Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
Principal Scientist Algorithm Lead
$151K - $175K *
Elevate NGS diagnostic innovation by leading algorithm development to enhance clinical outcomes. Drive analytical validation, regulatory readiness, and algorithm performance in oncology, focusing on s...
Reposted 1 week ago
$100K - $120K *
Join a team that's dedicated to conducting comprehensive environmental assessments, identifying risks, and ensuring regulatory compliance while leading innovative projects in environmental science and...
5 days ago
Principal Scientist, Project Toxicologist
$152K - $205K *
Lead the charge in developing innovative nonclinical safety strategies for drug development, serving as a Subject Matter Expert and project team representative to ensure compliance with regulatory sta...
6 days ago
Senior Director/Vice President, Oligo Toxicology
$275K - $350K *
Join a team that builds integrated nonclinical safety strategies for oligonucleotide therapeutics, guiding studies from candidate selection through clinical development while ensuring scientific rigor...
3 weeks ago
Senior/Staff AI Scientist, Target Discovery
$150K - $180K *
Engineer advanced protein design models and collaborate with experts to innovate in AI Drug Discovery, driving the development of candidate antibody therapeutics through deep learning and systems biol...
3 weeks ago
Principal Research Scientist - Vision AI, Simulation & Physical AI
$200K - $300K *
Shape the future of embodied intelligence by leading groundbreaking research in Vision AI and multimodal foundation models. Collaborate with a dynamic team to create innovative solutions that advance...
Reposted 1 week ago
$165K - $290K *
Unlock potential by leading real-world evidence strategies for Cardiometabolic Health. Drive innovative data solutions, oversee impactful research initiatives, and collaborate cross-functionally to en...
2 weeks ago
$130K - $160K *
Pioneer transformative AI applications in biomedical discovery, collaborating with scientists and engineers to bridge virtual and real-world data for innovative drug discovery solutions...
3 days ago
Sr. Scientist, Analytic Science
$140K - $220K *
Lead critical analytics projects, guiding teams in statistical modeling and data quality improvement to deliver actionable insights in the credit risk domain. Collaborate effectively with cross-functi...
5 days ago
$100K - $155K *
Join a team that's dedicated to optimizing bioprocess technologies. Leverage your expertise in cell culture and bioprocessing to deliver technical support and solutions for customers, enhancing their...
Reposted today
$130K - $160K *
Empower engineering excellence by solving complex technical challenges, mentoring teams, and driving innovative software solutions in a collaborative, cloud-native environment focused on data and AI i...
5 days ago
Research Scientist 6 - Ad Marketplace
$500K+*
Shape the future of our ad ecosystem by developing machine learning models and optimization algorithms that enhance ad performance while balancing revenue and user experience. Collaborate closely with...
3 weeks ago
$80K - $95K *
Join a dedicated team to oversee biospecimen lifecycle management, ensuring timely and efficient data utilization from clinical studies while acting as the primary liaison between sponsors and stakeho...
1 week ago
Senior Field Application Scientist
$120K - $140K *
Transform customer experiences through expert guidance and support in application development, training, and troubleshooting. Collaborate cross-functionally to ensure successful technology adoption an...
3 weeks ago
$168K - $210K *
Engage in shaping AI-enabled software architecture, translating business needs into secure, scalable solutions while mentoring teams and collaborating across functions on modern engineering and respon...
1 week ago
$141K - $196K *
Champion the future of transformative decision systems by guiding teams on optimizing offer strategies, conversion modeling, and systems design to enhance borrower experiences and improve marketplace...
Reposted 2 weeks ago
$110K - $130K *
Transform AI research into actionable insights. Collaborate with teams to prioritize projects, set milestones, and evaluate ROI, driving accountable progress while fostering a culture of scientific ex...
1 week ago
$95K - $115K *
Pioneer the future of clinical project management by leading teams, guiding projects, and enforcing quality standards. Collaborate effectively with various departments to meet client specifications an...
2 weeks ago
$105K - $135K *
Shape the future of media analytics as you drive innovative reporting and optimization strategies for omnichannel clients, translating data into actionable insights that enhance campaign performance a...
2 weeks ago
Director of Product, Applied Research Intelligence
$145K - $212K *
Drive the development of AI-driven solutions for life-sciences research, collaborating across teams to transition innovative features from concept to launch, while ensuring alignment with researchers...
Reposted 2 days ago
Principal Scientist | REMOTE (Valencia (CA), United States)
$131K - $165K *
Innovate clinical solutions by leading global study design and scientific strategy. Drive regulatory submissions and evidence generation, collaborating across teams to enhance medical device technolog...
2 weeks ago
Senior Scientist / Engineer (Human Physiology Systems / Bioengineering)
$145K - $240K *
Join a team that's redefining health outcomes through cutting-edge research. Leverage your expertise in human physiology and regenerative medicine to support innovative programs in transplantation and...
4 days ago
$207K - $258K *
Unlock potential by providing expert leadership in process chemistry for small molecule development, collaborating cross-functionally to innovate manufacturing strategies and ensure seamless progressi...
5 days ago
Associate Director, Food Sciences
$110K - $130K *
Lead strategic nutrition initiatives for clinical trials, driving innovation and operational excellence. Oversee program design, quality execution, and vendor partnerships while managing cross-functio...
Reposted 2 weeks ago
Scientific Associate Director - Project Toxicologist
$194K - $262K *
Shape the future of drug development as you lead nonclinical safety strategies, influence cross-functional teams, and drive innovative assessment methodologies to support new therapeutics across diver...
3 weeks ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.