Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$85K - $100K *

Engage in impactful Natural Resources projects, leading field surveys and managing teams nationwide. Balance hands-on fieldwork with strategic project oversight to ensure compliance, quality, and stak...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$133K - $248K *

Lead the charge in driving product strategy and execution, managing a high-performing team while navigating market dynamics to achieve sustainable growth and competitive advantage in healthcare equipm...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$170K - $182K *

Unlock innovative advancements in manufacturing and materials for energy. Lead R&D projects, guiding teams and influencing technical strategies while addressing complex industry challenges with minima...

US-AnywhereRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

$99K - $132K *

Join a team that's dedicated to innovative project management for gene variant libraries. Collaborate across departments to ensure seamless communication and design for customers while maintaining pre...

US-AnywhereRemote

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$97K - $156K *

Elevate digital marketing effectiveness by leading personalization initiatives, managing a team to enhance customer engagement, and optimizing strategies that drive targeted, measurable results across...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Unlock your potential by driving financial planning and analysis for strategic initiatives. Partner with leaders to align financial strategies, enhance models, and deliver insights that enable busines...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$129K - $160K *

Oversee preclinical operations by managing non-GLP and GLP toxicology studies, ensuring scientific and corporate goals are achieved while complying with regulatory standards and fostering collaboratio...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$164K - $225K *

Elevate safety standards by driving proactive surveillance, ensuring rigorous data analysis, and leading interdisciplinary teams to identify and assess safety signals for investigational and marketed...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that leads clinical trials in dermatology and rheumatology. You'll manage projects from initiation to closure, ensuring timely deliverables and budget adherence while empowering cross-func...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$195K - $210K *

Drive innovation as a key technical leader, overseeing complex software projects, mentoring teams, and establishing AI-first development standards. Your expertise will enhance the delivery of scalable...

US-AnywhereRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$112K - $153K *

Develop and execute strategic sales initiatives, guiding a team of specialists to enhance market presence and drive revenue growth in the life sciences sector while fostering strong client relationshi...

US-AnywhereRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$175K - $222K *

Architect scalable AI-driven software development processes by overseeing generator-verifier frameworks, ensuring compliance with top-tier standards while bridging human oversight and autonomous agent...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$147K - $160K *

Optimize operational excellence by leading cross-functional teams in complex tech ops initiatives. Drive project success through strategic program management, mentorship, and continuous improvement wh...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$88K - $105K *

Empower clinical trial success by strategically reviewing protocols, advising Project Managers, and ensuring database consistency while collaborating cross-departmentally to meet client and internal r...

US-AnywhereRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Empower software innovation by leading a team in coding and architecture, guiding performance, conducting technical discussions, and driving process improvements for a high-performing product delivery...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Shape the future of reimbursement project assessments by leading technical reviews, guiding analysts, and establishing impactful frameworks, standards, and processes. Collaborate cross-functionally to...

US-AnywhereRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$221K - $286K *

Lead the charge in establishing a robust microbiology and sterility assurance strategy. Oversee global governance, technical standards, and compliance while driving operational excellence and collabor...

US-AnywhereRemote

4 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Oversee a diverse portfolio of environmental modeling and operational projects, driving innovation and effective project management while collaborating with multidisciplinary teams to meet NOAA's obje...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$99K - $130K *

Join a team that's committed to driving innovation in brand consulting. Lead client relationships, mentor junior staff, and utilize your brand tracking expertise to deliver impactful insights and fost...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$145K - $175K *

Unlock potential by architecting and scaling AI solutions that enhance scientific research. Collaborate across teams to prototype LLM-enabled capabilities, identify high-impact opportunities, and impr...

US-AnywhereRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$219K - $349K *

Architect a dynamic government growth strategy that drives significant revenue and market expansion while leading a high-performing sales team across federal and state agencies. Engage directly with s...

US-AnywhereRemote

1 week ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$135K - $155K *

Unlock potential by leading advanced quantitative research methodologies, improving analytical standards, and guiding teams in challenging statistical challenges for impactful research solutions acros...

US-AnywhereRemote

5 days ago

  •   8 - 10 years exp.  •   Business Services

$125K - $150K *

Champion the strategic execution of CMC activities for radiopharmaceuticals, ensuring readiness for commercial launch and ongoing viability through effective collaboration across global teams and exte...

US-AnywhereRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Shape the future of radiopharmaceutical development by leading cross-functional CMC initiatives, coordinating key activities, and ensuring seamless collaboration to achieve successful commercial launc...

US-AnywhereRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$118K - $177K *

Pioneer strategic growth initiatives, build client relationships, and drive market expansion in the qPCR industry. Lead cross-functional teams to identify opportunities, analyze market trends, and exe...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.