Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
Principal Scientist, CMC Analytical
$150K - $190K *
Unlock potential by leading analytical strategies for drug development, ensuring robust quality control throughout product lifecycle. Collaborate with partners to deliver exceptional insights that dri...
1 week ago
Senior Scientific Project Manager
$100K - $130K *
Tackle complex scientific projects by overseeing biopharmaceutical assay development and validation. Collaborate with teams to ensure timely delivery of quality data, manage vendor relationships, and...
1 week ago
Principal Scientist Algorithm Lead
$151K - $261K *
Elevate NGS diagnostic innovation by leading algorithm development to enhance clinical outcomes. Drive analytical validation, regulatory readiness, and algorithm performance in oncology, focusing on s...
2 weeks ago
Senior Principal Scientist, Drug Substance
$175K - $230K *
Elevate drug substance development by leading process innovation and CDMO partnerships. Drive projects from early development through commercialization, ensuring regulatory compliance and strategic al...
4 weeks ago
Senior Principal, AI Product Owner - Agentic AI
$175K - $230K *
Lead the charge in shaping AI products for a resilient global supply chain. Drive strategies, governance, and scalable AI delivery while partnering across teams to enhance data readiness and operation...
2 weeks ago
Senior Principal, AI Product Owner - LLMs
$175K - $230K *
Lead the strategy and implementation of AI-driven products leveraging large language models to enhance supply chain efficiency. Collaborate with cross-functional teams to ensure data readiness and dri...
2 weeks ago
Director, Scientific Solutions
$130K - $180K *
Join us as a key leader in driving the commercial strategy for scientific solutions while developing a high-performance team that engages top-tier clients in the life sciences sector. Own flagship acc...
2 weeks ago
$120K - $150K *
Lead a multidisciplinary team in shaping impactful research agendas, driving innovation in scientific applications while developing talent and overseeing projects from hypothesis to deployment...
Today
Principal Scientist, Translational Oncology - Single Cell and Spatial Genomics, Solid Tumors
$171K - $214K *
Join a pioneering oncology research team to lead translational projects, integrating cutting-edge single-cell and spatial biology technologies to enhance drug discovery and clinical applications acros...
3 weeks ago
Senior Principal, AI Product Owner - Machine Learning
$175K - $230K *
Drive your career with innovative AI and machine learning products that enhance global supply chain efficiency. Own strategy, elevate data standards, lead governance, and foster collaboration in a sen...
2 weeks ago
$120K - $150K *
Transform the future of drug development by leading innovative simulation projects, acting as a scientific liaison between clients and teams, and driving advances in pharmacometrics with your expertis...
2 weeks ago
Senior Project Manager, Promotional Medical Education
$90K - $100K *
Join a dynamic team to lead and deliver complex client campaigns, managing timelines, budgets, and stakeholder engagement to drive high-quality results across multiple accounts. Your expertise in proj...
4 days ago
Senior Director, AI Risk and Compliance
$167K - $278K *
Elevate your career by shaping AI governance and compliance frameworks that ensure responsible AI deployment while driving measurable business impact in clinical research. Lead a team committed to tra...
1 week ago
Senior Clinical Scientist, ECD
$142K - $178K *
Lead the charge in clinical development for early cancer detection by driving study execution, data review, and strategic insight. Collaborate with cross-functional teams to enhance clinical strategy...
2 weeks ago
$88K - $154K *
Innovate within complex environmental projects as a Principal Scientist, leading interdisciplinary teams to develop effective remediation and restoration solutions while ensuring compliance with regul...
1 week ago
$113K - $151K *
Lead our IT operations to enhance global research and healthcare initiatives. Drive digital transformation, manage resources, and collaborate with stakeholders to ensure excellence in service delivery...
Reposted 1 week ago
Principal Scientist – Data Insights & Hypothesis Design
$150K - $225K *
Shape the future of precision medicine by leveraging multimodal data insights to transform clinical care, enhancing drug discovery and patient treatment through advanced scientific methodologies and c...
1 week ago
Director, PF Project Delivery - Project Farma
$150K - $170K *
Accelerate progress at leading innovative projects while driving business growth and team success through strategic leadership, client engagement, and operational excellence in the biomanufacturing se...
Reposted 1 week ago
Senior Manager, Marketing Program Management
$135K - $190K *
Join a team that's shaping the future of marketing through innovative program management, leading strategic campaigns, and leveraging AI tools for enhanced productivity and effectiveness in a dynamic...
1 week ago
$152K - $190K *
Join a team that's shaping the future of healthcare through innovative software solutions. As a technical leader, you'll drive the design and development of next-gen clinical data platforms while ment...
Reposted 3 weeks ago
Senior Research Scientist, Evidence Synthesis
$90K - $120K *
Lead innovative projects in evidence synthesis as a Senior Research Scientist, collaborating across multiple teams to develop client-ready deliverables and oversee systematic reviews while mentoring j...
2 weeks ago
Sr. Field Application Scientist - Chemistry/Formulations
$100K - $125K *
Engage your passion for chemistry as you drive sales success by collaborating with teams, conducting demos, and providing insights to elevate product offerings and enhance customer engagement, all whi...
1 week ago
$66K - $99K *
Shape the future of environmental projects by leading assessments, remediation, and team management. Drive successful project delivery while mentoring talent and maintaining client relationships throu...
2 weeks ago
$66K - $99K *
Champion environmental project success through management of assessments, remediation, and stakeholder communications while mentoring junior staff and ensuring compliance with regulations and timeline...
2 weeks ago
$116K - $146K *
Optimize detection and diagnostics for solar assets by building scalable ML models. Collaborate across teams to translate insights into actionable improvements, enhancing performance and customer expe...
6 days ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.