated...

US-AnywhereRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$105K - $125K *

Engage with healthcare clients to identify product opportunities and drive impactful initiatives. Collaborate across teams to develop strategies for effective screening, credentialing, and onboarding...

US-AnywhereRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$177K - $292K *

Lead the charge in validating product satisfaction through robust beta programs. Manage a team to design testing frameworks and ensure rigorous data-driven insights guide product launches at scale. Co...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$160K - $220K *

Lead the charge in driving data science initiatives, transforming complex datasets into strategic insights and scalable solutions that impact multiple business areas while fostering cross-functional c...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.