Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$151K - $175K *

Elevate NGS diagnostic innovation by leading algorithm development to enhance clinical outcomes. Drive analytical validation, regulatory readiness, and algorithm performance in oncology, focusing on s...

US-AnywhereRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a team that's dedicated to conducting comprehensive environmental assessments, identifying risks, and ensuring regulatory compliance while leading innovative projects in environmental science and...

US-AnywhereRemote

5 days ago

  •   8 - 10 years exp.  •   Technical Services

$152K - $205K *

Lead the charge in developing innovative nonclinical safety strategies for drug development, serving as a Subject Matter Expert and project team representative to ensure compliance with regulatory sta...

US-AnywhereRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$275K - $350K *

Join a team that builds integrated nonclinical safety strategies for oligonucleotide therapeutics, guiding studies from candidate selection through clinical development while ensuring scientific rigor...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Engineer advanced protein design models and collaborate with experts to innovate in AI Drug Discovery, driving the development of candidate antibody therapeutics through deep learning and systems biol...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$200K - $300K *

Shape the future of embodied intelligence by leading groundbreaking research in Vision AI and multimodal foundation models. Collaborate with a dynamic team to create innovative solutions that advance...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$165K - $290K *

Unlock potential by leading real-world evidence strategies for Cardiometabolic Health. Drive innovative data solutions, oversee impactful research initiatives, and collaborate cross-functionally to en...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Pioneer transformative AI applications in biomedical discovery, collaborating with scientists and engineers to bridge virtual and real-world data for innovative drug discovery solutions...

US-AnywhereRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$140K - $220K *

Lead critical analytics projects, guiding teams in statistical modeling and data quality improvement to deliver actionable insights in the credit risk domain. Collaborate effectively with cross-functi...

US-AnywhereRemote

5 days ago

  •   5 - 7 years exp.  •   Business Services

$100K - $155K *

Join a team that's dedicated to optimizing bioprocess technologies. Leverage your expertise in cell culture and bioprocessing to deliver technical support and solutions for customers, enhancing their...

US-AnywhereRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Empower engineering excellence by solving complex technical challenges, mentoring teams, and driving innovative software solutions in a collaborative, cloud-native environment focused on data and AI i...

US-AnywhereRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$500K+*

Shape the future of our ad ecosystem by developing machine learning models and optimization algorithms that enhance ad performance while balancing revenue and user experience. Collaborate closely with...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$80K - $95K *

Join a dedicated team to oversee biospecimen lifecycle management, ensuring timely and efficient data utilization from clinical studies while acting as the primary liaison between sponsors and stakeho...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $140K *

Transform customer experiences through expert guidance and support in application development, training, and troubleshooting. Collaborate cross-functionally to ensure successful technology adoption an...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$168K - $210K *

Engage in shaping AI-enabled software architecture, translating business needs into secure, scalable solutions while mentoring teams and collaborating across functions on modern engineering and respon...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$141K - $196K *

Champion the future of transformative decision systems by guiding teams on optimizing offer strategies, conversion modeling, and systems design to enhance borrower experiences and improve marketplace...

US-AnywhereRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Transform AI research into actionable insights. Collaborate with teams to prioritize projects, set milestones, and evaluate ROI, driving accountable progress while fostering a culture of scientific ex...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$95K - $115K *

Pioneer the future of clinical project management by leading teams, guiding projects, and enforcing quality standards. Collaborate effectively with various departments to meet client specifications an...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$105K - $135K *

Shape the future of media analytics as you drive innovative reporting and optimization strategies for omnichannel clients, translating data into actionable insights that enhance campaign performance a...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$145K - $212K *

Drive the development of AI-driven solutions for life-sciences research, collaborating across teams to transition innovative features from concept to launch, while ensuring alignment with researchers...

US-AnywhereRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$131K - $165K *

Innovate clinical solutions by leading global study design and scientific strategy. Drive regulatory submissions and evidence generation, collaborating across teams to enhance medical device technolog...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$145K - $240K *

Join a team that's redefining health outcomes through cutting-edge research. Leverage your expertise in human physiology and regenerative medicine to support innovative programs in transplantation and...

US-AnywhereRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$207K - $258K *

Unlock potential by providing expert leadership in process chemistry for small molecule development, collaborating cross-functionally to innovate manufacturing strategies and ensure seamless progressi...

US-AnywhereRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead strategic nutrition initiatives for clinical trials, driving innovation and operational excellence. Oversee program design, quality execution, and vendor partnerships while managing cross-functio...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Food & Beverages

$194K - $262K *

Shape the future of drug development as you lead nonclinical safety strategies, influence cross-functional teams, and drive innovative assessment methodologies to support new therapeutics across diver...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.