Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$275K - $375K *

Join a team that's shaping the future of AI infrastructure, leading the development of our AI Gateway and driving innovation in high-performance, distributed systems while mentoring top engineering ta...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $120K *

Optimize project coordination and eTMF activities, providing essential support to teams and clients while ensuring compliance and timely delivery of clinical project milestones and documentation...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$99K - $119K *

Lead the charge in optimizing TMF operations by ensuring clinical trial documentation is flawless and inspection-ready. Collaborate with teams to enhance quality, identify risks, and drive compliance...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $208K *

Engage with the global AI and automation markets, identifying trends and insights in integration and API management, while collaborating with analysts to provide expert research and analysis for techn...

US-AnywhereRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Lead the charge in developing innovative drilling solutions to enable large-diameter borehole construction. Collaborate cross-functionally to ensure safe and efficient execution, while building a robu...

US-AnywhereRemote

1 week ago

  •   11 - 15 years exp.  •   Energy & Utilities

$100K - $125K *

Lead the transformation of supply chain processes by analyzing needs, optimizing ERP systems, and fostering cross-functional partnerships to enhance operational efficiency and meet strategic goals in...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$140K - $170K *

Discover innovative solutions as a Senior Data Scientist, leading AI and ML initiatives in healthcare. Collaborate with a talented team to analyze complex data sets, develop models, and influence tech...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in statistical activities for global clinical trials, collaborating with cross-functional teams and ensuring adherence to standards while providing expert analysis and guidance through...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $190K *

Optimize global health initiatives by providing strategic technical leadership across multiple programs. Drive innovation, oversee project quality, and collaborate with stakeholders to enhance public...

US-AnywhereRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$168K - $304K *

Innovate in synthetic data generation for multimodal applications, enhancing LLMs through collaboration and open-source contributions while driving software excellence and research publication...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$178K - $222K *

Innovate within a dynamic team by establishing bioinformatics capabilities, architecting scalable infrastructure, and enhancing genomic algorithms to drive excellence in women's and organ health produ...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$171K - $231K *

Partner with us to lead strategic operational planning in global clinical programs. This role requires building and managing diverse global teams and driving collaboration across functions to ensure e...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$140K - $170K *

Contribute to innovative pavement management projects, overseeing evaluation, design, and preservation efforts while collaborating with clients across various levels. Embrace opportunities for career...

US-AnywhereRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Transportation

$151K - $226K *

Elevate your career by conducting impactful analyses on Real-World Data (RWD) for vital RWE studies. Collaborate with experts to produce rigorous, high-quality results that inform healthcare decisions...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $163K *

Drive innovation in bioinformatics to enhance diagnostic assays for women's and organ health. Collaborate cross-functionally to build algorithms that accurately detect genomic variants, ensuring relia...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$200K - $220K *

Transform healthcare marketing by leading the HCP launch strategy, leveraging insights to boost engagement and adoption in an entrepreneurial, fully remote environment. Cultivate impactful campaigns a...

US-AnywhereRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Empower growth in clinical research by leading rare disease strategy and client engagements, collaborating with senior leadership to drive measurable outcomes and innovation within a dynamic pharmaceu...

US-AnywhereRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$155K - $233K *

Drive the design and implementation of cutting-edge bioinformatics algorithms, optimizing genomic signal analysis software while collaborating with teams to enhance results for researchers and clinici...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$79K - $139K *

Optimize bioanalytical methods development and validation while supervising staff, driving innovation, and enhancing laboratory processes to meet client needs within established timelines and regulato...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$152K - $223K *

Join a forward-thinking team shaping the future of enterprise integration through innovative API strategies, driving automation and fostering collaboration across technologies to enhance business outc...

US-AnywhereRemote

Reposted today

  •   8 - 10 years exp.  •   Enterprise Technology

$205K - $239K *

Elevate your career by leading MSAT initiatives driving small molecule drug manufacturing. Oversee the entire facility lifecycle ensuring robust processes, compliance, and operational readiness in col...

US-AnywhereRemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$79K - $139K *

Join a team that's shaping the future of bioanalytical methods through innovative development, validation, and analysis, while driving process improvements and mentoring scientific staff for excellenc...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$132K - $172K *

Grow your expertise in CMC Regulatory Affairs, leading strategic initiatives for small molecule drug products from development through commercialization. Collaborate cross-functionally to align regula...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Drive the strategic commercial performance across North America in the ImmunoDiagnostics sector, leading direct and distributor sales, shaping clinical go-to-market strategies, and ensuring sustained...

US-AnywhereRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$140K - $150K *

Address critical project management needs for global clinical trials, ensuring successful execution of Phase I studies. Lead diverse teams, maintain timelines, and foster client relationships while ad...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.